Results 121 to 130 of about 23,717 (182)
TLR9 signaling activation at different stages in colorectal cancer and NF-kappaB expression. [PDF]
Onco Targets Ther, 2018 Gao C +5 more
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Dihydromyricetin Attenuates Inflammation through TLR4/NF-kappaB Pathway.
Open Med (Wars), 2019 Jing N, Li X.
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NF-kappaB and reperfusion injury
Drug News & Perspectives, 2004This review discusses the current understanding of mechanisms that mediate activation of the transcription factor nuclear factor-kappaB (NF-kappaB) and how such activation could in turn mediate reperfusion injury. NF-kappaB regulates the expression of several genes involved in inflammation, the immune response, apoptosis, cell survival and ...
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NF-kappaB-inducing kinase in cancer
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 2019Dysregulation of the alternative NF-κB signaling has severe developmental consequences that can ultimately lead to oncogenesis. Pivotal for the activation of the alternative NF-κB pathway is the stabilization of the NF-κB-inducing kinase (NIK). The aim of this review is to focus on the emerging role of NIK in cancer. The documented subversion of NIK in
Gunter Maubach +3 more
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British Journal of Dermatology, 2003
Nuclear factor-kappaB (NF-kappaB) is a transcription factor involved in a number of signalling pathways in many cell types. NF-kappaB in mice has been implicated as an important regulator of keratinocyte proliferation and differentiation.To evaluate the role of NF-kappaB in keratinocyte growth in human beings, we examined its expression in ...
J, Takao +6 more
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Nuclear factor-kappaB (NF-kappaB) is a transcription factor involved in a number of signalling pathways in many cell types. NF-kappaB in mice has been implicated as an important regulator of keratinocyte proliferation and differentiation.To evaluate the role of NF-kappaB in keratinocyte growth in human beings, we examined its expression in ...
J, Takao +6 more
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NF-kappaB in the nervous system.
Cold Spring Harbor perspectives in biology, 2009The transcription factor NF-kappaB has diverse functions in the nervous system, depending on the cellular context. NF-kappaB is constitutively activated in glutamatergic neurons. Knockout of p65 or inhibition of neuronal NF-kappaB by super-repressor IkappaB resulted in the loss of neuroprotection and defects in learning and memory.
Kaltschmidt, Barbara +1 more
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NF-kappaB in the immune response of Drosophila.
Cold Spring Harbor perspectives in biology, 2009The nuclear factor kappaB (NF-kappaB) pathways play a major role in Drosophila host defense. Two recognition and signaling cascades control this immune response. The Toll pathway is activated by Gram-positive bacteria and by fungi, whereas the immune deficiency (Imd) pathway responds to Gram-negative bacterial infection.
Hetru, Charles, Hoffmann, Jules
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NF-kappaB in renal inflammation.
Journal of the American Society of Nephrology : JASN, 2010The NF-kappaB family of transcription factors regulates the induction and resolution of inflammation. Two main pathways, classical and alternative, control the nuclear translocation of NF-kappaB. Classical NF-kappaB activation is usually a rapid and transient response to a wide range of stimuli whose main effector is RelA/p50. The alternative NF-kappaB
Ana Belen, Sanz +7 more
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Genes & development, 2004
The transcription factor NF-kappaB has been the focus of intense investigation for nearly two decades. Over this period, considerable progress has been made in determining the function and regulation of NF-kappaB, although there are nuances in this important signaling pathway that still remain to be understood.
Matthew S, Hayden, Sankar, Ghosh
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The transcription factor NF-kappaB has been the focus of intense investigation for nearly two decades. Over this period, considerable progress has been made in determining the function and regulation of NF-kappaB, although there are nuances in this important signaling pathway that still remain to be understood.
Matthew S, Hayden, Sankar, Ghosh
openaire +1 more source