Results 161 to 170 of about 43,575 (292)

Correlation between in vivo 18F‐flortaucipir PET and whole‐brain postmortem histological tau signals in Alzheimer's disease

Alzheimer's &Dementia, Volume 22, Issue 5, May 2026.
Abstract INTRODUCTION Clinicopathological studies offer crucial interpretations of 18F‐flortaucipir (FTP) tau positron emission tomography (PET) signal but are limited by methods. We leveraged whole‐brain, quantitative immunohistochemical (IHC) Alzheimer's Disease (AD) tau density maps to comprehensively evaluate the FTP tracer.
Yishu Chao, Yuheng Chen, Trevor A. Chadwick, Theresa M. Harrison, Leonardo Iaccarino, Helmut Heinsen, Daniela Ushizima, Duygu Tosun, William J. Jagust, Lea T. Grinberg   +9 more
wiley   +1 more source

How does type 2 diabetes modify the risk of Alzheimer's disease?

Alzheimer's &Dementia, Volume 22, Issue 5, May 2026.
Abstract Type 2 diabetes (T2D) and Alzheimer's disease (AD) are both increasing exponentially worldwide. T2D has also been identified as one of 14 modifiable risk factors for dementia, but the mechanism is unknown. T2D could promote dementia via vascular or AD neuropathological changes, and mechanistic hypotheses include central insulin resistance and ...
G. T. Sutherland, A. Chen, H‐T. Nguyen‐Hao, H. Mundell, E. Aladyeva, M. J. Hofer, O. Harari, S. M. Twigg   +7 more
wiley   +1 more source

The role of non-fungible tokens in education: A comprehensive review and future directions

Social Sciences and Humanities Open
Non-fungible tokens (NFTs) possess transformative potential in the educational sector, facilitating digital content creation, ownership, and exchange while fostering advancements in personalized learning, certification, and resource sharing.
Agariadne Dwinggo Samala, Soha Rawas, Zamzami Zainuddin, Natalie-Jane Howard, Sasha Shilina   +4 more
doaj   +1 more source

NFT Marketplace

International Journal of Scientific Research in Engineering and Management
Abstract— The rapid growth of blockchain technology has transformed the creation and exchange of digital assets through Non-Fungible Tokens (NFTs). Despite this progress, existing NFT marketplaces continue to face significant challenges, including high transaction costs, centralized metadata storage, lack of transparency in royalty distribution ...
SOUVIK DAS, DR. VAISHALI SHENDE, JITANSHU TIWARI, SUYASH SINGH, VIPUL SHARMA   +4 more
openaire   +1 more source

Uncovering distinct spatiotemporal trajectories of T‐N mismatch subtypes with likely co‐pathology in Alzheimer's disease using event‐based modeling

Alzheimer's &Dementia, Volume 22, Issue 5, May 2026.
Abstract INTRODUCTION In Alzheimer's disease (AD), tau–neurodegeneration (T–N) mismatch has been proposed to reflect non‐AD processes such as transactive response DNA binding protein 43 kDa and vascular disease. We aimed to characterize the spatiotemporal trajectories of T–N mismatch that may reflect non‐AD progression.
Xueying Lyu, Christopher A. Brown, Michael Tran Duong, Emma P. Fischer, Emily McGrew, David J. Irwin, Bradford C. Dickerson, Ilya M. Nasrallah, Russell Takeshi Shinohara, Alexandra L. Young, Paul A. Yushkevich, Sandhitsu R. Das, David A. Wolk, for the Alzheimer's Disease Neuroimaging Initiative   +13 more
wiley   +1 more source

PIB is a non-specific imaging marker of amyloid-beta (Aβ) peptide-related cerebral amyloidosis [PDF]

, 2017
The in vivo imaging probe [11C]-PIB (Pittsburgh Compound B, N-methyl[11C]2-(4′-methylaminophenyl-6-hydroxybenzathiazole) is under evaluation as a key imaging tool in Alzheimer's disease (AD) and to date has been assumed to bind with high affinity and ...
Beach, T.G., Joyce, J.N., Lamb, J.R., Leppert, D., Libri, V., Lockhart, A., Osredkar, T., Sue, L.I., Ye, L.   +8 more
core  

Age‐related behavioral and molecular landmarks in new mouse models for studying Alzheimer's disease in Down syndrome

Alzheimer's &Dementia, Volume 22, Issue 5, May 2026.
Abstract INTRODUCTION Down syndrome (DS) is the leading genetic cause of intellectual disability and Alzheimer's disease (AD), with over 90% of individuals developing AD‐related dementia (DSAD). The triplication of the APP gene on chromosome 21 drives early amyloid‐β (Aβ) accumulation, but other Hsa21 genes also contribute to pathology.
Monika Rataj Baniowska, Paige Mumford, Francesca Prestia, Pauline Stephan, Millie Beament, Marie‐Christine Birling, Chiara Lanzillotta, Letizia Ciafardini, Eugenio Barone, Gloria Lau, Claire Chevalier, Chadia Nahy, Nadia Messaddeq, Thais Lestra, Yixing Wu, Valérie Nalesso, Fabio Di Domenico, Frances Wiseman, Yann Herault   +18 more
wiley   +1 more source

Advanced Non‐Enzymatic Electrochemical Sensor Materials for Alzheimer's Disease Biomarkers

Analysis &Sensing, Volume 6, Issue 3, May 2026.
This review summarizes advances in materials‐driven, non‐enzymatic electrochemical biosensors for early Alzheimer's diagnosis via biofluid analysis. Amyloid‐β and hyperphosphorylated Tau are highlighted alongside sensor performance metrics, including sensitivity and selectivity.
Wei‐Ting Ting, Md Younus Ali, Claire Gage, Margaret Fahnestock, M. Firoz Mian, Matiar M. R. Howlader   +5 more
wiley   +1 more source

Neuroprotective Properties of Litchi chinensis and Its Phytochemicals in Preclinical Models of Alzheimer's Disease

Brain and Behavior, Volume 16, Issue 5, May 2026.
ABSTRACT Purpose Alzheimer's disease (AD) is a progressive neurodegenerative disorder involving amyloid‐β deposition, tau hyperphosphorylation, oxidative stress, and neuroinflammation. This review systematically evaluates the neuroprotective effects of Litchi chinensis and its phytochemicals against AD, focusing on modulation of Aβ accumulation, tau ...
Emon Mia, Md. Arif Hossain, Asmaul Husna Bristy, Rakib Hossan, Uzma Asif, Asif Khan Sherwani, Mohammad Y. Alshahrani, Samy Selim, Imam Hossen Rakib, Noshin Tasnim Yana, Khadija Akter, Md. Sakib Al Hasan   +11 more
wiley   +1 more source

Consumer Responses to Physical, Digital and Integrative Sustainability Strategies in the Apparel Industry: A Systematic Review

Business Strategy and the Environment, Volume 35, Issue 4, Page 4659-4687, May 2026.
ABSTRACT The apparel industry is one of the world's most profitable sectors but also among the most environmentally damaging. Growing sustainability pressures have led companies to adopt diverse strategies to reduce their impact, yet no single study has systematically analysed these approaches or their consumer implications.
Maria Leonor Ferreira, João J. Ferreira   +1 more
wiley   +1 more source