Results 171 to 180 of about 43,575 (292)
The digital economy has grown rapidly with the emergence of blockchain technology, which serves as the foundation for digital assets such as Non-Fungible Tokens (NFTs).
Syahrehan Ibnu Usman
doaj +1 more source
Multi‐target‐directed ligands (MTDLs) offer a promising strategy for Alzheimer's disease by simultaneously modulating amyloid‐β, tau pathology, neuroinflammation, and oxidative stress. This review highlights representative MTDL candidates and their therapeutic potential in addressing the multifactorial nature of AD.
Jaewoon Jung +5 more
wiley +1 more source
This study reveals a shift in woody plant community assembly from competitive exclusion in early succession to habitat filtering in later stages within karst areas. Environmental distance (80.54%) contributed significantly more than geographical distance (9.95%), providing strong quantitative evidence that niche processes, particularly habitat ...
Hongfen Hu +5 more
wiley +1 more source
Blockchain for the Arts and Humanities
ABSTRACT As born‐digital cultural materials proliferate, the arts and humanities require infrastructures that guarantee provenance, authenticity, and equitable access. This paper delivers a comprehensive, critical survey of blockchain's potential and limits across the sector.
James O'Sullivan
wiley +1 more source
ABSTRACT Gallic acid (GA), a plant‐derived phenolic compound, is evolving from a general antioxidant into a specific molecular modulator and a functional building block for advanced biomedical materials. This review synthesizes recent insights underpinned by GA's “redox duality”—its capacity to act as either a radical scavenger or a pro‐oxidant.
Woo Hyun Park
wiley +1 more source
Volatility spillovers across NFTs news attention and financial markets
Yizhi Wang
semanticscholar +1 more source
We investigated neuropathological manifestations of hypothermia in 168 cases. Patients aged 65 years or more constituted 80% of the total cohort. Alzheimer's disease was the most common comorbidity, affecting 40% of all patients. Abstract There is a paucity of autopsy‐based studies providing detailed neuropathological characteristics of fatal ...
Shojiro Ichimata +2 more
wiley +1 more source
The efficacy of the novel anti‐tau active immunotherapy, p5555kb, was tested using two mouse models of tau pathology. p5555kb inoculation increased the survival rate and reduced tau pathology in tau‐overexpressing P301L mice and decreased tau seeding in the brains of C57BL/6 mice injected with human‐purified Alzheimer's disease tau.
Christopher M. Brown +7 more
wiley +1 more source
14‐3‐3 protein homeostasis is disrupted in Lewy body pathology, showing a diminution of six isotypes and overexpression of stratifin. The latter was associated with stratifin colocalization with tau pathology and reactive astrocytes. Platelets, as a peripheral biomarker source, mirrored inversely cortical 14‐3‐3 gene expression patterns in dementia ...
Laura Marsal‐García +13 more
wiley +1 more source
ABSTRACT Background Limited existing research on mental health and health‐related quality of life (HRQoL) in people with hemophilia (PwH) suggests these patients still may have poor mental health despite treatment advances significantly improving somatic outcomes.
Francesca Schmitt +16 more
wiley +1 more source

