Results 31 to 40 of about 1,649 (145)

Morphological and molecular characterization of variation in common bean (Phaseolus vulgaris L.) germplasm from Azad Jammu and Kashmir, Pakistan.

open access: yesPLoS ONE, 2022
Phaseolus vulgaris, an essential food and source of protein, is cultivated across the world. This study was carried out to investigate the diversity and population structure of 34 P. vulgaris landrace accessions collected from the Azad Jammu and Kashmir (
Sidra Nasar   +3 more
doaj   +2 more sources

Frequency of ZFHX3‐Mediated Spinocerebellar Ataxia 4 in a US Undiagnosed Ataxia Cohort

open access: yesMovement Disorders, EarlyView.
Abstract Background Spinocerebellar ataxia 4 (SCA4) is a late‐onset dominant ataxia with neuropathy caused by exonic GGC repeat expansion in the ZFHX3 gene thought to originate from a Swedish founder event. The GC‐rich expansion is highly thermodynamically stable, posing challenges for standard clinical genetic testing methods.
Annie Chen   +320 more
wiley   +1 more source

Impact of incretin analogues on lipid and lipoprotein metabolism in obesity and diabetes

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Incretin‐based therapies have gained momentum as a key strategy for reducing cardiovascular risk in individuals with obesity and/or type 2 diabetes (T2D). It remains unclear whether the cardiovascular benefits reflect a direct reduction in atherogenic lipoproteins—namely, low‐density lipoproteins (LDL), very low‐density lipoproteins (VLDL) and
Andrea Baragetti, Giuseppe Danilo Norata
wiley   +1 more source

Sleep profiles in individuals with rare neurogenetic syndromes

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Aim To characterize sleep profiles in individuals with neurogenetic disorders (NGDs) and examine the contribution of key clinical and psychiatric symptoms to these profiles. Method The parents of 248 individuals (aged 3–45 years) diagnosed with a range of NGDs, including PTEN hamartoma tumor syndrome (n = 111), SYNGAP1‐related intellectual disability ...
Isabella C. Reyes   +7 more
wiley   +1 more source

Progression of Behavioral and CNS Deficits in a Viable Murine Model of Chronic Neuronopathic Gaucher Disease. [PDF]

open access: yesPLoS ONE, 2016
To study the neuronal deficits in neuronopathic Gaucher Disease (nGD), the chronological behavioral profiles and the age of onset of brain abnormalities were characterized in a chronic nGD mouse model (9V/null).
Mei Dai   +8 more
doaj   +1 more source

Genetic dissection reveals distinct contributions of the eS31 N‐terminal domain to translational accuracy in Saccharomyces cerevisiae

open access: yesThe FEBS Journal, EarlyView.
The eukaryote‐specific N‐terminal domain (NTD) of eS31 uses two distinct strategies to maintain translation fidelity. During elongation, a positively charged “hotspot” fine‐tunes the selection of incoming aa‐tRNA. During termination, the entire NTD acts as a structural scaffold to ensure the correct positioning of the release factor eRF1.
Qingxuan Gao   +3 more
wiley   +1 more source

Genetic diversity and population structure analysis of Ethiopian mustard (Brassica carinata A. Braun) accessions using simple sequence repeat markers

open access: yesAgrosystems, Geosciences &Environment, Volume 9, Issue 3, September 2026.
Abstract Brassica carinata A. Braun is an oilseed that originated in Ethiopia with a wide range of industrial and food applications. Exploring the genetic structure of the crop is crucial for breeding and conservation measures. Despite the fairly large number of B.
Abeba Yibrah   +3 more
wiley   +1 more source

Chronic Pain as an Early Diagnostic Clue in Hereditary Multiple Exostoses: Two Pediatric Cases Highlighting Diagnostic Delay

open access: yesClinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Hereditary multiple exostoses (HME) is a rare autosomal dominant skeletal disorder characterized by the development of multiple osteochondromas adjacent to the growth plates. Although skeletal deformities and palpable masses are common findings, chronic pain may represent an early and underappreciated diagnostic clue, particularly in pediatric
Melissa Mariti Fraga   +7 more
wiley   +1 more source

Natural gas demand prediction: comprehensive overview of the current situation and future development direction

open access: yesJournal of Pipeline Science and Engineering
Natural gas demand (NGD) forecasting can accurately estimate the gas demand, and help to plan the gas source configuration, pipeline network transportation and gas storage arrangements in advance, so as to achieve effective matching between supply and ...
Weibiao Qiao   +4 more
doaj   +1 more source

Evaluation of physical, chemical, and color‐matching properties of monochromatic resin composites: An in vitro study

open access: yesEuropean Journal of Oral Sciences, Volume 134, Issue 4, August 2026.
Abstract The objectives of this study are to evaluate, in vitro, the microhardness, sorption, solubility, color stability, and color‐matching ability of monochromatic resin composites: Palfique Omnichroma / Tokuyama (Mono1) and Vittra APS Unique / FGM (Mono2) compared with the conventional resin composite: Filtek Z250 XT / Solventum (Conv).
Ericka dos Santos Lopes   +5 more
wiley   +1 more source

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