Results 111 to 120 of about 933 (165)

TUSC3 serves as a rate-limiting gatekeeper of a glycan-mediated ER triage checkpoint for BMP4/Dpp. [PDF]

Cell Rep
Galeone A, Solazzo E, Lavezzari F, Han SY, Consonni G, My B, Rizzo R, Gigli G, Jafar-Nejad H, Vaccari T.   +9 more
europepmc   +1 more source

Using human pluripotent stem cell-based models to understand a congenital deglycosylation disorder-induced abnormality in cerebral development

, 2018
Research Appreciation Day Award Winner - 2018 Graduate School of Biomedical Sciences, Poster Presentation Award - 2nd PlaceBackground: Human pluripotent stem cells (hPSCs) provide significant promise for regenerative medicine and in addressing questions ...
Lin, Victor, Salick, Max, Hoffmann, Peter, Ho, Yin, Kayakas, Ajamete, Zolekar, Ashwini, Wang, Yu-chieh, Shakhbazau, Antos   +7 more
core  

Targeted long-read RNA sequencing for rare disease diagnosis and variant interpretation. [PDF]

Sci Adv
Wang R, Wang F, DeBruyne N, Ji X, Engelhardt NM, Park JJ, Notaro A, Gaerlan S, Park R, Schultz MJ, Clever S, McCormick EM, Keith K, Ng BG, Kadash-Edmondson KE, Freeze HH, Lam CT, Morava E, Helbig I, Falk MJ, Ganetzky RD, Edmondson AC, Lin L, Xing Y.   +23 more
europepmc   +1 more source

NFE2L1/Nrf1 forms a coactivator complex post-peptide:<i>N</i>-glycanase-mediated sequence editing and mitigates proteasome dysfunction. [PDF]

Proc Natl Acad Sci U S A
Yoshida Y, Okada M, Arai N, Ando C, Kinoshita D, Nishito Y, Kametani F, Hasegawa M, Tanaka K, Endo A.   +9 more
europepmc   +1 more source

Ubiquitin beyond the proteome: lipids, glycans, metabolites, nucleic acids, and an expanding molecular landscape. [PDF]

Biochem Soc Trans
Endo A, Yoshida Y.
europepmc   +1 more source

Erratum: [Erratum] Tofacitinib Improves Motor Symptoms in Parkinsonism Associated with a Heterozygous NGLY1 Variant and Autoimmune Disease. [PDF]

Eur J Case Rep Intern Med
Reina-Llompart N, Serrano-López S, Torres-Iglesias G, Álvarez-Troncoso J.   +3 more
europepmc   +1 more source

Comparative proteomics of HepG2 cells reveals NGLY1 as an important regulator of ferroptosis resistance and iron uptake. [PDF]

PLoS One
Emmerson S, Fujihira H, Suzuki T, Dohmae N, Greimel P, Hirabayashi Y, Suzuki T.   +6 more
europepmc   +1 more source

Taking the STING out of neurodegenerative disease. [PDF]

J Exp Med
Mangalmurti A, Lukens JR.
europepmc   +1 more source

Increased oxidative stress and autophagy in NGLY1 patient iPSC-derived neural stem cells. [PDF]

Exp Cell Res
Shyr ZA, Amniouel S, Owusu-Ansah K, Tambe M, Abbott J, Might M, Zheng W.   +6 more
europepmc   +1 more source

Structural characterization of zebrafish Ngly2, an ovary-enriched acid PNGase required for egg-free glycan production. [PDF]

J Biol Chem
Honda A, Kamada K, Seino J, Hirayama H, Fujihira H, Ueki M, Shiraki T, Burton-Smith RN, Murata K, Ishii N, Matsuo I, Suzuki T.   +11 more
europepmc   +1 more source