Results 61 to 70 of about 8,203 (206)

Efficacy and Skin Microbiome Modulation Effects of a Fixed-Concentration Combination of Benzoyl Peroxide 4% Plus Niacinamide 4% in a Film-Forming Cream in Subjects with Mild-to-Moderate Acne: A Non-Sponsored, Prospective, Assessor-Blinded, Pilot Trial

Cosmetics
Benzoyl peroxide (BPO) and niacinamide (Niac) are commonly used alone or in combination with other molecules in the treatment of acne. BPO and Niac in the same product could exert complementary and synergistic effects improving efficacy in acne ...
Mario Puviani, Klaus Eisendle
doaj   +1 more source

Delivery of Niacinamide to the Skin Using Microneedle-Like Particles

Pharmaceutics, 2019
The stratum corneum is the outermost skin layer that obstructs the delivery of active ingredients found in cosmeceutical products. Chemical peels and microbeads have been used to overcome this layer, but these methods can cause side effects and are not ...
Chong In Shin, MunSik Kim, Yeu-Chun Kim
doaj   +1 more source

Metabolic Regulation of Immune Responses: Molecular Mechanisms, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 6, June 2026.
FBP1 loss drives immune evasion and therapy resistance by enhancing glycolysis, STAT3 activation, and PD‐L1 expression, leading to T cell exhaustion and NK cell inhibition. FBP1 restoration, via LNP‐mRNA or epigenetic modulation, reverses these immunosuppressive effects, reactivates cytotoxic T cells, promotes M1 macrophage polarization, and enhances ...
Chunwei Li, Ziqiang Liu, Dezheng Kong, Zhengze Li, Yiming Yan, Yanyu Dong, Lili Zhu, JiaNing Cao, Zhirui Fan, Gautam Sethi, Lifeng Li   +10 more
wiley   +1 more source

The Harmful Trifecta of Skincare in African and Asian Populations: Triple Action Creams, Skin‐Lightening Creams, and Antiseptic Soaps

JEADV Clinical Practice, EarlyView.
Olufolakemi Cole‐Adeife, Monisha Madhumita, Doreen Mapunda, Daudi Mavura, Fatimata Ly   +4 more
wiley   +1 more source

Post‐Inflammatory Hyperpigmentation: Molecular Mechanisms and Advances in Dermocosmetic Management

Journal of Cosmetic Dermatology, Volume 25, Issue 6, June 2026.
ABSTRACT Background Post‐inflammatory hyperpigmentation (PIH) is a condition that causes skin pigmentation after acute or chronic inflammation. It affects people with darker skin tones more than others, especially Asians (Fitzpatrick types III–VI), and can last for months or even years, making life much less enjoyable.
Rui Li, Baiyu Li, Qilin Zhang, Chunyu Zhao, Caixia Ye, Yang Chen, Claire Huguet, Wei Xiong, Valentine Beguin, Delphine Kerob, Yijie Zheng   +10 more
wiley   +1 more source

Skin Boosters: 2026 Updated

Journal of Cosmetic Dermatology, Volume 25, Issue 6, June 2026.
ABSTRACT Skin boosters are increasingly used to improve dermal quality through injectable and device‐assisted approaches; however, definitions and clinical evidence remain heterogeneous. Aims To provide an updated overview and propose a practical classification of skin boosters, including mechanisms, delivery methods, clinical outcomes, and limitations.
Kyu‐ho Yi, Hyunggyu Kang, Jong Keun Song, Olena Sydorchuk, Jeremy B. Green, Hugues Cartier, Roya Zarmehr Zamin, Benjamin Ascher   +7 more
wiley   +1 more source

Examining the safety of nicotinamide for skin cancer prevention: Review of adverse events, metabolism, and toxic dosages

JAAD Reviews
Nicotinamide (niacinamide) supplementation for non-melanoma skin cancer prevention has sparked controversy over the past decade due to its inconsistent evidence of chemoprevention and its recently challenged safety profile.
Katie R. Xu, BA, Micah Belzberg, MD, Allison T. Vidimos, MD, RPh   +2 more
doaj   +1 more source

The Role of Nicotinamide in Cancer Chemoprevention and Therapy

Biomolecules, 2020
Nicotinamide (NAM) is a water-soluble form of Vitamin B3 (niacin) and a precursor of nicotinamide-adenine dinucleotide (NAD+) which regulates cellular energy metabolism.
Ilias P. Nikas, Stavroula A. Paschou, Han Suk Ryu   +2 more
doaj   +1 more source

Treatment of Acne‐Induced Facial Post‐Inflammatory Hyperpigmentation With a New 2‐MNG‐Containing Routine Versus a Thiamidol‐Containing Routine—A Monocentric Prospective Double‐Blind Randomized Comparative Trial

Journal of Cosmetic Dermatology, Volume 25, Issue 6, June 2026.
ABSTRACT Background Acne‐induced post‐inflammatory hyperpigmentation (PIHP) is a frequent condition. 2‐mercaptonicotinoyl glycine (2‐MNG) is an innovative anti‐pigmenting molecule. Aims The aim of this study is to compare the efficacy and tolerability of two routines in the treatment of PIHP: 2‐MNG‐containing serum + SPF50+/UVA sunscreen versus ...
Thierry Passeron, Guénaëlle Le Dantec, Samir Salah, Beatrice Marie, Kate Randamy, Kim T. F. C. Dhin‐Kien, Ann' Laure Demessant‐Flavigny, Andrew Alexis   +7 more
wiley   +1 more source

Niacinamide- Amino acids conjugates

, 2004
During this project we synthesized and characterized three new derivatives of niacinamide from drug to cosmetic ...
LANERI, SONIA, SACCHI, ANTONIA, OSTACOLO, CARMINE, Bernardi, Antonietta   +3 more
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