Results 101 to 110 of about 11,495 (257)

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Impacto de la NIC 41 en el Sector Agrícola Colombia

open access: yes, 2018
Globalization encompasses different aspects that force countries to redesign and implement measures, to face the evolution of financial, legislative, commercial fields and all those that interfere in the development and global organization; This is done for the purpose of being part of the systems of media communication systems. situations of the daily
openaire   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Minimising sunburn necrosis on Vitis vinifera L. ‘Riesling’ grapes by defoliation, photo- and thermal protection

open access: yesOENO One
Sunburn on grapes has emerged as an economic concern in recent decades. The phenomenon can be attributed to climatic changes, characterised by elevated air temperatures and intense solar radiation, leading to increased crop failures as well as quality ...
Jonas Waber   +15 more
doaj   +1 more source

Evaluación de activos porcinos en Ecuador: impacto pre y post Covid-19 bajo la NIC 41

open access: yesYachana Revista Científica
Este estudio analiza la valoración de activos biológicos en la producción porcina en Ecuador y destaca la falta de formalidad en la administración y contabilidad. A pesar de la NIC 41, los métodos de valoración no están estandarizados. Se revela un mercado activo y, a la vez, se identifica una oportunidad para contadores profesionales.
Maritza Galarza-Alay   +1 more
openaire   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Sistema contable de los activos biológicos y aplicación NIC 41

open access: yes, 2017
Con la implementación en Colombia de las NIIF mediante la promulgación de la Ley 1314 de 2009, se incorpora la Norma Internacional de Contabilidad 41 (NIC 41) la cual establece una ruta de guía contable de cómo deben estar presentados los estados financieros en la actividad agrícola, teniendo en cuenta que la trasformación biológica de animales vivos o
openaire   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Reconocimiento y medición de activos forestales en un modelo contable prospectivo. Valor razonable como medida de beneficios económicos futuros según marco conceptual para la información financiera, NIIF 13 Y NIC 41 (PARTE 1)

open access: yesContabilidad y Auditoría, 2016
Los activos forestales son bienes donde la metodología utilizada para su medición y revelación contable es esencialmente elaborada bajo un modelo de información financiera prospectiva.
Andrés Alberto Mancini
doaj  

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