Results 111 to 120 of about 11,890 (257)
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Sunburn on grapes has emerged as an economic concern in recent decades. The phenomenon can be attributed to climatic changes, characterised by elevated air temperatures and intense solar radiation, leading to increased crop failures as well as quality ...
Jonas Waber +15 more
doaj +1 more source
Sistema contable de los activos biológicos y aplicación NIC 41
Con la implementación en Colombia de las NIIF mediante la promulgación de la Ley 1314 de 2009, se incorpora la Norma Internacional de Contabilidad 41 (NIC 41) la cual establece una ruta de guía contable de cómo deben estar presentados los estados financieros en la actividad agrícola, teniendo en cuenta que la trasformación biológica de animales vivos o
openaire +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Los activos forestales son bienes donde la metodología utilizada para su medición y revelación contable es esencialmente elaborada bajo un modelo de información financiera prospectiva.
Andrés Alberto Mancini
doaj
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Factores de riesgo en mujeres con citología anormal
Se realizó un estudio descriptivo transversal con el objetivo de caracterizar los factores de riesgos asociados con citologías anormales en mujeres del Municipio Acevedo, del Estado Miranda, Venezuela, durante el periodo de noviembre de 2008 y ...
Misladys Baldemira Álvarez +3 more
doaj
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source

