Results 131 to 140 of about 11,890 (257)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Surgery versus radiotherapy after neoadjuvant immunochemotherapy in limited-stage small cell lung cancer. [PDF]

J Thorac Dis
Zou R, Zhu Z, Teng X, Yu S, Lyu X.
europepmc   +1 more source

Análisis de la Norma Internacional de Contabilidad 41 (NIC 41-activos biológicos) en las empresas florícolas ubicadas en el cantón Mejía año 2019.

, 2021
El presente trabajo de investigación que tiene por objetivo determinar la fidelidad del valor razonable que tienen las acciones empresariales de las florícolas ubicadas en el Cantón Mejía, y su cumplimiento con los planteamientos de la NIC 41 se lo lleva a cabo a través de una metodología cuantitativa a partir de la cual se da cabida al desarrollo de ...
openaire   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Efficacy and Safety of Nicotinamide 10%, Associated with Magnesium Ascorbyl Phosphate 5% and Hyaluronic Acid 5%, Compared to Hydroquinone 4% in Women with Facial Melasma: A Randomized, Double-Blind, Controlled Clinical Trial.

Clinical, Cosmetic and Investigational Dermatology
Mayla Barbosa,1 Rebecca Perez de Amorim,1 Daniel Cassiano,2 Marina Dias,1 Ana Flávia de Abreu,1 Edileia Bagatin,2 Hélio Amante Miot,1 Ana Cláudia Cavalcante Espósito1 1Department of Dermatology, Faculdade de Medicina de Botucatu (UNESP), Botucatu, SP ...
Barbosa M, de Amorim RP, Cassiano D, Dias M, de Abreu AF, Bagatin E, Miot HA, Espósito ACC   +7 more
doaj  

Spectral CT iodine quantification for peritoneal metastasis burden and resectability prediction in ovarian cancer: a retrospective cohort study. [PDF]

Front Oncol
Liu Y, Wu X, Deng H, Lin Y, Lin M.
europepmc   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Intracranial Pressure Monitoring, Heart Rate Variability, Baroreflex Sensitivity, and Signal Complexity During Neurointensive Care after Decompressive Craniectomy in Malignant Middle Cerebral Artery Infarction. [PDF]

Neurocrit Care
Alhamdan M, Hånell A, Howells T, Joensen O, Velle F, Lewén A, Enblad P, Svedung Wettervik T.   +7 more
europepmc   +1 more source