Results 151 to 160 of about 286,454 (285)
El Acercamiento de la normativa contable europea a las normas del IASB: un reto para 2005
Contabilidad y Auditoría, 2012 Actualmente es de aceptación generalizada la necesidad de un lenguaje contable común. La creciente e imparable globalización de las relaciones económicas y financieras exige disponer de una información comparable, objetiva, transparente y fiable, lo cual
Julita Garcia Diez +1 more
doaj
Metodología para la aplicación de la NIC 41 a la producción del sector porcino del cantón La Mana
Revista Científica Arbitrada Multidisciplinaria PENTACIENCIASLa producción porcina en el cantón La Maná es vital tanto económica como socialmente, ofreciendo alimentos esenciales y beneficiándose de ventajas competitivas como su ubicación, suelo favorable y bajos costos productivos. La industria busca producir carne de calidad para satisfacer la demanda nacional a precios accesibles, mejorando técnicas y ...
Jessica Llanqui Toaquiza +3 more
openaire +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Brončanodobni nalazi iz karlovačke regije
Arheološki Vestnik, 1989 arcfiif. Karlovac-Region befindet sich um das zentrale Flufigebiet des Flusses Kupa. Vom Cf°l°gischen Gesichtspunkt aus ist dieser Raum ungeniigend erforscht worden. Uber die V d l U n d Mittelbronzezeit herrschen nach wie vor Unklarheiten.
Lazo Čučković
doaj
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source