Results 201 to 210 of about 38,445 (262)

A Circuit of Mechanically Regulated Transcription Factors Balances Regenerative and Fibrotic Memory of Mesenchymal Stromal Cells

Advanced Science, EarlyView.
Producing MSCs on rigid culture substrates induces a scar‐making phenotype, jeapordizing therapeutic success. ‘Tissue‐soft’ surfaces prevent MSC fibrogenesis and preserve regenerative traits. An epigenetic network, driven by HOXA11 and SALL1, maintains ‘soft memory’ by keeping chromatin open in relaxed MSCs, promoting anti‐fibrotic programs.
Fereshteh Sadat Younesi, Andrew E. Miller, Li Diao, Xinying Guo, Natalie Andonian, Elham Karimizadeh, Thomas H. Barker, Boris Hinz   +7 more
wiley   +1 more source

Phylogeography and Population Demography of <i>Parrotia subaequalis</i>, a Hamamelidaceous Tertiary Relict 'Living Fossil' Tree Endemic to East Asia Refugia: Implications from Molecular Data and Ecological Niche Modeling. [PDF]

Plants (Basel)
Zhang Y, Li Z, Chen Q, Wang Y, Wang S, Wang G, Li P, Liu H, Li P, Xu C, Wang Z.   +10 more
europepmc   +1 more source

Adult Sex Ratio as a Demographic Feedback Linking Mating Systems, Parental Care, and Evolution

Advanced Science, EarlyView.
Breeding systems are some of the most diverse social behavior, and our team is investigation the evolutionary causes of this diversity. This review summarises our research carried out at the University of Bath. We argue that demographic components of wild populations, especially the adult sex ratio, plays a key role driving breeding system variation ...
Tamás Székely, Oscar G. Miranda
wiley   +1 more source

Downscaling air temperatures for high-resolution niche modeling in a valley of the Amazon lowland forests: A case study on the microclima R package. [PDF]

PLoS One
Pohl MJ, Lehnert L, Thies B, Seeger K, Berdugo MB, Gradstein SR, Bader MY, Bendix J.   +7 more
europepmc   +1 more source

Aptamer‐Engineered Liposomal Platform Enables in Situ cDC1 Vaccination to Potentiate Immunotherapy in Prostate Cancer

Advanced Science, EarlyView.
Prostate cancer is immunologically ‘cold’, with scarce, dysfunctional type 1 conventional dendritic cells (cDC1s) that limit T cell priming. We introduce an aptamer‐targeted liposomedelivering FMS‐like tyrosine kinase 3 ligand (Flt3L) and chlorin e6 (Ce6). Ultrasound induces antigen release and cDC1s recruitment, creating an in situ cDC1 vaccine.
Jiayi Wang, Xuan Wang, Xinfeng Dai, Linxin Tian, Wencheng Shen, Xueliang Liu, Wei Xue, Jiahua Pan, Yu Yang   +8 more
wiley   +1 more source

Grass species with potential for rangelands restoration in northern Mexico: an assessment with environmental niche modeling. [PDF]

Sci Rep
Álvarez-Holguín A, Morales-Nieto CR, Corrales-Lerma R, Ochoa-Rivero JM, Ponce-García OC, Prieto-Amparán JA, Vega-Mares JH, Villarreal-Guerrero F.   +7 more
europepmc   +1 more source

Traction Force Microscopy for Viscoelastic Substrates: A Semi‐Analytical Method

Advanced Science, EarlyView.
A semi‐analytical viscoelastic traction force microscopy framework is introduced for quantifying time‐resolved cell tractions on flat finite‐thickness substrates. The method generalizes elastic traction force microscopy to Generalized Maxwell materials, identifies when elastic approximations remain valid and, when they do not, shows that inferred ...
Adrià Villacrosa‐Ribas, Daniëlle C. A. Duffhues, Pim van den Bersselaar, Sarah Pragnere, Bart G. W. Groenen, Mariana Azevedo Gonzalez Oliva, Giuseppe Ciccone, Manuel Salmeron‐Sanchez, Carlijn V. C. Bouten, Jose J. Muñoz, Vito Conte   +10 more
wiley   +1 more source

Conservation applications of niche modeling: Native and naturalized ferns may compete for limited Hawaiian dryland habitat. [PDF]

Appl Plant Sci
Edwards-Calma K, Jiménez L, Zenil-Ferguson R, Heyduk K, Thomas MK, Tribble CM.   +5 more
europepmc   +1 more source

Two Routes to Land: Genomic Underpinnings of Parallel Aerial Egg Deposition in Aquatic Old‐World Pila and New‐World Pomacea (Ampullariidae)

Advanced Science, EarlyView.
Comparative genomics of Gondwana‐diverged Pila and Pomacea reveals parallel evolution of aerial oviposition. Convergent chromosomal rearrangements reshape regulatory landscapes within topologically associating domains. Lineage‐specific gene family expansions and viral‐derived perivitelline proteins (PV1) underpin desiccation resistance.
Yufei Zhou, Huawei Mu, Xueying Nie, Yue Gao, Hui Wang, Ling Fang, Tiangang Luan, Monthon Ganmanee, Jian‐Wen Qiu, Jin Sun, Jack Chi‐Ho Ip   +10 more
wiley   +1 more source

Genetic diversity, population structure and ecological niche modeling of Thyrinteina arnobia (Lepidoptera: Geometridae), a native Eucalyptus pest in Brazil. [PDF]

Sci Rep
Nanini F, Souza PGC, Soliman EP, Zauza EAV, Domingues MM, Santos FA, Wilcken CF, da Silva RS, Corrêa AS.   +8 more
europepmc   +1 more source