Results 51 to 60 of about 38,445 (262)

Modeling Habitat Suitability for Endemic Anthemis pedunculata subsp. pedunculata and Anthemis pedunculata subsp. atlantica in Mediterranean Region Using MaxEnt and GIS-Based Analysis

Diversity
Climate change accelerates biodiversity loss, threatening ecosystems worldwide. Using predictive models, such as the maximum entropy model (Maxent), allows us to identify changes in species distribution and guide conservation strategies.
Kaouther Mechergui, Wahbi Jaouadi, Carlos Henrique Souto Azevedo, Khadeijah Yahya Faqeih, Somayah Moshrif Alamri, Eman Rafi Alamery, Maha Abdullah Aldubehi, Philipe Guilherme Corcino Souza   +7 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Biogeography and environmental preferences of Butia yatay (Mart.) Becc

Ecology and Evolution, 2023
During the Quaternary, Chaco Phytogeographic Domain (Chaco) flora in subtropical South America experienced temperature and humidity fluctuations, primarily driven by wind dynamics, leading to significant shifts in species distribution.
G. Carolina Silva, Viviana Griselda Solís Neffa, Gabriela Zuquim, Henrik Balslev   +3 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Effects of future climate change on the geographical distribution of a bird endemic to South American floodplains

Avian Conservation and Ecology, 2021
Future climate change poses an immediate threat to biodiversity. Species are shifting their geographic distribution in direct response to climate change. Species around the globe are expected to redistribute poleward and/or to high elevations.
Mayara F. Zucchetto, Natalia S. Da Silveira, Victor M. Prasniewski, Tatiane Arnhold, Thadeu Sobral-Souza, João B. de Pinho   +5 more
doaj  

Spatio-Temporal Patterns of Climatic Niche Dynamics of an Invasive Plant Mikania micrantha Kunth and Its Potential Distribution Under Projected Climate Change

Frontiers in Ecology and Evolution, 2019
Similarity of climatic niches occupied by a species in its native and invasive ranges has been recognized as one of the key factors for successful invasion.
Achyut Kumar Banerjee, Abhishek Mukherjee, Wuxia Guo, Ying Liu, Yelin Huang   +4 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

The edaphic niche of ploidy-different grasses in the light of the coarse-grained data modeling and direct soil sampling

Ecological Indicators
In the framework of polyploidization, a widely discussed issue is the possibility of niche shift. Numerous studies have investigated niche differentiation among cytotypes, with some confirming distinct differences, while others finding them to be similar.
Katarzyna M. Zielińska, Marcin Kiedrzyński, Wojciech Tołoczko, Edyta Kiedrzyńska, Monika Mętrak   +4 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Ecological niche modelling

Current Biology
One of the central research questions in ecology and biogeography revolves around understanding the spatial distribution patterns of organisms, the factors influencing species abundance, and why in certain areas there are more species or individuals than in others.
openaire   +3 more sources