Results 151 to 160 of about 256,874 (388)

Does the Supramolecular Complexation of Polyphenolic Acids with the Isomers of Pyridinecarboxamide Affect Their Antiradical Activity?

Applied Sciences
Polyphenolic compounds are considered one as the most important plant-originated species with antioxidant properties. This paper focuses on exploring the structure and antiradical properties of supramolecular complexes derived from the selected ...
Małgorzata Olszowy-Tomczyk, Justyna Sienkiewicz-Gromiuk   +1 more
doaj   +1 more source

Nicotinamide Deficiency in Primary Open-Angle Glaucoma

bioRxiv, 2019
PURPOSE To investigate the plasma concentration of nicotinamide in primary open-angle glaucoma (POAG). DESIGN Case-control study METHODS Plasma of 34 POAG individuals were compared to that of 30 age- and sex-matched controls using a semi-quantitative ...
J. K. Nzoughet, Juan Manuel Chao de la Barca, Khadidja Guehlouz, S. Leruez, L. Coulbault, S. Allouche, C. Bocca, J. Muller, P. Amati‐Bonneau, P. Gohier, D. Bonneau, G. Simard, D. Milea, G. Lenaers, V. Procaccio, P. Reynier   +15 more
semanticscholar   +1 more source

A Longitudinal Study Reveals Metabolomic Markers for Individuals at Risk, Disease Severity, and Treatment Response in Rheumatoid Arthritis

Advanced Science, EarlyView.
This study investigates plasma metabolomic biomarkers for rheumatoid arthritis (RA) development using longitudinal data from 209 RA patients and 56 individuals at risk. It also reveals metabolic signatures linked to severity, age, sex, and anti‐citrullinated protein autoantibody in RA.
Chenxi Zhu, Jiayi Xu, Siyu He, Qian Niu, Yi Liu, Xin Guo, Huifang Hu, Rui Sun, Tao Chen, Yan Liu, Zhiqiang Xu, Na Jiang, Lipu Yao, Lunzhi Dai, Qinghua Zou, Fanxin Zeng, Liesu Meng, Inger Gjertsson, Rikard Holmdahl, Bin Yang, Dan Du, Yi Zhao   +21 more
wiley   +1 more source

Is sensitization with nicotinamide and carbogen dependent on nicotinamide concentration at the time of irradiation?

International Journal of Radiation Biology, 2004
To determine whether tumour radiosensitization and the therapeutic benefit of administering carbogen with nicotinamide depend upon irradiating at the time of peak drug concentration.Local tumour control of CaNT tumours in CBA mice and acute skin reactions in albino WHT mice were assessed after treatment with 10 X-ray fractions in air, carbogen alone or
Rojas, A, Stratford, MR, Bentzen, S, Denekamp, J   +3 more
openaire   +4 more sources

Intestinal Clock Promotes Cognitive Memory Through Adenosine Signaling

Advanced Science, EarlyView.
The intestinal clock controls the expression of an adenosine enzyme that modulates systemic adenosine level and A1R signaling in the hippocampus, and in turn, cognitive function involving long‐term potentiation and BDNF‐dependent synaptic changes.
Min Chen, Fugui Zhang, Yifei Xiao, Xuejun Jiang, Zhiqian Yan, Jinyi Wang, Xiting Lv, Jialu Cui, Linna Ha, Hui Chen, Yongkang Dang, Zifei Qin, Jing Yang, Baojian Wu   +13 more
wiley   +1 more source

Nicotinamide mononucleotide (NMN) as an anti-aging health product – Promises and safety concerns

Journal of Advanced Research, 2021
Harshani Nadeeshani, Jinyao Li, T. Ying, Baohong Zhang, Jun Lu   +4 more
semanticscholar   +1 more source

Covalent Organic Frameworks‐Delivered Reuterin Drives Trained Immunity in Tumor‐Associated Macrophages to Enhance Melanoma Immunotherapy via Glycerophospholipid Metabolism

Advanced Science, EarlyView.
Covalent organic framework (COF)‐reuterin induces trained immunity in tumor‐associated macrophages, promoting the generation of nitric oxide and reactive oxygen species, thereby enhancing the antitumor immune response. Additionally, COF‐Reuterin directly kills tumor cells while simultaneously eradicating pathogenic intratumoural bacteria.
Jian‐Gang Zhang, Xiao‐Mei Zhang, Xi Wu, Cheng‐Kai Zhou, Zhen‐Zhen Liu, Xue‐Yue Luo, Liang Zhang, Wei Chen, Yong‐Jun Yang   +8 more
wiley   +1 more source

Developing Biomaterial‐Based mRNA Delivery System for Lung Disease Treatment

Advanced Science, EarlyView.
Schematic illustration of biomaterial delivery mRNA for the treatment of lung diseases. Abstract Lung disease remains a persistent global health challenge. Advances in medical research have led to innovative strategies to combat these conditions, with biomaterials emerging as a promising platform for targeted drug delivery.
Qiancheng Gu, Huaqian Xue, Zhiyun Liu, Jiameng Rao, Lingyao Zeng, Chen Zhang, Lanjie Lei, Liyun Shi   +7 more
wiley   +1 more source

Regulation of Peripheral Molecular Clocks in Mammalian Tissues and In Vitro Skeletal Muscle Activation of AMP-Activated Protein Kinase via AICAR

, 2014
Most organisms possess a common molecular machinery that governs cellular and tissue circadian rhythmicity through a roughly 24-hour transcription-translation feedback loop.
Brandauer, Josef, Lupolt, Alex C., Moorhead, Daniel P.   +2 more
core  

Accelerated and efficient neuronal differentiation of Sox1GFP mouse embryonic stem cells in vitro using nicotinamide [PDF]

, 2014
A major challenge for advancement of clinical neuronal replacement therapies is the production of high yields of purified neuronal populations of appropriate phenotype with control over proliferation to prevent tumorigenesis.
Fricker, Rosemary, Griffin, Sile, Pickard, Mark R.   +2 more
core