Results 201 to 210 of about 134,103 (347)

Investigating the role of SARM1 in central nervous system

open access: yesIbrain, EarlyView.
Sterile‐α and Toll/interleukin 1 receptor (TIR) motif‐containing protein 1 (SARM1) is a pivotal molecule that has garnered extensive attention in neuroscience. As an intracellular molecule, SARM1 possesses various crucial biological functions in the nervous system.
Junjie Wang   +4 more
wiley   +1 more source

Targeting aerobic glycolysis combats tyrosine kinase inhibitor resistance of hepatocellular carcinoma

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Hepatocellular carcinoma (HCC) represents the predominant form of primary liver cancer and is frequently identified at a late stage, necessitating systemic therapy. However, resistance to first‐line tyrosine kinase inhibitor therapies, such as sorafenib and lenvatinib, remains a significant clinical challenge.
Longtao Zhao   +6 more
wiley   +1 more source

Nicotinamide adenine dinucleotide rejuvenates septic bone marrow mesenchymal stem cells. [PDF]

open access: yesWorld J Stem Cells
Xia X   +7 more
europepmc   +1 more source

Nicotinamide Adenine Dinucleotide Phosphate Oxidase Promotes Glioblastoma Radiation Resistance in a Phosphate and Tensin Homolog-Dependent Manner. [PDF]

open access: yesAntioxid Redox Signal, 2023
Ludwig K   +7 more
europepmc   +1 more source

Alterations and mechanistic insights of gut microbiota and its metabolites in type 2 diabetes mellitus and Alzheimer's disease

open access: yesiMetaOmics, EarlyView.
This narrative review uniquely addresses how gut microbiota‐derived metabolites mediate overlapping pathologies of insulin resistance, neuroinflammation, and amyloidogenesis in type 2 diabetes mellitus (T2DM) and Alzheimer's disease (AD), proposing a framework for dual therapeutic targeting.
Guangyi Xu   +8 more
wiley   +1 more source

Metabolic profiles of cutaneous lupus have abnormalities in the nicotinamide adenine dinucleotide pathway. [PDF]

open access: yesLupus Sci Med
Abbas LF   +9 more
europepmc   +1 more source

Advances in the study of nicotinamide adenine dinucleotide phosphate oxidase in myocardial remodeling. [PDF]

open access: yesFront Cardiovasc Med, 2022
Miao R   +11 more
europepmc   +1 more source

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