Results 241 to 250 of about 121,735 (279)
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Recycling analysis of nicotinamide-adenine dinucleotide phosphates (NADP and NADPH)
Analytical Biochemistry, 1979A simple and sensitive analysis of NADP and NADPH is described. It uses the glucose-6-phosphate dehydrogenase-glutathione reductase system with detection of reduced glutathione through reaction with 5,5′-dithiobis(2-nitrobenzoic acid), Ellmans reagent. The rate of reaction is constant for several hours, and the analytical system does not react with NAD
Bo Jørgensen, Hans Rasmussen
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Oxidation of reduced nicotinamide adenine dinucleotide phosphate by plant mitochondria
Canadian Journal of Biochemistry, 1979Mitochondria isolated from various plant tissues (leaves, etiolated shoots and hypocotyls, and stem tubers) oxidize exogenous NADPH with respiratory control values and ADP:O ratios similar to those obtained with exogenous NADH as substrate. In all the mitochondria investigated, the electron-transfer inhibitors rotenone and amytal each had the same ...
Geoffrey P. Arron, Gerald E. Edwards
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Identification of a stable complex of trichosanthin with nicotinamide adenine dinucleotide phosphate
Journal of Protein Chemistry, 1995Trichosanthin, a type I ribosome-inactivating protein with RNA N-glycosidase activity, forms a stable complex with nicotinamide adenine dinucleotide phosphate, a substrate analog. Difference UV spectroscopy, fluorescence spectroscopy, and 31P NMR are used to identify the formation of the complex, followed by a crystal structure analysis carried out to ...
Yu Wang, Zong-Xiang Xia, Jain-Ping Xiong
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Enzymatic cyclization of nicotinamide adenine dinucleotide phosphate (NADP)
Bioorganic & Medicinal Chemistry Letters, 1995Abstract The ADP-ribosyl cyclase of Aplysia californica catalyzed the conversion of NADP, 3′-NADP and 2′,3′-cyclic NADP into their corresponding cyclic nucleotides (established by NMR, UV, and MS analyses). Cyclic-ADP-ribose-phosphate (cADPRP) was more potent than cADPR in mobilizing calcium in the rat brain microsomal system; the EC50 for cADPRP and
Charles J. Sih +3 more
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Nicotinamide Adenine Dinucleotide Phosphate Oxidase in the Formation of Superoxide in Osteoclasts
Calcified Tissue International, 1998Osteoclasts use a variety of chemical agents to degrade bone. One important component of this process is the generation of superoxide. It has been reported that nicotinamide adenine dinucleotide phosphate (NADPH) oxidase is the enzyme responsible for superoxide production in phagocyte; however, the NADPH oxidase present in osteoclasts has not been ...
Su Yang, William L. Ries, L. L. Key
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Nicotinamide adenine dinucleotide phosphate-specific dehydrogenases in relation to lipogenesis
Biochimica et Biophysica Acta (BBA) - Specialized Section on Lipids and Related Subjects, 1964Abstract The NADP-dependent malate dehydrogenase (decarboxylating) ( l -malate: NADP oxidoreductase (decarboxylating) EC 1.1.1.40), combined hexose monophosphate shunt dehydrogenases∗ and isocitrate dehydrogenase ( l S-isocitrat: NADP oxido-reductase (decarboxylating), EC 1.1.1.42) activities were assayed in mitochondrion-free fractions of liver ...
R. Parvin Khan +2 more
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The Role of Nicotinamide Adenine Dinucleotide Phosphate Oxidase in the Pathogenesis of Hypertension
High Blood Pressure & Cardiovascular Prevention, 2009Oxidative stress is believed to play a crucial role in the initiation and progression of atherosclerosis. In particular, oxidative stress could be involved in the pathogenesis of hypertension but, until now, there is still a debate whether oxidative stress is a cause or a result of hypertension.
LOFFREDO, Lorenzo, VIOLI, Francesco
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Composition and Functions of Vascular Nicotinamide Adenine Dinucleotide Phosphate Oxidases
Trends in Cardiovascular Medicine, 2008Nicotinamide adenine dinucleotide phosphate (NADPH) oxidases are important sources of reactive oxygen species (ROS) and are expressed in at least three different homologues in the vasculature. The enzymes consist of a membrane complex of one of the large catalytically active Nox proteins and p22phox and different cytosolic subunits.
Ralf P. Brandes, Katrin Schröder
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Canadian Journal of Microbiology, 1982
Fragility of rabbit erythrocytes in agar plates results in gradual release of their NAD and NADP contents into the medium. Due to high NADase and negligible NADPase activity of rabbit red blood cell stroma at neutral pH, the NAD released into the medium is hydrolyzed and NADP remains intact.
M. Artman, G. Frankl
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Fragility of rabbit erythrocytes in agar plates results in gradual release of their NAD and NADP contents into the medium. Due to high NADase and negligible NADPase activity of rabbit red blood cell stroma at neutral pH, the NAD released into the medium is hydrolyzed and NADP remains intact.
M. Artman, G. Frankl
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Nicotinamide Adenine Dinucleotide Phosphate Oxidase and Diabetes: Vascular Implications
Vascular and Endovascular Surgery, 2008Vascular disease associated with diabetes mellitus is a major cause of morbidity and mortality and is increasing in the United States. It is now recognized that oxidative stress plays a substantial role in the underlying vascular pathology of several diseases, including hypertension and diabetes.
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