Results 21 to 30 of about 121,735 (279)

Niacin – a scoping review for Nordic Nutrition Recommendations 2023

open access: yesFood & Nutrition Research, 2023
Niacin is the precursor to pyridine nucleotides NAD (nicotinamide adenine dinucleotide) and NADP (nicotinamide adenine dinucleotide phosphate). Niacin (vitamin B3) is the common term for nicotinic acid, nicotinamide and derivatives that exhibit the ...
Riitta Freese, Vegard Lysne
doaj   +1 more source

Enzymology of Ca2+-Mobilizing Second Messengers Derived from NAD: From NAD Glycohydrolases to (Dual) NADPH Oxidases

open access: yesCells, 2023
Nicotinamide adenine dinucleotide (NAD) and its 2′-phosphorylated cousin NADP are precursors for the enzymatic formation of the Ca2+-mobilizing second messengers adenosine diphosphoribose (ADPR), 2′-deoxy-ADPR, cyclic ADPR, and nicotinic acid adenine ...
Andreas H. Guse
doaj   +1 more source

TNB-738, a biparatopic antibody, boosts intracellular NAD+ by inhibiting CD38 ecto-enzyme activity

open access: yesmAbs, 2022
Cluster of differentiation 38 (CD38) is an ecto-enzyme expressed primarily on immune cells that metabolizes nicotinamide adenine dinucleotide (NAD+) to adenosine diphosphate ribose or cyclic ADP-ribose and nicotinamide.
Harshad S. Ugamraj   +19 more
doaj   +1 more source

Electron-Accepting Micelles Deplete Reduced Nicotinamide Adenine Dinucleotide Phosphate and Impair Two Antioxidant Cascades for Ferroptosis-Induced Tumor Eradication.

open access: yesACS Nano, 2020
Ferroptotic antitumor therapy has been compromised by various intracellular antioxidants, particularly glutathione and thioredoxin. Both are cofactors of glutathione peroxide 4 (GPX4) that act against oxidative stress via catalyzing the reduction of ...
Xuliang Guo   +9 more
semanticscholar   +1 more source

Enzymatic reduction of nicotinamide adenine dinucleotide phosphate induced by radiolysis

open access: hybridJournal of Biological Chemistry, 1975
Shu Chan   +4 more
openalex   +4 more sources

Hydrophilic Tetraphenylethene-Based Tetracationic Cyclophanes: NADPH Recognition and Cell Imaging With Fluorescent Switch

open access: yesFrontiers in Chemistry, 2021
A hydrophilic TPE-based tetracationic cyclophane TPE-cyc was synthesized, which could capture intracellular Nicotinamide adenine dinucleotide phosphate and fuel the antioxidative ability of tumor cells to detoxify reactive oxygen species (ROS). Meanwhile,
Dan Wu   +4 more
doaj   +1 more source

Metabolic Profiling of Human Gastric Cancer Cells Treated With Salazosulfapyridine

open access: yesTechnology in Cancer Research & Treatment, 2020
Purpose: The adhesion molecule cluster of differentiation 44v9 interacts with and stabilizes the cystine/glutamate exchanger protein, which functions as a transporter of cystine.
Kohei Takizawa MD   +8 more
doaj   +1 more source

Angiotensin II and NADPH Oxidase Increase ADMA in Vascular Smooth Muscle Cells [PDF]

open access: yes, 2010
Asymmetric dimethylarginine inhibits nitric oxide synthase, cationic amino acid transport and endothelial function. Patients with cardiovascular risk factors often have endothelial dysfunction associated with increased plasma asymmetric dimethylarginine ...
Aslam, S.   +5 more
core   +5 more sources

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