Results 301 to 310 of about 107,918 (341)

MicroRNA Targeting Nicotinamide Adenine Dinucleotide Phosphate Oxidases in Cancer

Antioxidants & Redox Signaling, 2020
Significance: Reactive oxygen species (ROS) production occurs primarily in the mitochondria as a by-product of cellular metabolism. ROS are also produced by nicotinamide adenine dinucleotide phosphate (NADPH) oxidases in response to growth factors and cytokines by normal physiological signaling pathways.
Prem Prakash, Kushwaha, Sanjay, Gupta, Atul Kumar, Singh, Kumari Sunita, Prajapati, Mohd, Shuaib, Shashank, Kumar   +5 more
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Liquid chromatographic separations of dimers of nicotinamide adenine dinucleotide and nicotinamide adenine dinucleotide phosphate

Journal of Chromatography A, 1985
Abstract The dimers of nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phosphate (NADP) [(NAD)2 and (NADP)2, respectively[ were prepared electrolytically from NAD and NADP and analysed by several chromatographic techniques. Gel permeation chromatography on UltroPac columns was more convenient for the separation of dimers
J. Kova´rˇ, J. Tura´nek, C. Hlava´cˇ, V. Vala, V. Kahle   +4 more
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Thermodynamics of Reactions of Nicotinamide Adenine Dinucleotide and Nicotinamide Adenine Dinucleotide Phosphate

Archives of Biochemistry and Biophysics, 1993
The thermodynamics of six reactions of nicotinamide adenine dinucleotide and nicotinamide adenine dinucleotide phosphate is discussed both from the viewpoint of the chemical equations and the biochemical equations for these reactions. Tables of the standard enthalpies of formation and standard Gibbs energies of formation of species are presented and ...
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Regulation of nicotinamide adenine dinucleotide phosphate levels in yeast

Archives of Biochemistry and Biophysics, 1977
Abstract The steady-state levels and redox states of pyridine nucleotide pools have been studied in yeast as a function of external growth conditions. Yeast grown aerobically on 0.8% glucose show two distinct phases of logarithmic growth, a first phase utilizing glucose with ethanol accumulation, and a second phase utilizing ethanol. During growth on
H Y, Ting, L, Jacobson, M K, Jacobson
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An improved enzymatic cycle for nicotinamide-adenine dinucleotide phosphate

Analytical Biochemistry, 1978
Abstract An enzymatic cycling reagent for NADP is described which is capable of amplifying 100,000-fold in 4 hr at 38°C or 350,000-fold in 3 days at 15°C. The improvement over a previously described reagent results from several changes, the most important of which is substitution of glucose-6-P dehydrogenase from Leuconostoc mesenteroides for the ...
M M, Chi, C V, Lowry, O H, Lowry
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Determination of nicotinamide-adenine dinucleotide phosphate in blood

Clinica Chimica Acta, 1965
Abstract A method for the determination of nicotinamide-adenine dinucleotide phosphate present as the oxidised (NADP) and reduced (NADPH2) forms m blood is described. The coenzyme is extracted from blood and allowed to participate in reactions involving the oxidation of malate to pyruvate and reduction of oxidised glutathione (GSSG) to reduced ...
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Capillary electrophoresis of nicotinamide—adenine dinucleotide and nicotinamide—adenine dinucleotide phosphate derivatives in coated tubular columns

Journal of Chromatography A, 1994
Abstract HPCE was shown to be an effective and convenient method for the determination of nicotinamide—adenine dinucleotide (oxidized, NAD + ; reduced, NADH), nicotinamide—adenine dinucleotide phosphate (oxidized, NADP; reduced, NADPH) and their synthetic derivatives.
Marina Nesi, Marcella Chiari, Giacomo Carrea, Gianluca Ottolina, Pier Giorgio Righetti   +4 more
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Enzymatic cyclization of nicotinamide adenine dinucleotide phosphate (NADP)

Bioorganic & Medicinal Chemistry Letters, 1995
Abstract The ADP-ribosyl cyclase of Aplysia californica catalyzed the conversion of NADP, 3′-NADP and 2′,3′-cyclic NADP into their corresponding cyclic nucleotides (established by NMR, UV, and MS analyses). Cyclic-ADP-ribose-phosphate (cADPRP) was more potent than cADPR in mobilizing calcium in the rat brain microsomal system; the EC50 for cADPRP and
Fang-Jie Zhang, Qu-Ming Gu, Peicheng Jing, Charles J. Sih   +3 more
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Recycling analysis of nicotinamide-adenine dinucleotide phosphates (NADP and NADPH)

Analytical Biochemistry, 1979
A simple and sensitive analysis of NADP and NADPH is described. It uses the glucose-6-phosphate dehydrogenase-glutathione reductase system with detection of reduced glutathione through reaction with 5,5′-dithiobis(2-nitrobenzoic acid), Ellmans reagent. The rate of reaction is constant for several hours, and the analytical system does not react with NAD
B M, Jørgensen, H N, Rasmussen
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Nox/Duox family of nicotinamide adenine dinucleotide (phosphate) oxidases

Current Opinion in Hematology, 2002
Reactive oxygen species are classically described as occurring as an accidental byproduct of respiration, and are generally thought to be deleterious to biologic systems. The phagocyte nicotinamide adenine dinucleotide phosphate oxidase provides an example of deliberate reactive oxygen species generation, but the function of this enzyme is to ...
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