Effects of piperlonguminine on lung injury in severe acute pancreatitis via the TLR4/NF-κB pathway
Acute pancreatitis is an inflammatory response in the pancreas, involving activation of pancreatic enzymes. Severe acute pancreatitis (SAP) often causes systemic complications that affect distant organs, including the lungs. The aim of this study was to
Qian Hu+4 more
doaj +1 more source
The role of nicotinamide-β-adenine dinucleotide phosphate-H-cytochrome P450 oxidoreductase in the activation of cytochromes [PDF]
The aim of this theoretical study is to investigate the mechanisms of action of these enzymes in the context of metabolism in highly productive animals.
Popova Olga+3 more
doaj +1 more source
The limitations of the efficiency of ammonium-neutralizing erythrocyte-bioreactors based on glutamate dehydrogenase and alanine aminotransferase reactions were analyzed using a mathematical model.
Evgeniy Protasov+4 more
doaj +1 more source
Association of advanced glycation end products in Dupuytren disease
Background Advanced glycation end products are associated with aging, hyperglycemia, and oxidative stress. Accumulation of advanced glycation end products can cause various pathological conditions; however, the association of Dupuytren’s disease with ...
Fumiaki Takase+6 more
doaj +1 more source
It takes two to tango: NAD+ and sirtuins in aging/longevity control [PDF]
The coupling of nicotinamide adenine dinucleotide (NAD+) breakdown and protein deacylation is a unique feature of the family of proteins called ‘sirtuins.’ This intimate connection between NAD+ and sirtuins has an ancient origin and provides a ...
Guarente, Leonard, Imai, Shin-ichiro
core +2 more sources
Nicotinamide Adenine Dinucleotide and Nicotinamide Adenine Dinucleotide Phosphate-Linked Succinic Semialdehyde Dehydrogenases in a Pseudomonas Species [PDF]
A Pseudomonas species grown on polyamines was found to have the following enzymes that can dehydrogenate succinic semialdehyde: a constitutive nicotinamide adenine dinucleotide phosphate (NADP)-linked dehydrogenase, an inducible NAD-linked dehydrogenase specific for succinic semialdehyde (EC 1.2.lb), and more than ...
R. Padmanabhan, T. T. Tchen
openaire +3 more sources
Regulation of the Nicotinamide Adenine Dinucleotide- and Nicotinamide Adenine Dinucleotide Phosphate-Dependent Glutamate Dehydrogenases of Saccharomyces cerevisiae [PDF]
Saccharomyces cerevisiae contains two distinct l -glutamate dehydrogenases. These enzymes are affected in a reciprocal fashion by growth on ammonia or dicarboxylic amino acids as the nitrogen source. The specific activity of the nicotinamide adenine dinucleotide phosphate (NADP) (anabolic) enzyme is ...
Robert J. Roon, Harvey L. Even
openaire +3 more sources
Tissue-specific regulation of sirtuin and nicotinamide adenine dinucleotide biosynthetic pathways identified in C57Bl/6 mice in response to high-fat feeding [PDF]
Funding: The Scottish Government's Rural and Environment Science and Analytical Services Division.Peer ...
Drew, Janice E.+3 more
core +1 more source
The processes of the catalytic cycle of the cytochrome system associated with its activation by means of the enzyme Nicotinamide-β-adenine dinucleotide phosphate-H-ferrihemoprotein oxidoreductase [PDF]
The paper presents a theoretical study of the molecular mechanism of activation of the cytochrome P450 system by the enzyme Nicotinamide-β-adenine dinucleotide phosphate-H-ferrihemoprotein oxidoreductase in the catalytic cycle.
Popova Olga+3 more
doaj +1 more source
Oxidative stress in carotid arteries of patients submitted to carotid endarterectomy. The role of aging process [PDF]
PURPOSE: To evaluated the role of oxidative stress on aging process in patients submitted to carotid endarterectomy. METHODS: Twenty patients were divided into two groups: older group (≥ 70 years old); and the younger group (< 70 years old).
Márcio Luís Lucas+4 more
doaj +2 more sources