Results 51 to 60 of about 121,735 (279)

Nucleotides: Structure and Properties [PDF]

, 2005
Nucleotides consist of a nitrogen-containing base, a five-carbon sugar, and one or more phosphate groups. Cells contain many types of nucleotides, which play a central role in a wide variety of cellular processes, including metabolic regulation and the ...
Bowater, RP
core   +1 more source

Diphenyleneiodonium chloride synergizes with diazoxide to enhance protection against amyloid β induced neurotoxicity

Journal of Integrative Neuroscience, 2019
We examined synergistic effects of inhibiting reactive oxygen species generated from the mitochondria and from nicotinamide adenine dinucleotide phosphate oxidase on neurotoxicity. Primary hippocampal neurons were exposed to amyloid β, and the cells were
Qingxi Fu, Naiyong Gao, Fengyuan Che, Guangyin Xu, Hongxing Han, Quanping Su, Guozhao Ma   +6 more
doaj   +1 more source

Crossroads between peripheral atherosclerosis, western-type diet and skeletal muscle pathophysiology: emphasis on apolipoprotein E deficiency and peripheral arterial disease [PDF]

, 2017
Atherosclerosis is a chronic inflammatory process that, in the presence of hyperlipidaemia, promotes the formation of atheromatous plaques in large vessels of the cardiovascular system.
Matsakas, Antonios, Sfyri, Peggy
core   +1 more source

Nicotinamide Adenine Dinucleotide Phosphate Oxidase–Mediated Redox Signaling and Vascular Remodeling by 16α-Hydroxyestrone in Human Pulmonary Artery Cells

HYPERTENSION, 2016
Estrogen and oxidative stress have been implicated in pulmonary arterial hypertension (PAH). Mechanisms linking these systems are elusive. We hypothesized that estrogen metabolite, 16&agr;-hydroxyestrone (16&agr;OHE1), stimulates nicotinamide adenine ...
K. Hood, A. Montezano, Adam P. Harvey, M. Nilsen, M. MacLean, R. Touyz   +5 more
semanticscholar   +1 more source

Omega‐3 polyunsaturated fatty acids exert anti‐oxidant effects through the nuclear factor (erythroid‐derived 2)‐related factor 2 pathway in immortalized mouse Schwann cells

Journal of Diabetes Investigation, 2019
Aims/Introduction Recent studies advocate that omega‐3 polyunsaturated fatty acids (ω‐3 PUFAs) have direct anti‐oxidative and anti‐inflammatory effects in the vasculature; however, the role of ω‐3 PUFAs in Schwann cells remains undetermined.
Yasuaki Tatsumi, Ayako Kato, Kazunori Sango, Tatsuhito Himeno, Masaki Kondo, Yoshiro Kato, Hideki Kamiya, Jiro Nakamura, Koichi Kato   +8 more
doaj   +1 more source

High-Throughput Screening of a 2-Keto-L-Gulonic Acid-Producing Gluconobacter oxydans Strain Based on Related Dehydrogenases

Frontiers in Bioengineering and Biotechnology, 2019
High-throughput screening is a powerful tool for discovering strains in the natural environment that may be suitable for target production. Herein, a novel enzyme-based high-throughput screening method was developed for rapid screening of strains ...
Yue Chen, Yue Chen, Yue Chen, Li Liu, Li Liu, Li Liu, Xiaoyu Shan, Xiaoyu Shan, Xiaoyu Shan, Guocheng Du, Guocheng Du, Jingwen Zhou, Jingwen Zhou, Jingwen Zhou, Jian Chen, Jian Chen   +15 more
doaj   +1 more source

Single cell-based fluorescence lifetime imaging of intracellular oxygenation and metabolism

Redox Biology, 2020
Oxidation-reduction chemistry is fundamental to the metabolism of all living organisms, and hence quantifying the principal redox players is important for a comprehensive understanding of cell metabolism in normal and pathological states.
Rozhin Penjweini, Branden Roarke, Greg Alspaugh, Anahit Gevorgyan, Alessio Andreoni, Alessandra Pasut, Dan L. Sackett, Jay R. Knutson   +7 more
doaj   +1 more source

Evaluation of rate law approximations in bottom-up kinetic models of metabolism. [PDF]

, 2016
BackgroundThe mechanistic description of enzyme kinetics in a dynamic model of metabolism requires specifying the numerical values of a large number of kinetic parameters.
A Bordbar, A Dräger, A Flamholz, A Joshi, A Kinoshita, AB Canelas, Andreas Dräger, AR Tzafriri, BD Bennett, Bernhard O. Palsson, Bin Du, BO Palsson, BO Palsson, C Chassagnole, D Visser, D Visser, DA Fell, Daniel C. Zielinski, E Noor, Erol S. Kavvas, F Hadlich, Garri A. Arzumanyan, GE Briggs, J Almquist, J Schellenberger, JJ Heijnen, JR Karr, Justin Tan, K Smallbone, K Takahashi, Kayla E. Ruggiero, KR Sanft, LA Segel, LA Segel, M Bier, M Salter, M Scheer, N Jamshidi, N Jamshidi, N Jamshidi, N Zamboni, O Kotte, PJ Mulquiney, R Grima, S Schnell, SA Becker, U Alon, W Liebermeister, Y-Y Liu, Zhen Zhang   +49 more
core   +4 more sources

Non-labeling multiphoton excitation microscopy as a novel diagnostic tool for discriminating normal tissue and colorectal cancer lesions

Scientific Reports, 2017
Multiphoton excitation microscopy (MPM) is regarded as an effective tool that enables the visualization of deep regions within living tissues and organs, with little damage.
Takahiro Matsui, Hiroki Mizuno, Takao Sudo, Junichi Kikuta, Naotsugu Haraguchi, Jun-ichiro Ikeda, Tsunekazu Mizushima, Hirofumi Yamamoto, Eiichi Morii, Masaki Mori, Masaru Ishii   +10 more
doaj   +1 more source

Cloning, expression and characterization of alcohol dehydrogenases in the silkworm Bombyx mori

Genetics and Molecular Biology, 2011
Alcohol dehydrogenases (ADH) are a class of enzymes that catalyze the reversible oxidation of alcohols to corresponding aldehydes or ketones, by using either nicotinamide adenine dinucleotide (NAD) or nicotinamide adenine dinucleotide phosphate (NADP ...
Nan Wang, Haifeng Shi, Qin Yao, Yang Zhou, Lequn Kang, Huiqin Chen, Keping Chen   +6 more
doaj   +1 more source