Results 161 to 170 of about 51,366 (193)

Design of FK866-Based Degraders for Blocking the Nonenzymatic Functions of Nicotinamide Phosphoribosyltransferase.

Journal of Medicinal Chemistry
Nicotinamide phosphoribosyltransferase (NAMPT) is an attractive therapeutic target for treating select cancers. There are two forms of NAMPT: intracellular NAMPT (iNAMPT, the rate-limiting enzyme in the mammalian NAD+ main synthetic pathway) and ...
Tiangong Lu, Fangfang Chen, Jian Yao, Zixuan Bu, A. Kyani, Benji Liang, Shaoting Chen, Yuxiang Zheng, Hong Liang, Nouri Neamati, Yanghan Liu   +10 more
semanticscholar   +1 more source

Correction to: MicroRNA-26b Reduces Cell Viability by Inhibition of Nicotinamide Phosphoribosyltransferase in Breast Cancer Cells, by Melika Ameli Mojarad et al. DNA Cell Biol. 2022;41(8):735–741; doi: 10.1089/dna.2022.0214.

DNA and Cell Biology, 2022
Breast cancer (BC) is one of the most common causes of cancer in women worldwide and it is found to be associated with an increased level of Nicotinamide phosphoribosyltransferase (NAMPT), which plays an important role in nicotinamide adenine ...
Melika Ameli Mojarad, Mandana Ameli Mojarad, Alireza Pourmahdian   +2 more
semanticscholar   +1 more source

Discovery of a Potent Nicotinamide Phosphoribosyltransferase Activator for Improving Aging-associated Dysfunctions.

Journal of Medicinal Chemistry
Nicotinamide adenine dinucleotide (NAD+) plays a crucial role in the cellular energy metabolism pathway. Nicotinamide phosphoribosyltransferase (NAMPT) is a rate-limiting enzyme involved in the biosynthesis of NAD+.
Sicheng Yang, Donghuan Sun, Ying Wu, Shuqiang Chen, Yuan Guo, Jian Li, Guoqiang Dong, Chunquan Sheng   +7 more
semanticscholar   +1 more source

Recent advances of targeting nicotinamide phosphoribosyltransferase (NAMPT) for cancer drug discovery.

European journal of medicinal chemistry, 2023
He Tang, Lin Wang, Tianyu Wang, Jiamei Yang, Shuai Zheng, Jun Tong, Sheng Jiang, Xiangyu Zhang, Kuojun Zhang   +8 more
semanticscholar   +1 more source

Longitudinal Study of Plasma Visfatin/Nicotinamide Phosphoribosyltransferase (NAMPT) Levels in Healthy Pregnant Women

Reproductive Sciences, 2023
P. Nunes, R. Cavalli, V. Belo, V. Sandrim, M. Luizon   +4 more
semanticscholar   +1 more source

Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women

Science, 2021
Mihoko Yoshino, Jun Yoshino, Brandon D Kayser   +2 more
exaly  

Nicotinamide phosphoribosyltransferase in wound healing

American Journal of the Medical Sciences, 2023
A. Izadpanah, J. Rappaport
semanticscholar   +1 more source

Drug discovery targeting nicotinamide phosphoribosyltransferase (NAMPT): Updated progress and perspectives.

Bioorganic & Medicinal Chemistry
Fei Wen, Gang Gui, Xiaoyu Wang, Li Ye, Anqi Qin, Chen Zhou, Xiaoming Zha   +6 more
semanticscholar   +1 more source

Xanthones from Securidaca inappendiculata Hassk. attenuate collagen-induced arthritis in rats by inhibiting the nicotinamide phosphoribosyltransferase/glycolysis pathway and macrophage polarization.

International Immunopharmacology, 2022
Yuyan Zhou, Ruoxuan Xiang, G. Qin, Baozhen Ji, Shuo Yang, Guodong Wang, Jun Han   +6 more
semanticscholar   +1 more source

Extracellular nicotinamide phosphoribosyltransferase (eNAMPT) drives abnormal pericyte-rich vasculature in triple-negative breast cancer

Angiogenesis
M. Moro, Federica Carolina Balestrero, G. Colombo, S. Torretta, Nausicaa Clemente, Valerio Ciccone, E. Del Grosso, Sandra Donnini, C. Travelli, F. Condorelli, Sabina Sangaletti, Armando A Genazzani, A. A. Grolla   +12 more
semanticscholar   +1 more source