Results 171 to 180 of about 57,446 (263)

Data from Nicotinamide Phosphoribosyltransferase Acts as a Metabolic Gate for Mobilization of Myeloid-Derived Suppressor Cells

open access: gold, 2023
Cristina Travelli   +18 more
openalex   +1 more source

Harmonizing NAD+ metabolism with CeMOF nanozyme to orchestrate intraocular pressure modulation for glaucoma treatment

open access: yesView
Elevated intraocular pressure (IOP) is a critical risk factor for the development and progression of glaucoma. However, current treatments focus primarily on mechanical stress relief, neglecting the underlying issue of diminished cellular energy ...
Youjia Zhang   +10 more
doaj   +1 more source

Optimization of NAMPT (Nicotinamide Phosphoribosyltransferase) Activators: Discovery of N,N-Diethyl-1,2-benzoxazole-3-carboxamide Derivatives as Potent NAMPT Activators with Mitigated Mutagenic Risks

open access: diamond, 2021
Mayuko Akiu   +10 more
openalex   +1 more source

Mechanisms of the NAD+ salvage pathway in enhancing skeletal muscle function

open access: yesFrontiers in Cell and Developmental Biology
Nicotinamide adenine dinucleotide (NAD+) is crucial for cellular energy production, serving as a coenzyme in oxidation-reduction reactions. It also supports enzymes involved in processes such as DNA repair, aging, and immune responses.
Mengzhu Su   +7 more
doaj   +1 more source

The mechanism of nicotinamide phosphoribosyltransferase whereby positive allosteric modulation elevates cellular NAD + [PDF]

open access: gold, 2022
Kiira Ratia   +14 more
openalex   +1 more source

Nuclear Translocation of b-Catenin during Mesenchymal Stem Cells Differentiation into Hepatocytes Is Associated with a Tumoral Phenotype [PDF]

open access: yes, 2012
Wnt/b-catenin pathway controls biochemical processes related to cell differentiation. In committed cells the alteration of this pathway has been associated with tumors as hepatocellular carcinoma or hepatoblastoma.
Almadén Peña, Yolanda   +10 more
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