Results 301 to 310 of about 170,260 (319)
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Nicotine metabolism variability and nicotine addiction
Nicotine & Tobacco Research, 1999Individual variation in nicotine metabolism may play a role in a person's level of smoking, as well as in the transition from initiation to maintenance of a smoking behavior pattern. Since there is a paucity of research on nicotine metabolism in youth that smoke, a brief review of salient aspects of nicotine metabolism in adults provides a basis from ...
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Apoptosis, 2007
Cigarette smoking is associated with a plethora of different diseases. Nicotine is the addictive component of cigarette but also acts onto cells of the non-neuronal system, including immune effector cells. Although nicotine itself is usually not referred to as a carcinogen, there is ongoing debate whether nicotine functions as a 'tumor enhancer.' By ...
Kaj Albermann +2 more
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Cigarette smoking is associated with a plethora of different diseases. Nicotine is the addictive component of cigarette but also acts onto cells of the non-neuronal system, including immune effector cells. Although nicotine itself is usually not referred to as a carcinogen, there is ongoing debate whether nicotine functions as a 'tumor enhancer.' By ...
Kaj Albermann +2 more
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Nicotine and Nicotinic Receptor Involvement in Neuropsychiatric Disorders
Current Topics in Medicinal Chemistry, 2004Advances in the understanding of the neurobiology of the nicotinic receptor have started to be matched by an appreciation of the potential role of these receptors in a variety of neuropsychiatric disorders. While alterations in nicotinic receptor number and/or function have been associated with such conditions as Alzheimer's disease for several years ...
Alexandra Potter +2 more
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Nicotine and Nicotinic Receptors; Relevance to Parkinson’s Disease
NeuroToxicology, 2002The development of nicotinic agonists for therapy in neurodegenerative disorders such as Parkinson's disease is an area currently receiving considerable attention. The rationale for such work stems from findings that reveal a loss of nicotinic receptors in Parkinson's disease brains.
Maryka Quik, Jennifer M. Kulak
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1981
Cigarette smoking is one of the most persistent habits known to man; for many years, he has been possessed by the bizarre but irresistible urge to inhale the smoke produced by burning the dried and shredded leaves of Nicotiana tabacum. The alternative methods of administration, sniffing and chewing, lost favor with the introduction of cheap cigarettes ...
R. Kumar, M. Lader
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Cigarette smoking is one of the most persistent habits known to man; for many years, he has been possessed by the bizarre but irresistible urge to inhale the smoke produced by burning the dried and shredded leaves of Nicotiana tabacum. The alternative methods of administration, sniffing and chewing, lost favor with the introduction of cheap cigarettes ...
R. Kumar, M. Lader
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Nicotine, Brain Nicotinic Receptors, and Neuropsychiatric Disorders
Archives of Medical Research, 2000Neuronal nicotinic acetylcholine receptors (nAChRs) represent a large family of ligand-gated cation channels with diverse structures and properties. In contrast to the muscular nAChRs, the physiological functions of neuronal nAChRs are not well defined to date.
René Drucker-Colín, Stefan Mihailescu
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Treating Tobacco Addiction — Nicotine or No Nicotine?
New England Journal of Medicine, 1997Nicotine has been the mainstay of pharmacotherapy for tobacco addiction, but other medications, such as the antidepressant drugs bupropion and nortriptyline, are also effective.
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