Results 111 to 120 of about 1,153,102 (292)

The presence and stability of nicotine dependence symptoms among adolescents after the implementation of a smoking prevention program

open access: yes, 2019
Introduction Symptoms of nicotine dependence among adolescents occur at an early stage in smoking onset and can be present even with low exposure to cigarettes.
Monika Csibi   +4 more
core   +1 more source

A proteomic investigation of forebrain regeneration in the leopard gecko (Eublepharis macularius)

open access: yesDevelopmental Dynamics, EarlyView.
Our investigation reveals ontogenetic, injury‐ and regeneration‐associated proteomic changes in the leopard gecko forebrain. Abstract Background The ability to replace lost or damaged neurons following an injury is termed reactive neurogenesis. Although reactive neurogenesis has been reported in several lizard species, the molecular mechanisms ...
Alexandra I. Noble   +2 more
wiley   +1 more source

Characteristics of clients with nicotine dependence and short-term abstinence: findings from the USM Tobacco Quitline Service in Malaysia

open access: yes, 2018
Background Globally, quitlines have been shown to be an effective means for smoking cessation. The success of quitting among smokers is contributed by many factors such as nicotine dependence, motivation, income and educational levels, previous quit ...
Mohd Fadhli Razali   +7 more
core   +1 more source

Metabolic abnormalities and reprogramming in cats with naturally occurring hypertrophic cardiomyopathy

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1256-1270, April 2025.
Abstract Background and aims The heart is a metabolic organ rich in mitochondria. The failing heart reprograms to utilize different energy substrates, which increase its oxygen consumption. These adaptive changes contribute to increased oxidative stress.
Qinghong Li   +12 more
wiley   +1 more source

The Serendipitous Discovery of Rollover Cyclometalation: From Unrecognized Observation to Transformative Chemistry

open access: yesEuropean Journal of Inorganic Chemistry, EarlyView.
Rollover cyclometalation is a distinctive variant of classical cyclometalation where a chelated heterocyclic ligand undergoes internal rotation, releasing one donor atom from coordination and subsequently activating a remote C─H bond with high regioselectivity.
Antonio Zucca, Maria I. Pilo
wiley   +1 more source

Exploratory Evidence of a Gene–Smoking Interaction Involving MTR rs1805087 in Type 2 Diabetes Mellitus

open access: yesELECTROPHORESIS, EarlyView.
The graphical abstract illustrates how smoking interacts with an MTR rs1805087 gene variant to promote insulin resistance and β‐cell dysfunction through alterations in the folate cycle. PCR–RFLP genotyping and machine‐learning analysis support an exploratory assessment linking these combined factors to increased Type 2 diabetes risk in susceptible ...
João Pedro Costa Roriz   +5 more
wiley   +1 more source

Exposure to Secondhand Smoke and Nicotine Dependence [PDF]

open access: yes, 2005
Background Nicotine dependence (ND) : “the smoking behavior accompanied by a reluctance to quit (Khurana, Batra, Patkar, & Leone, 2003). The US Public Health Service Clinical Practice Guideline ‘Treating Tobacco Use and Dependence’: A chronic ...
Okoli, Chizimuzo T.C.   +3 more
core  

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

open access: yesEpilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang   +3 more
wiley   +1 more source

Body‐integrated photonic biosensors: Illuminating the path to active healthcare

open access: yesFlexMat, EarlyView.
Body‐integrated photonic biosensors are promising tools for active healthcare. These optical devices can be worn, implanted, or swallowed to monitor health signals continuously. This review introduces key sensing modalities, including fluorescence, colorimetry, SPR, LSPR, SERS, and light‐modulating materials.
Jiayue Gu   +10 more
wiley   +1 more source

Physicochemical, Functional, and Health‐Promoting Properties of Processed Nettle (Urtica Dioica) Leaves: A Review

open access: yesFuture Postharvest and Food, EarlyView.
Stinging nettle (Urtica dioica L.) leaves are a nutrient‐dense source of proteins, dietary fiber, chlorophylls, carotenoids, and phenolic compounds. Processing technologies enable the production of powders and extracts for incorporation into bakery, beverage, dairy, and nutraceutical products; however, challenges remain regarding sensory quality ...
Mary Nkongho Tanyitiku   +2 more
wiley   +1 more source

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