Results 101 to 110 of about 1,153,102 (292)

Lateral Habenula contribution in Nicotine addiction : focus on Dopamine, GABA and Serotonin Interactions [PDF]

, 2011
Compelling evidence has shown a pivotal role of dopaminergic function in drug addiction. Recently, the Habenula (Hb) has attracted a great deal of attention as another target for nicotine in the brain because of its role in regulating dopamine (DA ...
Zammit, Christian, Zammit C, Di Giovanni, Giuseppe, Muscat, Richard, Pitruzzella A, Muscat R, Pierucci M, Valentino, Mario, Benigno, Arcangelo, Di Giovanni G., Pierucci, Massimo, Valentino M, Pitruzzella, Alessandro   +12 more
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Population‐Stratified Distributions of Post‐Mortem Blood Drug Concentrations: An Epidemiological Framework for Contextual Interpretation

Drug Testing and Analysis, EarlyView.
Post‐mortem blood drug concentrations exhibit substantial overlap between deaths in which a drug was implicated and those in which it was not. Analysis of over 58,000 NPSUM cases demonstrates that demographic stratification does not resolve this uncertainty, reinforcing the need for contextual, evidence‐based interpretation rather than concentration ...
Thikra Algahtani, Kirsten L. Rock, Kathleen Rice‐Davies, Rebecca Lo, Benedict Morley, Stephen Morley, Caroline S. Copeland   +6 more
wiley   +1 more source

Nicotine dependence and readiness to quit tobacco among past and present alcohol abusers in Chennai, India - a comparative study

, 2018
Background Tobacco and alcohol are among the top causes of preventable deaths in the world, in most cases both these substances are used together. This study aims to compare the differences in nicotine dependence and the readiness to quit among past and ...
Arun Kumar Sundaragopal, Shyam Sivasamy, Preetha Elizabeth Chaly   +2 more
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Multiple Independent Loci at Chromosome 15q25.1 Affect Smoking Quantity [PDF]

, 2010
Recently, genetic association findings for nicotine dependence, smoking behavior, and smoking-related diseases converged to implicate the chromosome 15q25.1 region, which includes the CHRNA5-CHRNA3-CHRNB4 cholinergic nicotinic receptor subunit genes.
Kaprio J, Pillai S, Martin NG, Saccone NL, Leppert Mark F., Marissa A Ehringer, Wang, Jen C., Witt, Stephanie H., Jensen, Majken K., Sarah H. Stephens, Younghun Han, Peter Kraft, Amos Christopher I., Robert B Weiss, Culverhouse, Robert C., Broderick Peter, Stephanie H Witt, Bierut Laura J., Maria Teresa L, Culverhouse Robert C., Breslau Naomi, Markus M. Nöthen, Gapstur Susan M., Niu, Tianhua, Jen C Wang, Han, Younghun, Witt Stephanie H., Heliovaara, Markku, Thomas J Payne, Andrew C. Heath, Han, Shizhong, Landi MT, Kaprio, Jaakko, Yang BZ, Martin, Nicholas G., Gapstur, Susan M., Kendler KS, Wheeler William, Yufei Wang, Witt SH, Kendler Kenneth S., Wheeler, William, John P. Rice, Kaisu Keskitalo-Vuokko, Hunter David J., Margaret R Spitz, Sarah H Stephens, Ann Schwartz, Spitz, Margaret R., Nancy L. Saccone, Stephens SH, Ming D. Li, Wang JC, Dale S Cannon, Leena Peltonen, David J Hunter, Angela S. Wenzlaff, Andrew C Heath, Caporaso Neil E., Weiss Robert B., Hoft, Nicole R., Payne Thomas J., Neil E. Caporaso, Keskitalo-Vuokko, Kaisu, Landi, Maria Teresa, Breslau N, Sven Cichon, Xiangyang Kong, Breslau, Naomi, Hoft NR, Rietschel Marcella, Stevens VL, Noethen, Markus M., Nöthen, Markus M., Michele L Pergadia, Heliövaara M, Laura J Bierut, Chatterjee N, Michele L. Pergadia, Susan E Short, Robert C Culverhouse, Ina Giegling, Sun Lingwei, Chen X, Kaprio Jaakko, Jensen MK, Stephens Sarah H., Sherva R, Laura J. Bierut, Chen J, Li MD, Heath AC, Nicole R. Hoft, Majken K Jensen, Broderick P, Stevens Victoria L., Martin Nicholas G., Sherva, Richard, Marcella Rietschel, Aggen SH, Nancy L Saccone, Stephens, Sarah H., Peltonen, Leena, Sreekumar Pillai, Cannon Dale S., Sun, Lingwei, Eisen Tim, Mark F. Leppert, Angela S Wenzlaff, Giegling Ina, Bierut LJ, Heliovaara, Marku, Maria Teresa Landi, Pergadia Michele L., Markku Heliövaara, Hunter DJ, Stevens, Victoria L., Kenneth S Kendler, Keskitalo-Vuokko Kaisu, Cannon, Dale S., Ehringer, Marissa A., Schwantes-An Tae-Hwi, Landi, Maria T., Thomas J. Payne, Li Ming D., Peter Broderick, Montgomery GW, Cichon, Sven, Jingchun Chen, John P Rice, Han Younghun, Wang Jen C., Chen Jingchun, Aggen Steven H., Rujescu D, Nicholas G Martin, Rice John P., Pergadia, Michele L., Jennie Z Ma, Yang Bao-Zhu, Eisen T, Marissa A, Nilanjan Chatterjee, Hunter, David J., Madden Pamela A. F., Victoria L. Stevens, Neil E Caporaso, Sun, Juzhong, Steven H Aggen, Nicholas G. Martin, Kenneth S. Kendler, Chen, Xiangning, Cichon S, Landi Maria Teresa, Joel Gelernter, Mark F Leppert, William Wheeler, Gelemter, Joel, Heliövaara Markku, Kraft Peter, Susan E. Short, Saccone Nancy L., Gelernter Joel, Susan M. Gapstur, Chen, Jingchun, Cichon Sven, Wenzlaff AS, Tim Eisen, Heath Andrew C., Madden PA, Pillai, Sreekumar, Robert C. Culverhouse, Lingwei Sun, Chen Xiangning, Rice, John P., Bao-Zhu Yang, Chatterjee, Nilanjan, Richard Houlston, Kraft, Peter, Majken K. Jensen, Rice JP, Shizhong Han, Nicole R Hoft, Pergadia ML, Saccone, Nancy L., Ming D Li, Han Y, Sherva Richard, Montgomery Grant W., Han S, Culverhouse RC, Victoria L Stevens, Kong Xiangyang, Wheeler W, Pamela A F Madden, Dan Rujescu, Ma JZ, Gapstur SM, Steven H. Aggen, Christopher I. Amos, Wenzlaff Angela S., Schwartz Ann, Caporaso NE, Cannon DS, Hoft Nicole R., Short, Susan E., Tianhua Niu, Jen C. Wang, Eisen, Tim, Leppert MF, Wang Yufei, Niu Tianhua, Caporaso, Neil E., Heath, Andrew C., Kong, Xiangyang, Broderick, Peter, Schwartz, Ann, Juzhong Sun, Wenzlaff, Angela S., Weiss, Robert B., Bierut, Laura J., Peltonen L, Rujescu, Dan, Kong X, Yang, Bao-Zhu, Wang, Yufei, Christopher I Amos, Houlston R, Rujescu Dan, Weiss RB, Susan M Gapstur, Houlston Richard, Rietschel M, Schwantes-An, Tae-Hwi, Leppert, Mark F., Giegling, Ina, Richard Sherva, Montgomery, Grant W., Sun L, Amos CI, Gelernter J, Li, Ming D., Schwantes-An TH, Ehringer MA, Ma, Jennie Z., Sun Juzhong, Wang Y, Sun J, Kendler, Kenneth S., Xiangning Chen, Palotie, Leena, Payne TJ, Tae-Hwi Schwantes-An, Jaakko Kaprio, Nöthen Markus M., Naomi Breslau, Marissa A. Ehringer, Aggen, Steven H., Payne, Thomas J., Robert B, Kraft P, Grant W Montgomery, Margaret R. Spitz, Chatterjee Nilanjan, Spitz Margaret R., Houlston, Richard, Keskitalo-Vuokko K, Ma Jennie Z., David J. Hunter, Niu T, Stephanie H. Witt, Short Susan E., Rietschel, Marcella, Nöthen MM, Schwartz A, Grant W, Pillai Sreekumar, Markus M Nöthen, Pamela A. F. Madden, Han Shizhong, Amos, Christopher I., Giegling I, Dale S. Cannon, Grant W. Montgomery, Jensen Majken K., Spitz MR, Peltonen Leena, Gelernter, Joel, Jennie Z. Ma, Pamela A. F, Short SE, Robert B. Weiss, Madden, Pamela A. F., Ehringer Marissa A., Culverhouse, Robert C, Madden, Pamela A.F, Hunter, David, Jensen, Majken, Heath, Andrew C, Bierut, Laura J, Rice, John P, et al.,, Pergadia, Michele L, Short, Susan, Wang, Jen C, Saccone, Nancy L   +305 more
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Caps Off to Abstinence: Unraveling Synthetic Cannabinoid Contamination in Hair Analysis With Headgear Evidence?

Drug Testing and Analysis, EarlyView.
Scalp hair from a subject claiming 2‐year abstinence tested positive for MDMB‐4en‐PINACA and other synthetic cannabinoids. Analysis of the worn baseball cap revealed an identical drug profile, demonstrating external contamination – rather than active use – as the likely source and highlighting a critical pitfall in hair‐based abstinence testing ...
Annette Zschiesche, Yvonne S. Jungel, Detlef Thieme, Laura M. Huppertz, Merja A. Neukamm, Volker Auwärter   +5 more
wiley   +1 more source

Epidemiology, radiology, and genetics of nicotine dependence in COPD

Respiratory Research, 2011
Background Cigarette smoking is the principal environmental risk factor for developing COPD, and nicotine dependence strongly influences smoking behavior.
Hokanson John E, Washko George R, Hersh Craig P, Kim Deog Kyeom, Lynch David A, Newell John D, Murphy James R, Crapo James D, Silverman Edwin K   +8 more
doaj   +1 more source

Exploring the association between anhedonia and nicotine dependence: A study among female undergraduate students in Saudi Arabia

Introduction Nicotine dependence and its psychological foundations, including anhedonia, are major public health issues, especially among young adults.
Mai B. Alwesmi, Sana Hawamdeh, Fai A. Aseeri, Raghad A. Alqhatani, Sondus F. Alotaibi, Adam Saleh, May A. Alfohaid, Nourah A. Alghamdi, Jumanah K. Alghamdi, Futun M. Alharbi   +9 more
core   +1 more source

Fhod3 in zebrafish supports myofibril stability during growth of embryonic skeletal muscle

Developmental Dynamics, EarlyView.
Abstract Background Actin filament organization in cardiomyocytes critically depends on the formin Fhod3, but a role for Fhod3 in skeletal muscle development has not yet been described. Results We demonstrate here that in zebrafish mutated for one of two fhod3 paralog genes, fhod3a, skeletal muscle of the trunk appears normal through 2 days post ...
Aubrie Russell, Tracy Eng, Jeffrey D. Amack, David Pruyne   +3 more
wiley   +1 more source

Immediate early gene expression in the mesopontine tegmentum and midbrain after acute or chronic nicotine administration [PDF]

, 2008
The reinforcing properties of nicotine depend partly on cholinergic projections from the pedunculopontine tegmental (PPTg) and laterodorsal tegmental (LDTg) nuclei to midbrain dopamine neurons in the ventral tegmental area (VTA) and substantia nigra pars
Porter, Ailsa
core   +2 more sources

Links between intake of ethanol and nicotine and reward-related mechanisms [PDF]

, 1997
1. Examination was made of the effects of housing conditions on the preference of mice for dilute ethanol or water in a two-bottle choice. Isolating mice from groups of five after 10 days significantly increased their ethanol preference, compared to mice
Bermingham, Mara Roisin Laura
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