Results 81 to 90 of about 1,153,102 (292)

Association between self-esteem and nicotine dependence in adolescents

, 2017
SIGNIFICANCE: Early onset of nicotine dependence is associated with sustained and frequent smoking in adulthood and significant health consequences.
Lam, TH, CHEN, J, Ho, DSY, LEUNG, LT, Wang, MP   +4 more
core  

Differences in Cognitive Task Performance, Reinforcement Enhancement, and Nicotine Dependence Between Menthol and Nonmenthol Cigarette Smokers

, 2021
IntroductionMenthol has been shown to target similar brain regions and neural receptors as nicotine, yet the association between menthol cigarette use and cognitive performance remains unknown.Aims and methodsThis study examined differences in cognitive ...
Levin, Edward D, Jao, Nancy C, Hitsman, Brian, Simon, Melissa A, Melissa A Simon, Nancy C Jao, Brian Hitsman, Edward D Levin   +7 more
core   +1 more source

Histamine and the mechanisms of nausea and vomiting: Translating the uncertain pharmacology of cyclizine

British Journal of Clinical Pharmacology, EarlyView.
Abstract Cyclizine is a long‐established, short‐acting drug, registered for preventing motion sickness, post‐operative nausea and vomiting (PONV) and ‘vomiting of known cause’. The latter is not defined but may include pregnancy and patients receiving palliative care, historically accepted without large, controlled trials.
Gareth J. Sanger, Paul L. R. Andrews
wiley   +1 more source

The Brief Symptom Inventory-9 (BSI-9): Development and validation in a German general population sample

BMC Psychology
Background The Brief Symptom Inventory-18 (BSI-18) is a self-report questionnaire with three subscales, somatisation, anxiety, and depression, based on longer measures of distress.
C. MacDonald, K. Brophy, A. Coroiu, Elmar Braehler, A. Körner   +4 more
doaj   +1 more source

Nicotine dependence and psychological distress: outcomes and clinical implications in smoking cessation

, 2011
Fiammetta Cosci1, Francesco Pistelli2, Nicola Lazzarini1, Laura Carrozzi21Department of Psychology, University of Florence, Florence; 2University Unit of Pulmonology and Respiratory Pathophysiology, Cardiothoracic Department, University Hospital of Pisa,
Pistelli F, Lazzarini N, Carrozzi L, Cosci F   +3 more
core  

Pharmacokinetics and safety of a modified‐release psilocybin formulation: A SAD Phase I trial in normal‐weight and overweight/obese participants

British Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to evaluate the safety, tolerability and pharmacokinetics of a novel oral modified‐release psilocybin formulation (REL‐P11) in normal‐weight and overweight/obese healthy adults and to assess its suitability for controlled, subperceptual exposure, in light of emerging evidence supporting serotonergic modulation in metabolic ...
Anna Signor, Stefano Comai, Gianfranco Pasut, Franco Folli, Marco Gentilucci, Negar Gharavi, Sofia Raitsin, Thuy Van Nguyen, Marco Pappagallo, Andrea Mattarei, Paolo L. Manfredi, Sara De Martin   +11 more
wiley   +1 more source

Nicotine: evolution, dependence, and the path to total quit: redefining cessation in a changing nicotine landscape

Frontiers in Public Health
BackgroundThe nicotine marketplace has expanded beyond combustible cigarettes to include electronic nicotine delivery systems (ENDS), heated tobacco products (HTPs), nicotine pouches, and licensed medicinal nicotine products.
Maciej L. Goniewicz, Alex Bobak, Darush Attar-Zadeh, Matthias Raspe   +3 more
doaj   +1 more source

Rocavorexant, a novel, selective orexin‐1 receptor antagonist: Safety, tolerability and pharmacokinetics in healthy adults and individuals with opioid use disorder

British Journal of Clinical Pharmacology, EarlyView.
Aims Rocavorexant (INDV‐2000), a selective orexin‐1 receptor antagonist, reduces drug self‐administration and anxiety in nonclinical studies. This Phase 1 programme evaluated the safety, pharmacokinetics and pharmacodynamics of rocavorexant in healthy volunteers and treatment‐seeking individuals with opioid use disorder (OUD).
Martin Kankam, Rana Al‐Awam, Rajinder Shiwach, Andrew S. Huhn, Malcolm A. Young, Robert L. Dobbins   +5 more
wiley   +1 more source

Need for validation of fagerstrom test for nicotine dependence in Indian context: Implications for nicotine replacement therapy

Indian Journal of Psychological Medicine, 2016
Background: Variety of smokeable and chewable tobacco products with diverse nicotine content are used in India. Nicotine quantity in tobacco products has a direct bearing on developing tobacco dependence.
Manoj Kumar Sharma, Priyamvada Sharma
doaj   +1 more source

Immobilization of Alginate Microbeads With Whole‐Cells Expressing Nitrilase for Continuous Nicotinic Acid Production in Chip Millireactor

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The biocatalytic production of nicotinic acid using nitrilases has emerged as a promising alternative to conventional chemical synthesis, offering improved selectivity and environmental sustainability. In this study, we developed a continuous‐flow millireactor system employing Escherichia coli cells expressing a nitrilase from Paraburkholderia
Jonathan Bassut, Emina Mehić, Luana Cuvillier, Carine Vergne‐Vaxelaire, Jean‐Louis Petit, Maïté Michaud, Zoé Anxionnaz‐Minvielle, Anne Zaparucha, Guillaume Nonglaton   +8 more
wiley   +1 more source