Results 61 to 70 of about 40,499 (309)

Insights into the pathogenesis of nicotine addiction. Could a salivary biosensor be useful in Nicotine Replacement Therapy (NRT)? [PDF]

, 2019
Nicotine has gained the attention of the medical community due to its insidious addictive mechanisms which lead to chronic consumption. The multitude of compounds derived from tobacco smoke have local and systemic negative impacts, resulting in a large ...
Alexescu, Teodora G, Bordea, Roxana, Boșca, Bianca A, Băbțan, Anida-Maria, Câmpian, Radu S, Feurdean, Claudia N, Ilea, Aranka, Ionel, Anca, Miclăuș, Viorel, Mirică, Codruța I, Petrescu, Nausica B, Ruxanda, Flavia, Todea, Adina D, Uriciuc, Willi A   +13 more
core   +1 more source

Providing Nicotine Replacement Therapy in Focus Groups [PDF]

Nicotine & Tobacco Research, 2017
In many research studies, tobacco users are asked to forgo tobacco during study appointments to avoid interrupting study sessions with breaks or disrupting research flow and efficiency. Although onset of withdrawal varies according to levels of nicotine dependence, symptoms commonly begin within 30 minutes of abstinence.
Adam O. Goldstein, Ellen E. Jones, Kristen L. Jarman   +2 more
openaire   +3 more sources

Gut Metabolite Indole‐3‐Propionic Acid Regulates Macrophage Autophagy Through PPT1 Inhibiting Aging‐Related Myocardial Fibrosis

Advanced Science, EarlyView.
IPA is an intestinal tryptophan metabolite whose effects decline with decreased heart function. Supplementing IPA can alleviate the aging‐related myocardial fibrosis through PPT1. PPT1 is a key protein localized to lysosomes, and IPA can restore macrophage autophagy function by regulating PPT1 expresssions, thereby reducing aging‐related myocardial ...
Jing Lu, Hongyan Wang, Haiyu Zhang, Jiahao Li, Hanqi Li, Qiuyu Chen, Dongyu Han, Jialiang Liu, Lin Lv, Jie Xiong, Keying Yuan, Xianpeng Wei, Siqi Sheng, Fukai Liu, Yuanqi Shi, Zengxiang Dong, Yue Li   +16 more
wiley   +1 more source

Electronic cigarettes: health impact, nicotine replacement therapy, regulations

Pediatria i Medycyna Rodzinna, 2017
While the adverse effects of conventional cigarettes on human health have been thoroughly examined, in the last 15 years we have witnessed the birth of electronic cigarettes. There are many types of these devices available on the market.
Zygmunt Zdrojewicz, Damian Pypno, Bartosz Bugaj, Aleksandra Burzyńska   +3 more
doaj   +1 more source

Harmane Potentiates Nicotine Reinforcement Through MAO-A Inhibition at the Dose Related to Cigarette Smoking

Frontiers in Molecular Neuroscience, 2022
Nicotine is the primary addictive component in cigarette smoke, and dopamine release induced by nicotine is considered a significant cause of persistent smoking and nicotine dependence.
Zheng Ding, Zheng Ding, Zheng Ding, Xiangyu Li, Xiangyu Li, Xiangyu Li, Huan Chen, Huan Chen, Huan Chen, Hongwei Hou, Hongwei Hou, Hongwei Hou, Qingyuan Hu, Qingyuan Hu, Qingyuan Hu   +14 more
doaj   +1 more source

Cost-effectiveness of financial incentives for smoking cessation in pregnancy [PDF]

, 2016
No abstract ...
Bauld, Linda, Boyd, Kathleen, Tappin, David M.   +2 more
core   +1 more source

Weight Cycling Deregulates Eating Behavior in Mice via the Induction of Durable Gut Dysbiosis

Advanced Science, EarlyView.
Weight cycling in Humans is suspected to dysregulate eating behavior. Mice submitted to body weight cycling by alternating western‐type and regular chow diets display increased hedonic appetite when exposed to a palatable diet, reminiscent of binge‐eating episodes.
Mélanie Fouesnard, Adélie Salin, Sandy Ribes, Magali Monnoye, Gaëlle Champeil‐Potokar, Marie‐Sabelle Hjeij, Gwénaëlle Randuineau, Léa Le Gleau, Selma Ben Fradj, Catherine Philippe, Alexandre Benani, Isabelle Denis, Véronique Douard, Gaëlle Boudry   +13 more
wiley   +1 more source

The cost-effectiveness of smoking cessation support delivered by mobile phone text messaging: Txt2stop. [PDF]

, 2012
BACKGROUND: The txt2stop trial has shown that mobile-phone-based smoking cessation support doubles biochemically validated quitting at 6 months. This study examines the cost-effectiveness of smoking cessation support delivered by mobile phone text ...
Cairns, John, Free, Caroline, Guerriero, Carla, Roberts, Ian, Rodgers, Anthony, Whittaker, Robyn   +5 more
core   +2 more sources

Multi‐Omics and ‐Organ Insights into Energy Metabolic Adaptations in Early Sepsis Onset

Advanced Science, EarlyView.
This study shows that patients at risk of sepsis have a distinct metabolite and lipid signature, including serine and aminoadipic acid, in their serum before clinical diagnosis. A mouse model of sepsis with a compatible serum signature reveals underlying metabolic changes, including mitochondrial adaptation, altered serine‐dependent purine metabolism ...
Lin‐Lin Xu, Zhengyuan Zhou, Sascha Schäuble, Wolfgang Vivas, Karen Dlubatz, Michael Bauer, Sebastian Weis, Mervyn Singer, Roman Lukaszewski, Gianni Panagiotou   +9 more
wiley   +1 more source

Pharmacological Basis of the Clinical Efficacy of Varenicline Used to Facilitate Smoking Cessation

Рациональная фармакотерапия в кардиологии, 2019
Modern problems caused by the high prevalence of smoking, as well as pharmacological approaches that facilitate quitting smoking are discussed in the review.
S. R. Gilyarevskiy
doaj   +1 more source