Results 61 to 70 of about 43,310 (310)

ANTI-NICOTINE VACCINES: NEW PERSPECTIVE FOR SMOKERS AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD)

open access: yesBerkala Kedokteran, 2017
: Smoking and Chronic Obstructive Pulmonary Disease (COPD) become a global problem in the world. The increasing number of smokers in the world also led to significantly increased morbidity and mortality due to COPD.
Marsheilla Riska
doaj   +1 more source

Astrocytic PCBP1 Suppresses Ferroptosis to Restore Glutamatergic Homeostasis and Mitigate Stress‐Induced Depression in Male Mice

open access: yesAdvanced Science, EarlyView.
This study demonstrates that polyC‐RNA‐binding protein 1 (PCBP1) in ventral hippocampal astrocytes modulates depressive‐like behaviors by regulating glutathione peroxidase 4‐mediated ferroptosis and synaptic glutamatergic transmission. PCBP1 overexpression intervention in the chronic unpredictable mild stress model rescues behavioral deficits ...
Jinyu Zhang   +15 more
wiley   +1 more source

Supra and subgingival application of antiseptics or antibiotics during periodontal therapy

open access: yesPeriodontology 2000, EarlyView., 2023
Abstract Periodontal diseases (gingivitis and periodontitis) are characterized by inflammatory processes which arise as a result of disruption of the balance in the oral ecosystem. According to the current S3 level clinical practice guidelines, therapy of patients with periodontitis involves a stepwise approach that includes the control of the patient ...
Elena Figuero   +5 more
wiley   +1 more source

Reality Versus Grant Application Research “Plans” [PDF]

open access: yes, 2018
This article describes the implementation of the American Indian mHealth Smoking Dependence Study focusing on the differences between what was written in the grant application compared to what happened in reality.
Addo, Ivor D.   +13 more
core   +1 more source

3D Hydrogel Cell Cultures and Their Biomedical Applications

open access: yesAdvanced NanoBiomed Research, EarlyView.
The review highlights the advantages of hydrogel‐based 3D cell cultures over traditional 2D models. These hydrogels closely mimic natural cellular environments, improving research in tissue engineering, drug discovery, cancer studies, and neuroscience.
Tri Lan Thai   +7 more
wiley   +1 more source

Efficacy of standard nicotine replacement therapy (NRT) versus video-assisted nurse-led NRT on tobacco cessation: A randomized controlled pilot trial

open access: yesClinical Epidemiology and Global Health, 2021
Introduction: Nicotine effectiveness has been tested in multiple forms to stop tobacco use. However, the evidence remains inconclusive for the efficacy of a single nicotine intervention.
Hoineiting Rebecca Haokip   +3 more
doaj   +1 more source

Nicotine replacement therapy for smoking cessation

open access: yesCochrane Database of Systematic Reviews, 2012
The aim of nicotine replacement therapy (NRT) is to temporarily replace much of the nicotine from cigarettes to reduce motivation to smoke and nicotine withdrawal symptoms, thus easing the transition from cigarette smoking to complete abstinence.The aims of this review were: To determine the effect of NRT compared to placebo in aiding smoking cessation,
Stead, L   +6 more
openaire   +3 more sources

Drug‐Induced Raynaud's Phenomenon and Underlying Mechanism: A Disproportionality Analysis From the World Health Organization Pharmacovigilance Database

open access: yesArthritis &Rheumatology, EarlyView.
Objectives The aim of this study is to generate hypotheses about unknown drugs associated with the onset or worsening of Raynaud's phenomenon (RP) and to explore their potential pathophysiologic mechanisms through a mixed disproportionality/clustering analysis from the World Health Organization (WHO) pharmacovigilance database.
Alex Hlavaty   +4 more
wiley   +1 more source

New Biomarkers Based on Smoking-Related Phenotypes for Smoking Cessation Outcomes of Nicotine Replacement Therapy: A Prospective Study [PDF]

open access: diamond, 2021
Arash Nikkholgh   +5 more
openalex   +1 more source

Low‐dose cannabidiol increases plasma concentrations of amitriptyline: A clinical drug–drug interaction study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Cannabidiol (CBD), the main non‐intoxicating compound from the cannabis plant, is regularly used by patients with chronic pain who also take analgesics. CBD has previously been shown to inhibit CYP‐mediated drug metabolism. This study aimed to characterize the potential pharmacokinetic interaction of CBD with amitriptyline and tramadol ...
Andriy A. Gorbenko   +9 more
wiley   +1 more source

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