Results 61 to 70 of about 3,355,558 (275)

The impact of pharmacogenetic‐informed care on medication adherence and psychological factors associated with adherence: A narrative review

British Journal of Clinical Pharmacology, EarlyView.
Improvement in medication adherence is often proposed as a potential advantage of pharmacogenetic‐guided prescribing over a traditional one‐size‐fits‐all approach. This paper provides a review of the published literature and presents the findings of studies that measure adherence to medication as an outcome of pharmacogenetic‐informed care, or that ...
Lucy Galloway, Alison Wright, John Weinman   +2 more
wiley   +1 more source

Efficacy of standard nicotine replacement therapy (NRT) versus video-assisted nurse-led NRT on tobacco cessation: A randomized controlled pilot trial

Clinical Epidemiology and Global Health, 2021
Introduction: Nicotine effectiveness has been tested in multiple forms to stop tobacco use. However, the evidence remains inconclusive for the efficacy of a single nicotine intervention.
Hoineiting Rebecca Haokip, Dr Rajesh Kumar, Dr Vikram Singh Rawat, Dr Suresh Kumar Sharma   +3 more
doaj   +1 more source

Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges

BMEMat, EarlyView.
This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma, Nan Jiang, Liyuan Chen, He Zhang, Xinjia Cai, Karan Gulati, Danqing He, Zhigang Cai, Yan Liu   +8 more
wiley   +1 more source

A review of the inhibitory waste metabolites produced during mAb biomanufacturing

Biotechnology Progress, EarlyView.
The review highlights inhibitory metabolites in CHO cell cultures, such as lactate, ammonia, isobutyrate, and isovalerate, impacting growth and productivity. Identification methods include LC/MS‐based metabolomics, while control strategies involve media optimization, genetic engineering, and process adjustments (pH, temperature).
Zhao Wang, Caitlin Morris, Duc Hoang, Jianlin Xu, Michael C. Borys, Seongkyu Yoon   +5 more
wiley   +1 more source

Nicotine replacement therapy for smoking cessation

Cochrane Database of Systematic Reviews, 2012
The aim of nicotine replacement therapy (NRT) is to temporarily replace much of the nicotine from cigarettes to reduce motivation to smoke and nicotine withdrawal symptoms, thus easing the transition from cigarette smoking to complete abstinence.The aims of this review were: To determine the effect of NRT compared to placebo in aiding smoking cessation,
Stead, L, Perera, R, Bullen, C, Mant, D, Hartmann-Boyce, J, Cahill, K, Lancaster, T   +6 more
openaire   +3 more sources

Initiation of Gabapentin with Opioids and Risk of Respiratory Cardiovascular and Opioid‐Related Adverse Events Following Surgery for Breast Cancer

Clinical Pharmacology &Therapeutics, EarlyView.
Pain is a key determinant of quality‐of‐life following breast cancer surgery, the most common cancer operation in the United States. Gabapentinoids are frequently prescribed for pain management, yet their respiratory, cardiovascular, and opioid‐related adverse effects remain unclear.
Jyun‐Heng Lai, Anton L V Avanceña, Juan P Cata, Jamie C. Barner, Sharon H. Giordano, Chanhyun Park, Hui Zhao, Kirk E. Evoy, John K. Lin, Jennifer C. Spencer, Mariana Chavez‐MacGregor, Kelly K. Hunt, Kerollos Nashat Wanis   +12 more
wiley   +1 more source

Design and Preclinical Evaluation of Nicotine–Stearic Acid Conjugate-Loaded Solid Lipid Nanoparticles for Transdermal Delivery: A Technical Note

Pharmaceutics, 2023
This study aimed to develop and evaluate nicotine--stearic acid conjugate-loaded solid lipid nanoparticles (NSA-SLNs) for transdermal delivery in nicotine replacement therapy (NRT).
Jwala Renukuntla, Samuel Peterson-Sockwell, Bradley A. Clark, Nipunika H. Godage, Emanuela Gionfriddo, Pradeep Kumar Bolla, Sai H. S. Boddu   +6 more
doaj   +1 more source

Nicotine Replacement Therapy as a Maintenance Treatment [PDF]

JAMA, 2015
IMPORTANCE The US Food and Drug Administration adopted labeling for nicotine patches to allow use beyond the standard 8 weeks. This decision was based in part on data showing increased efficacy for 24 weeks of treatment. Few studies have examined whether the use of nicotine patches beyond 24 weeks provides additional therapeutic benefit.
openaire   +4 more sources

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source

Conceptual obstacles to making use of four smoking-cessation strategies: What reasons do light smokers give for rejecting strategies?

Health Psychology Open, 2015
Some smokers have safety and cost concerns about nicotine replacement therapy which discourage its use. We recruited 56 young adult light smokers to read detailed descriptions of a hybrid nicotine replacement therapy, a prescription drug treatment ...
Michael P Ryan, Jennifer J Hinojosa
doaj   +1 more source