Results 81 to 90 of about 43,310 (310)

GP prescribing of nicotine replacement and bupropion to aid smoking cessation in England and Wales [PDF]

, 2004
Aims Prescribing nicotine replacement therapy (NRT) or bupropion for smoking cessation is of considerable importance to public health but little is known about prescribing practices.
McEwen, A, Owen, L, West, R
core   +1 more source

Continuous outcome estimation in N‐of‐1 trials for accelerated decision‐making

Epilepsia, EarlyView.
Abstract Objective N‐of‐1 trials aim to determine the therapeutic effect for a single individual. This individualized approach necessitates collecting multiple data points over time through repeated alternating periods of active treatment and a comparator or control condition.
Victoria Defelippe, František Bartoš, Eric‐Jan Wagenmakers, Kees P. J. Braun, Floor E. Jansen, Willem M. Otte   +5 more
wiley   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source

Is a combination of varenicline and nicotine patch more effective in helping smokers quit than varenicline alone? A randomised controlled trial [PDF]

, 2013
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work ...
A McEwen, AC Farley, Al-Rehan Dhanji, D Gonzales, DE Jorenby, H McRobbie, Hayden McRobbie, HJ Aubin, JA Stapleton, JJ Prochaska, JO Ebbert, K Cahill, Katie Myers Smith, L Bauld, LF Stead, MC Fiore, N Lindson, P Hajek, P Hajek, Peter Hajek, R West, R West, R West, S Shiffman, S Shiffman, T Health, TF Heatherton   +26 more
core   +2 more sources

Molecular imprinting for neurology: Materials, applications, and limitations

Ibrain, EarlyView.
Molecularly imprinted materials: diagnostic, therapeutic and research applications in neurology. Molecularly imprinted materials offer high specificity and affinity for target molecules in neurological applications. This review highlights their synthesis, characterisation, and use in diagnostics, research and therapeutics.
Xiaohan Ma, Yingqi Ma, Claudia Marino, Alessandro Poma   +3 more
wiley   +1 more source

The barriers to smoking cessation in Swiss methadone and buprenorphine-maintained patients

Harm Reduction Journal, 2008
Background Smoking rates in methadone-maintained patients are almost three times higher than in the general population and remain elevated and stable.
Stohler Rudolf, Boesch Lukas, Klaeusler Beat, Schaub Michael, Wapf Victoria, Eich Dominique   +5 more
doaj   +1 more source

Comparison of Allen Carr's Easyway programme with a specialist behavioural and pharmacological smoking cessation support service: a randomized controlled trial. [PDF]

, 2020
BACKGROUND AND AIMS: A combination of behavioural and pharmacological support is judged to be the optimal approach for assisting smoking cessation. Allen Carr's Easyway (ACE) is a single-session pharmacotherapy-free programme that has been in operation ...
Albery, I., Albery, I., Brunger, H., Brunger, H., Burghelea, M., Burghelea, M., Frings, D., Frings, D., Moss, A., Moss, A., White, S., White, S., Wood, K., Wood, K.   +13 more
core   +2 more sources

Investigation of the Mechanism of Cinnamaldehyde in Irritable Bowel Syndrome Based via Network Pharmacology, Molecular Docking, and Animal Experiments

Pediatric Discovery, EarlyView.
Through network pharmacology and molecular docking, it has been discovered that CA can target MAOB, among other proteins, to exert a therapeutic effect in IBS. In vivo, CA lowered visceral hypersensitivity, anxiety and depression‐like behaviors, and fecal water content, highlighting its therapeutic potential for IBS via anti‐inflammatory pathways ...
Qingyang Yu, Boqing Xu, Chunfang Dai, Yayan Pang, Zhifang Dong   +4 more
wiley   +1 more source

Qualitative study of pilot payment aimed at increasing general practitioners' antismoking advice to smokers [PDF]

, 2001
OBJECTIVES: To elicit general practitioners' and practice nurses' accounts of changes in their clinical practice or practice organisation made to claim a pilot health promotion payment.
Cheater, F., Coleman, T., Stevenson, K., Wynn, A.T.   +3 more
core   +2 more sources

From Tobacco to Ultraprocessed Food: How Industry Engineering Fuels the Epidemic of Preventable Disease

The Milbank Quarterly, EarlyView.
Policy Points Ultraprocessed foods (UPFs) are engineered to heighten reward and accelerate delivery of reinforcing ingredients, driving compulsive consumption and disrupting appetite regulation. This is a growing challenge for health policy. UPFs share key engineering strategies adopted from the tobacco industry, such as dose optimization and hedonic ...
ASHLEY N. GEARHARDT, KELLY D. BROWNELL, ALLAN M. BRANDT   +2 more
wiley   +1 more source