Pharmacokinetic differences in nicotine and nicotine salts mediate reinforcement-related behavior: an animal model study [PDF]
Frontiers in Neuroscience, 2023 Since their introduction in the United States and Europe in 2007, electronic cigarettes (E-Cigs) have become increasingly popular among smokers. Nicotine, a key component in both tobacco and e-cigarettes, can exist in two forms: nicotine-freebase (FBN ...
Pengfei Han +36 more
doaj +4 more sources
Pharmacological effects of nicotine salts on dopamine release in the nucleus accumbens [PDF]
Frontiers in Pharmacology, 2023 With the growing number of individuals regularly using e-cigarettes, it has become increasingly important to understand the psychobiological effects of nicotine salts.
Xiaonan Li +9 more
doaj +4 more sources
In vitro toxicological evaluation of aerosols generated by a 4th generation vaping device using nicotine salts in an air-liquid interface system [PDF]
Respiratory ResearchBackground Electronic cigarettes (EC) have gained popularity, especially among young people, with the introduction of fourth-generation devices based on e-liquids containing nicotine salts that promise a smoother vaping experience than freebase nicotine.
Clément Mercier +3 more
doaj +4 more sources
Crystal structures and hydrogen bonding in the proton-transfer salts of nicotine with 3,5-dinitrosalicylic acid and 5-sulfosalicylic acid [PDF]
Acta Crystallographica Section E, 2014 The structures of the 1:1 anhydrous salts of nicotine (NIC) with 3,5-dinitrosalicylic acid (DNSA) and 5-sulfosalicylic acid (5-SSA), namely (1R,2S)-1-methyl-2-(pyridin-3-yl)-1H-pyrrolidin-1-ium 2-carboxy-4,6-dinitrophenolate, C10H15N2+·C7H3N2O7−, (I ...
Graham Smith, Urs D. Wermuth
doaj +4 more sources
Frontiers in Environmental Science, 2023 Volatile organic chemicals (VOCs) released from e-cigarettes are a special source of air pollutants. In this work, we investigated the VOCs released from six nicotine salts (namely, nicotine benzoate, nicotine tartrate, nicotine citrate, nicotine malate,
Ji Yang +6 more
doaj +2 more sources
Inhibition of nicotine-induced Streptococcus mutans biofilm formation by salts solutions intended for mouthrinses [PDF]
Restorative Dentistry & Endodontics, 2019 ObjectivesBiofilm formation is critical to dental caries initiation and development. The aim of this study was to investigate the effects of nicotine exposure on Streptococcus mutans (S. mutans) biofilm formation concomitantly with the inhibitory effects
Abdulrahman A. Balhaddad +2 more
doaj +3 more sources
Vaping cessation: how to treat nicotine dependence and tailor the nicotine replacement dose. A narrative review [PDF]
Jornal Brasileiro de PneumologiaElectronic nicotine delivery systems, electronic cigarettes, or vapes have been extensively marketed as a safer alternative to combustible cigarettes and as aids for smoking cessation.
Stella Regina Martins +5 more
doaj +2 more sources
Lactic Acid Salts of Nicotine Potentiate the Transfer of Toxic Metals into Electronic Cigarette Aerosols [PDF]
ToxicsThe designs and liquid formulations of Electronic Nicotine Delivery System (ENDS) devices continue to rapidly evolve. Thus, it is important to monitor and characterize ENDS aerosols for changes in toxic constituents.
R. Steven Pappas +3 more
doaj +2 more sources
Characterization of Nicotine Salts in 23 Electronic Cigarette Refill Liquids. [PDF]
Nicotine Tob Res, 2020 Harvanko AM +3 more
europepmc +3 more sources
Efficient Method of (S)-Nicotine Synthesis [PDF]
MoleculesImproved methods for the synthesis of nicotine are of great importance due to the wide range of applications of synthetic nicotine, which is free from contamination with nitrosamines.
Nazar Trotsko +5 more
doaj +2 more sources