Results 101 to 110 of about 75,040 (266)

Nicotine as Therapy

open access: yesPLoS Biology, 2004
In daily use for centuries by hundreds of millions of people, nicotine has only lately been investigated for its therapeutic potential in a long list of common ...
openaire   +4 more sources

Body‐integrated photonic biosensors: Illuminating the path to active healthcare

open access: yesFlexMat, EarlyView.
Body‐integrated photonic biosensors are promising tools for active healthcare. These optical devices can be worn, implanted, or swallowed to monitor health signals continuously. This review introduces key sensing modalities, including fluorescence, colorimetry, SPR, LSPR, SERS, and light‐modulating materials.
Jiayue Gu   +10 more
wiley   +1 more source

Beyond Gut Modulation: A Critical Review of the Therapeutic Potential, Safety, and Clinical Prospects of Natural Polysaccharides for IBD

open access: yesFood Safety and Health, EarlyView.
In this review, we critically summarized the application of natural polysaccharides (NPs) for the treatment of IBD. This approach combines, in a unique way (right), the basic structure–activity relationships of NPs from different origins (left) with their multipronged mode of action, which involves modulation of the gut microbiota and other ...
Felix Danso   +3 more
wiley   +1 more source

Beyond Tobacco Prevention: The Effects of Tobacco 21 Laws on Young Adults' Body Weight

open access: yesHealth Economics, EarlyView.
ABSTRACT Tobacco 21 (T21) laws effectively reduce youth tobacco use by preventing initiation. This study examines their impact on body weight among young adults aged 18–20. Using 2009–2019 Behavioral Risk Factor Surveillance System data and a two‐way fixed‐effects difference‐in‐differences (DID) design, we find limited evidence of broad weight changes ...
Qihua Qiu, Jaesang Sung
wiley   +1 more source

Cigarette Smoke Exposure Attenuates T2R‐Mediated Apoptosis in Head and Neck Squamous Cell Carcinoma

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Tobacco use is associated with worse outcomes in head and neck squamous cell carcinoma (HNSCC). Bitter taste receptor (T2R) activation induces apoptosis via calcium‐dependent signaling, and higher T2R expression correlates with increased survival in HNSCC.
Kyle Polen   +10 more
wiley   +1 more source

Advances and Challenges in Functional Abrasive Design for Chemical Mechanical Polishing of Semiconductors and in Optical Manufacturing

open access: yesInterdisciplinary Materials, EarlyView.
This review summarizes recent advances in chemical mechanical polishing abrasives based on CeO2, SiO2, Al2O3, and emerging nanomaterials, highlighting how structural engineering and interfacial chemistry govern material removal and surface quality. Mechanism‐driven abrasive design is identified as a key pathway toward high selectivity, low damage, and ...
Wenqi Tang   +11 more
wiley   +1 more source

Chemotherapy‐Induced Nausea and Vomiting in Early Breast Cancer Patients Receiving Adjuvant Chemotherapy With Fluorouracil, Epirubicin, Cyclophosphamide Followed by Docetaxel Versus an Anthracycline‐Free Regimen With Docetaxel, Cyclophosphamide—Results From a Randomized Clinical Trial

open access: yesInternational Journal of Cancer, EarlyView.
Chemotherapy‐induced nausea and vomiting (CINV) remains a significant clinical problem despite modern antiemetics. In particular, antiemetic strategies for emerging cancer therapies lack detailed evaluation. This randomized trial analyzed hourly CINV data for patients with early breast cancer who received either docetaxel plus cyclophosphamide (TC) or ...
Manuel Hörner   +16 more
wiley   +1 more source

Engineered 3D cultured human nasal mucosa mesenchymal stem cell derived sEVs for targeted brain‐derived neurotrophic factor delivery to enhance neurogenesis and attenuate brain damage

open access: yesInterdisciplinary Medicine, EarlyView.
This study successfully developed and evaluated BDNF@RVG‐sEVs, a novel brain‐targeted nanomedicine based on hnmMSC‐derived sEVs, designed to overcome the BBB and enhance neurorestoration. By integrating RVG for enhanced brain targeting and encapsulating BDNF for potent neurorepair, our system address the key limitations of the conventional sEVs and ...
Xueting Wang   +13 more
wiley   +1 more source

Adverse Childhood Experiences and Substance Use: The Mediating Role of Executive Function Deficits

open access: yesJournal of Adolescence, EarlyView.
ABSTRACT Introduction While adverse childhood experiences (ACEs) are robust risk factors for adolescent substance use, the prospective neurocognitive pathways linking both cumulative and specific adversities to substance use remain understudied. This study tested a vulnerability model by examining whether executive function (EF) deficits mediate the ...
Mahsa P. Yousefkhani   +2 more
wiley   +1 more source

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