Methods to Produce Nicotinic Acid with Potential Industrial Applications [PDF]
Materials, 2022 Nicotinic acid is a naturally occurring pyridine carboxylic acid, contained in vitamin PP, an essential nutrient for humans and animals, and used as an antipelagic agent. Nicotinic acid can be made from tryptophan by plants and animals but is usually not
Dawid Lisicki, Beata Orlinska
exaly +3 more sources
Enzymatic approaches to nicotinic acid synthesis: recent advances and future prospects [PDF]
Frontiers in Bioengineering and BiotechnologyBiocatalyst-mediated reactions have led to revolutionary transformations in the organic synthesis of pharmaceuticals, drugs, and other chemicals.
Rahul Vikram Singh +5 more
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Nicotinic acid: a lipid-lowering agent with unrealized potential
The Egyptian Journal of Internal Medicine, 2014 Nicotinic acid is a well-known treatment for dyslipidemia in adults. This review article explored not only the role of nicotinic acid in dyslipidemia but also its role in hypertension and as a cardioprotective agent.
Samar H. Aboulsoud
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In silico prediction of some pharmacokinetic, safety, biological activity and molecular docking studies of 1-piperazine indole hybrid with nicotinic amide and nicotinic acid and their analogues [PDF]
SAGE Open MedicineBackground: In silico predictions are now being utilized in drug discovery and design to assess the physicochemical, pharmacokinetics, and safety properties of compounds at the beginning of the drug discovery process.
Melese Legesse Mitku +7 more
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مجله دانشکده پزشکی اصفهان, 2021 Background: Reactive oxygen species (ROS) are of the most important detrimental factors on sperm quality during freezing process, which increases the lipid peroxidation (LPO) of cell membranes.
Zahra Sadeghi +2 more
doaj +1 more source
Solution thermodynamics of aqueous nicotinic acid solutions in presence of tetrabutylammonium hydrogen sulphate [PDF]
Journal of the Serbian Chemical Society, 2013 In this study we investigated the effects of tetrabutylammonium hydrogen sulphate (Bu4NHSO4) on the solute-solute and solute-solvent interactions in the aqueous solutions of nicotinic acid in terms of apparent molar volumes (φV), standard partial ...
Sarkar Abhijit, Sinha Biswajit
doaj +1 more source
Journal of Animal Science and Technology, 2019 Vitamin B3 (niacin) is essential for all living cells and plays a central role in energy metabolism and oxidative phosphorylation. Vitamin B3, a water-soluble vitamin, is present in the form of nicotinic
Jale Çatak
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Biomolecules, 2015 Alcohol consumption causes nicotinic acid deficiency. The present study was undertaken to determine whether dietary nicotinic acid supplementation provides beneficial effects on alcohol-induced endotoxin signaling and the possible mechanisms at the gut ...
Wei Zhong +5 more
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Nrt1 and Tna1-independent export of NAD+ precursor vitamins promotes NAD+ homeostasis and allows engineering of vitamin production. [PDF]
PLoS ONE, 2011 NAD(+) is both a co-enzyme for hydride transfer enzymes and a substrate of sirtuins and other NAD(+) consuming enzymes. NAD(+) biosynthesis is required for two different regimens that extend lifespan in yeast.
Peter Belenky +4 more
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Lack of nicotinic acid effect on cholesterol metabolism of the rat*
Journal of Lipid Research, 1960 The effect of the addition of 1 per cent nicotinic acid to the diet of the rat on serum, liver, and carcass cholesterol, and on the incorporation of acetate-1-C14 into cholesterol by the intact animal were studied.
Charles H. Duncan, Maurice M. Best
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