Enzymatic approaches to nicotinic acid synthesis: recent advances and future prospects [PDF]
Frontiers in Bioengineering and BiotechnologyBiocatalyst-mediated reactions have led to revolutionary transformations in the organic synthesis of pharmaceuticals, drugs, and other chemicals.
Rahul Vikram Singh +5 more
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Scientific Opinion on the safety and efficacy of niacin (nicotinic acid and nicotinamide) as a feed additive for all animal species based on a dossier submitted by Lonza Benelux BV [PDF]
EFSA Journal, 2012 <p>The term ‘niacin’ is used as a generic description of nicotinic acid and nicotinamide with pyridine as the basic structure. Nicotinic acid and nicotinamide function mainly as precursors of the co-enzymes NAD and NADP.
EFSA Panel on Additives and Products or Substances used in Animal Feed
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A New Method for the Determination of Nucleic Acid Using an Eu3+– nicotinic Acid Complex as a Resonance Light Scattering Probe [PDF]
Molecules, 2008 This study found that in Tris-HCl buffer, the resonance light scattering (RLS) intensity of the Eu3+-nicotinic acid system can be greatly enhanced by nucleic acids and the enhanced intensity is proportional to the concentration of nucleic acid in the ...
Jing-He Yang +4 more
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In silico prediction of some pharmacokinetic, safety, biological activity and molecular docking studies of 1-piperazine indole hybrid with nicotinic amide and nicotinic acid and their analogues [PDF]
SAGE Open MedicineBackground: In silico predictions are now being utilized in drug discovery and design to assess the physicochemical, pharmacokinetics, and safety properties of compounds at the beginning of the drug discovery process.
Melese Legesse Mitku +7 more
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مجله دانشکده پزشکی اصفهان, 2021 Background: Reactive oxygen species (ROS) are of the most important detrimental factors on sperm quality during freezing process, which increases the lipid peroxidation (LPO) of cell membranes.
Zahra Sadeghi +2 more
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Solution thermodynamics of aqueous nicotinic acid solutions in presence of tetrabutylammonium hydrogen sulphate [PDF]
Journal of the Serbian Chemical Society, 2013 In this study we investigated the effects of tetrabutylammonium hydrogen sulphate (Bu4NHSO4) on the solute-solute and solute-solvent interactions in the aqueous solutions of nicotinic acid in terms of apparent molar volumes (φV), standard partial ...
Sarkar Abhijit, Sinha Biswajit
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Nicotinic acid: a lipid-lowering agent with unrealized potential
The Egyptian Journal of Internal Medicine, 2014 Nicotinic acid is a well-known treatment for dyslipidemia in adults. This review article explored not only the role of nicotinic acid in dyslipidemia but also its role in hypertension and as a cardioprotective agent.
Samar H. Aboulsoud
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The distribution of charged amino acid residues and the Ca(2+) permeability of nicotinic acetylcholine receptors: a predictive model [PDF]
, 2017 Nicotinic acetylcholine receptors (nAChRs) are cation-selective ligand-gated ion channels exhibiting variable Ca(2+) permeability depending on their subunit composition.
Fucile, Sergio
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Journal of Animal Science and Technology, 2019 Vitamin B3 (niacin) is essential for all living cells and plays a central role in energy metabolism and oxidative phosphorylation. Vitamin B3, a water-soluble vitamin, is present in the form of nicotinic
Jale Çatak
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Biomolecules, 2015 Alcohol consumption causes nicotinic acid deficiency. The present study was undertaken to determine whether dietary nicotinic acid supplementation provides beneficial effects on alcohol-induced endotoxin signaling and the possible mechanisms at the gut ...
Wei Zhong +5 more
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