Results 31 to 40 of about 2,587,321 (283)

Influence of nicotinic acid on metabolism of cholesterol and triglycerides in man1

open access: yesJournal of Lipid Research, 1981
The mechanisms for the hypolipidemic action of nicotinic acid were examined in 12 patients with hyperlipidemia. Most patients were studied in the hospital on a metabolic ward.
S M Grundy, H Y Mok, L Zech, M Berman
doaj   +1 more source

Surface Interactions during the Removal of Emerging Contaminants by Hydrochar-Based Adsorbents

open access: yesMolecules, 2020
The aim of this work was to test activated carbons derived from hydrochars produced from sunflower stem, olive stone and walnut shells, as adsorbents for emerging contaminants in aqueous solution, namely fluoxetine and nicotinic acid.
Silvia Román   +4 more
doaj   +1 more source

Heterogenous Cholinergic Nicotinic Receptors in the CNS

open access: yes, 1988
Multiple nicotinic binding sites are found in mammalian brain. Several nicotinic agonists and antagonists have been used to characterize the nicotinic binding sites.
Nilsson, L   +9 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

EFFECT OF NICOTINIC ACID SUPPLEMENTATION ON PRODUCTION PERFORMANCE OF LACTATING COWS [PDF]

open access: yesJournal of Veterinary and Animal Sciences, 2008
The effect of dietary supple-mentation of nicotinic acid on milk yield and milk fat percentage was studied in twelve lactating cows allotted at random to treatments T1 and T2.
Renjith Gopal   +4 more
doaj  

Synthesis and characterization of ZnO/β-cyclodextrin/nicotinic acid nanocomposite and its biological and environmental application

open access: yesGreen Processing and Synthesis, 2023
In the present work, the disk-shaped zinc oxide (ZnO) nanoparticles were synthesized and functionalized with β-cyclodextrin (β-CD) and nicotinic acid (vitamin B3) using the wet co-precipitation method.
Alqahtani Mohammed S.   +3 more
doaj   +1 more source

Advances on the biosynthesis of pyridine rings

open access: yesEngineering Microbiology, 2023
Numerous studies have investigated the biosynthesis of pyridine heterocycles derived from nicotinic acid. However, metabolic pathways generating pyridine heterocycles in nature remain uninvestigated.
Carolina E. Portero   +2 more
doaj   +1 more source

Nicotinic Acid Restriction Enhances the Therapeutic Benefit of NAMPT Inhibition in Small-Cell Lung Cancer Models. [PDF]

open access: yesCancer Sci
Dietary NA restriction converts the effect of NAMPT inhibition from cytostatic to cytotoxic in SCLC in vivo. ABSTRACT Small‐cell lung cancer (SCLC) is an aggressive malignancy with limited therapeutic options. We previously showed that nicotinic acid riboside (NAR) sustains NAD biosynthesis in vivo and compensates for NAMPT inhibition in SCLC models ...
Tsurumi K   +12 more
europepmc   +2 more sources

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

EFFECTS OF LUDARTIN AND LEUKOMISIN ON THE ACUTE HYPERLIPIDEMIA MODEL INDUCED BY ETHANOL

open access: yesБюллетень сибирской медицины, 2015
Objective: study sesquiterpene lactones ludartin and leukomisin lipid-lowering properties on the model of acute hyperlipidemia induced by ethanol in rats.Material and methods. Rats during 7 days injected into the stomach ludartin and leukomisin in a dose
A. V. Ratkin   +5 more
doaj   +1 more source

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