Results 41 to 50 of about 55,760 (248)

CD177 Deficiency Defines a Stable Subtype of Human Neutrophil Granulocytes with Tumor Promoting Activity

open access: yesAdvanced Science, EarlyView.
Human neutrophils exist as two epigenetically imprinted subtypes defined by stable CD177 expression or absence — a ratio that persists across time, circadian rhythms, and inflammation. CD177− neutrophils display a distinct molecular landscape enriched in arginase 1 and lipid metabolism markers, accumulate in head‐and‐neck tumors, and associate with ...
Marcel Jung   +39 more
wiley   +1 more source

A intrigante bioquímica da niacina: uma revisão crítica

open access: yesQuímica Nova, 2011
Niacin (nicotinamide, nicotinic acid) interferes on homeostasis, DNA regulation, signaling and longevity. Nicotinic acid reduces synthesis of lipoproteins-apo-B and increases HDL.
Carlos Alberto Bastos de Maria   +1 more
doaj   +1 more source

SUPPRESSIVE EFFECTS of CERTAIN VITAMINS and ORGANIC ACIDS AGAINST Meloidogyne incognita on OKRA PLANT AND THEIR ROLE in IMPROVING HOST GROWTH UNDER GREENHOUSE CONDITIONS. [PDF]

open access: yesJournal of Plant Protection and Pathology, 2009
A pot experiment was conducted to determine the effects of six vitamins i.e. ascorbic acid, citric acid, folic acid, nicotinic acid, pyridoxine and thiamine in comparison with oxamyl against  Meloidogyne incognita infecting okra plant under greenhouse ...
A. Refaei
doaj   +1 more source

Exogenously applied nicotinic acid alleviates drought stress by enhancing morpho-physiological traits and antioxidant defense mechanisms in wheat

open access: yesEcotoxicology and Environmental Safety, 2023
Across the globe, the frequent occurrence of drought spells has significantly undermined the sustainability of modern high-input farming systems, particularly those focused on staple crops like wheat.
Nouman Khurshid   +11 more
doaj   +1 more source

Advancing the Design of High‐Efficiency Printable Hole‐Conductor‐Free Mesoscopic Perovskite Solar Cells Through Machine Learning

open access: yesAdvanced Science, EarlyView.
Based on the largest printable mesoscopic perovskite solar cells database we established, stacking model achieved precise PCE prediction (R2 = 0.73, MAE = 2.18%). Multiple experiments verified the accuracy of the model, which guided the fabrication of high‐PCE devices with an efficiency of 19.36%.
Hao Meng   +9 more
wiley   +1 more source

VALUE OF NICOTINIC ACID IN THE CURRENT CARDIOLOGY

open access: yesРациональная фармакотерапия в кардиологии, 2016
Statin intake is a standard in the treatment of patients with atherosclerosis nowadays. These drugs therapy associates with 30% risk reduction in mortality and coronary events.
E. P. Trukhacheva, M. V. Ezhov
doaj   +1 more source

Nicotinic acid receptor abnormalities in human skin cancer: implications for a role in epidermal differentiation. [PDF]

open access: yesPLoS ONE, 2011
Chronic UV skin exposure leads to epidermal differentiation defects in humans that can be largely restored by pharmacological doses of nicotinic acid. Nicotinic acid has been identified as a ligand for the human G-protein-coupled receptors GPR109A and ...
Yira Bermudez   +5 more
doaj   +1 more source

Neuron‐Targeted Exosomal Delivery of siRNA Against RIPK3 Slows Neurodegenerative Progression in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
Engineered exosomal siRNA delivery platform enables systemic, neuron‐targeted RNA transport across the blood–brain barrier. Surface functionalization with rabies virus glycoprotein‐derived peptide facilitates receptor‐mediated transcytosis, achieving efficient cytosolic delivery and robust gene silencing. Targeting RIPK3 suppresses necroptosis, reduces
Chi Zhang   +9 more
wiley   +1 more source

Targeted β‐Glucan‐Veiled Oral Apremilast Nanotherapy Modulates Key Dysbiosis‐Associated Gut Microbiota and Alleviates Ulcerative Colitis‐Associated Anxiety, Depression, and Neuropsychiatric Behaviors

open access: yesAdvanced Science, EarlyView.
This study introduces β‐glucan‐shielded apremilast laden nanomicelles that withstand gastrointestinal degradation, selectively accumulate in inflamed colon tissue, and modulate the microbiota–gut–brain axis. The formulation restores barrier integrity, reduces systemic and neuroinflammation, and improves anxiety‐ and depression‐like behaviors in colitis
Chandrashekhar Jori   +10 more
wiley   +1 more source

Comparison of efficacy of the phosphate binders nicotinic acid and sevelamer hydrochloride in hemodialysis patients

open access: yesSaudi Journal of Kidney Diseases and Transplantation, 2012
Hyperphosphatemia is a significant risk factor for the development of ectopic calcification and coronary artery diseases in patients on hemodialysis (HD), and must be controlled with the use of phosphate binders.
Farrokhlagha Ahmadi   +3 more
doaj   +1 more source

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