Results 61 to 70 of about 55,760 (248)
5-Trifluoromethoxy-substituted Nicotinic Acid, Nicotinamide and Related Compounds
Журнал органічної та фармацевтичної хіміїA practical and convenient method for synthesizing nicotinic acid and nicotinamide with the trifluoromethoxy group in position 5 of the ring has been developed.
Taras M. Sokolenko, Yurii L. Yagupolskii
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PLoS ONE, 2019 Bordetella bacteria are respiratory pathogens of humans, birds, and livestock. Bordetella pertussis the causative agent of whopping cough remains a significant health issue.
William T Booth +3 more
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Protective Effect of Phytic Acid in Cardiovascular Diseases: A Systematic Review
ChemFoodChem, EarlyView.ABSTRACT Cardiovascular diseases (CVDs) are a cluster of ailments that impact the heart and blood vessels and are a primary public health problem of mortality on a global scale. Phytic acid, a dietary constituent frequently present in foods like seeds, has been linked to many pharmacological attributes, including anti‐cancer, antioxidant, anti ...
Marta M. S. de Freitas Almeida +7 more
wiley +1 more source
EFFECT OF NICOTINIC ACID ON PLASMA AND BODY PROTEINS AND LIPIDS IN BROILERS [PDF]
Journal of Veterinary and Animal Sciences, 2002 Numerous attempts were made to reduce carcass fat in broilers by genetic, nutritional and pharmacological manipulation in the past years, so as to reduce the incidence of coronary heart disease in consumers of broiler meat. In this study an attempt was
P. Hariharanl, B. Gowrishanker
doaj
Trigonelline (-methylnicotinic acid) Biosynthesis and its Biological Role in Plants
Natural Product Communications, 2008 Trigonelline is synthesized from nicotinic acid in many plant species. This compound accumulates in seeds of leguminous plants and Coffea sp. The present article reviews the distribution of nicotinic acid conjugates and biosynthetic pathways of ...
Hiroshi Ashihara
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ChemFoodChem, EarlyView.Untargeted peptide profiling investigates how S. thermophilus, Lb. bulgaricus, and endogenous milk enzymes impact proteolysis during early‐stage milk fermentation. ≥ 3000 identified peptides show the strongest influence of LB on the peptide profile and number of bioactive peptides. Shorter peptides are mostly formed by LB and hydrolyzed by ST.
Eva Beck +6 more
wiley +1 more source
Chemistry – A European Journal, EarlyView.Levamisole is a common adulterant found in street‐distributed cocaine. Molecular baskets have been shown to form stable inclusion complexes with both substances. While levamisole inserts its benzene into the basket's cavity, cocaine utilizes its bicyclic ring for encapsulation.
Christopher T. Mortensen +7 more
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Pyridine Metabolism and Trigonelline Synthesis in Leaves of the Mangrove Legume trees ) and
Natural Product Communications, 2011 The aim of this study was to reveal the pyridine metabolism in leaves of two mangrove legumes, Derris indica (= Millettia pinnata or Pongamia pinnata ) and Caesalpinia crista.
Yuling Yin +2 more
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Nicotinic acid and DP1 blockade: studies in mouse models of atherosclerosis[S]
Journal of Lipid Research, 2013 The use of nicotinic acid to treat dyslipidemia is limited by induction of a “flushing” response, mediated in part by the interaction of prostaglandin D2 (PGD2) with its G-protein coupled receptor, DP1 (Ptgdr).
Alison M. Strack +25 more
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A Unified Approach for the Synthesis of Conformationally Locked and sp2‐sp3 Fused Hybrids
Chemistry – A European Journal, EarlyView.This study presents a systematic platform to build rigid sp2–sp3 hybrids via benzyne cycloadditions. Arene‑fused bicyclic oxa‐, aza‐, and carbocycles are converted into medicinally relevant amino acids and applied to Enalapril analogues synthesis. The hybrids combine aromatic interactions with 3D rigidity, tuning lipophilicity, pKa, and solubility ...
Ervis Saraci +8 more
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