Results 71 to 80 of about 61,560 (287)
Autism Research, EarlyView.ABSTRACT Irritability is a prevalent and impairing feature associated with autism, yet remains poorly understood, particularly in adults. Drawing heavily on insights translated from pediatric and transdiagnostic literatures, we propose that irritability in autistic individuals often reflects a psychophysiological stress or threat response, rooted in a ...
Hsiang‐Yuan Lin +3 more
wiley +1 more source
Paper electrophoresis of nicotinic acid derivatives
, 1959 The paper electrophoretic separation of nicotinic acid, nicotinamide, nicotinuric acid and N'-methylnicotinamide has been ...
Sarma, P. S. +2 more
core +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims Oral administration of (S)‐ketamine for treatment‐resistant depression (TRD), as alternative to the registered intranasal or off‐label intravenous administrations, has high potential. However, it is characterized by an extensive first‐pass metabolism, resulting in low (S)‐ketamine exposure and high levels of active metabolites, including (S ...
Marije E. Otto +5 more
wiley +1 more source
2-(Benzylcarbamoyl)nicotinic acid
Acta Crystallographica Section E, 2013 In the title compound, C14H12N2O3, the pyridine ring is twisted with respect to the phenyl ring and the carboxylic acid group at angles of 37.1 (5) and 8.1 (3)°, respectively; the phenyl ring forms a dihedral angle of 41.4 (1)°
Yan-Cao Mao +3 more
doaj +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims While pregnancy‐related changes in phase I enzyme activity are well‐documented, less is known about the impact on phase II enzymes. This study aimed to test the hypothesis that changes in the pharmacokinetics (PK) of uridine 5′‐diphosphoglucuronosyltransferase (UGT) substrates during pregnancy result from altered enzyme expression or activity ...
William Saffaf +6 more
wiley +1 more source
Thermal degradation kinetics of nicotinic acid, pantothenic acid and catechin derived from Averrhoa bilimbi fruits [PDF]
, 2015 Averrhoa bilimbi fruits contain appreciable amounts of polyphenolic compounds such as nicotinic acid, pantothenic acid and catechin, which can be recovered for use as food supplements.
Jolius, Gimbun +2 more
core +2 more sources
Nicotinamide Reverses the Warburg Effect in CHO Cell Culture
Biotechnology and Bioengineering, EarlyView.Abstract The Warburg effect, the preferential conversion of glucose‐derived pyruvat to lactate despite available oxygen, is a key feature of Chinese hamster ovary (CHO) cell culture. Lactate accumulation in recombinant protein‐producing cell culture is an inefficient usage of glucose, as well as being deleterious to cells.
James Morrissey +7 more
wiley +1 more source
The enthalpies of combustion and formation of nicotinic acid and creatinine
, 1975 The enthalpies of combustion of nicotinic acid and creatinine have been determined in an adiabatic rotating-bomb calorimeter. The enthalpies of formation have been obtained by combination of the experimental data with the accepted values for the ...
Johnson, Walter H.
core +1 more source
Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges
BMEMat, EarlyView.This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma +8 more
wiley +1 more source
, 2007 Anja Vogt1, Ursula Kassner1, Ulrike Hostalek2, Elisabeth Steinhagen-Thiessen11Charite-Universitatsmedizin Berlin, Germany; 2Merck KGaA, Darmstadt, GermanyAbstract: Low HDL-cholesterol (<1.02 mmol/L [40 mg/dL] in men or <1.29 mmol/L [50 mg ...
Ulrike Hostalek +3 more
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