Results 91 to 100 of about 61,560 (287)

The role of neuronal nicotinic acetylcholine receptors in central cardiovascular regulation.

open access: yes, 2007
The central effect of nicotine on cardiovascular regulation has been extensively studied. However, due to its unselective nature for nicotinic acetylcholine receptors (nAChR) the involvement of specific nAChRs at sites in the brain, in central nervous ...
Moore, C.
core  

Exploring Cerumen as an Alternative Matrix for Drug Detection and Quantification: Method Development and Application in Clinical Samples

open access: yesDrug Testing and Analysis, EarlyView.
An LC–MS/MS method was developed for the detection of 33 psychoactive medications in cerumen (earwax) and applied to the samples of 60 psychiatric inpatient volunteers. The findings highlighted the utility of cerumen as an innovative biospecimen in clinical toxicological analysis.
Dimitrios Phaedon Kevrekidis   +5 more
wiley   +1 more source

Trigonelline (-methylnicotinic acid) Biosynthesis and its Biological Role in Plants

open access: yesNatural Product Communications, 2008
Trigonelline is synthesized from nicotinic acid in many plant species. This compound accumulates in seeds of leguminous plants and Coffea sp. The present article reviews the distribution of nicotinic acid conjugates and biosynthetic pathways of ...
Hiroshi Ashihara
doaj   +1 more source

Receptor for Nicotinic Acid

open access: yes, 2006
Nicotinic acid belongs to the drugs with anti-hyperlipidemia effects. It lowers levels of both cholesterol and triglycerides and increases the level of HDL.
Suchánková, Marie
core  

AChBP-targeted alpha-conotoxin correlates distinct binding orientations with nAChR subtype selectivity

open access: yes, 2007
Neuronal nAChRs are a diverse family of pentameric ion channels with wide distribution throughout cells of the nervous and immune systems. However, the role of specific subtypes in normal and pathological states remains poorly understood due to the lack ...
Sixma, Titia K.   +46 more
core   +1 more source

Fhod3 in zebrafish supports myofibril stability during growth of embryonic skeletal muscle

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Actin filament organization in cardiomyocytes critically depends on the formin Fhod3, but a role for Fhod3 in skeletal muscle development has not yet been described. Results We demonstrate here that in zebrafish mutated for one of two fhod3 paralog genes, fhod3a, skeletal muscle of the trunk appears normal through 2 days post ...
Aubrie Russell   +3 more
wiley   +1 more source

EFFECT OF NICOTINIC ACID ON PLASMA AND BODY PROTEINS AND LIPIDS IN BROILERS [PDF]

open access: yesJournal of Veterinary and Animal Sciences, 2002
Numerous attempts were made to reduce carcass fat in broilers by genetic, nutritional and pharmacological manipulation in the past years, so as to reduce the incidence of coronary heart disease in consumers of broiler meat. In this study an attempt was
P. Hariharanl, B. Gowrishanker
doaj  

Structural mechanism for regulation of DNA binding of BpsR, a Bordetella regulator of biofilm formation, by 6-hydroxynicotinic acid.

open access: yesPLoS ONE, 2019
Bordetella bacteria are respiratory pathogens of humans, birds, and livestock. Bordetella pertussis the causative agent of whopping cough remains a significant health issue.
William T Booth   +3 more
doaj   +1 more source

Metabolic abnormalities and reprogramming in cats with naturally occurring hypertrophic cardiomyopathy

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1256-1270, April 2025.
Abstract Background and aims The heart is a metabolic organ rich in mitochondria. The failing heart reprograms to utilize different energy substrates, which increase its oxygen consumption. These adaptive changes contribute to increased oxidative stress.
Qinghong Li   +12 more
wiley   +1 more source

Variation of Nicotinic Acid and Nicotinic Acid Amide Content Found in the Home-made Burgers According to Roasting Time

open access: yes, 2019
departmental bulletin ...
岩井, 秀明   +7 more
core  

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