Results 101 to 110 of about 61,560 (287)

Capillary Electrophoresis With Amperometric Detection for Neurotransmitter Analysis: Principles, Electrode Materials, Methodologies, and Applications

open access: yesELECTROPHORESIS, EarlyView.
This review provides a comprehensive summary of monoamine neurotransmitter analysis by capillary electrophoresis with amperometric detection. Fundamental principles of amperometric detection, electrode positioning strategies, and approaches to high‐voltage decoupling are described, followed by a critical comparison of electrode materials, selection of ...
Petr Kubáň   +3 more
wiley   +1 more source

Pyridine Metabolism and Trigonelline Synthesis in Leaves of the Mangrove Legume trees ) and

open access: yesNatural Product Communications, 2011
The aim of this study was to reveal the pyridine metabolism in leaves of two mangrove legumes, Derris indica (= Millettia pinnata or Pongamia pinnata ) and Caesalpinia crista.
Yuling Yin   +2 more
doaj   +1 more source

Nicotinic acid and DP1 blockade: studies in mouse models of atherosclerosis[S]

open access: yesJournal of Lipid Research, 2013
The use of nicotinic acid to treat dyslipidemia is limited by induction of a “flushing” response, mediated in part by the interaction of prostaglandin D2 (PGD2) with its G-protein coupled receptor, DP1 (Ptgdr).
Alison M. Strack   +25 more
doaj   +1 more source

Effects of nicotinic acid on copper electrodeposition in acid sulphate

open access: yes, 2002
Initial stages of electrodeposition of copper on glassy carbon electrode from 0.8 mol (.) L-1 copper sulphate electrolyte solution containing 2.0 X 10(-2) Mol (.) L-1 nicotinic acid are studied using cyclic voltammetry and chronoamperometry.
周绍民   +11 more
core  

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

open access: yesEpilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang   +3 more
wiley   +1 more source

On the Generation of Bioactive Trigonelline Degradation Products upon Coffee Roasting and their Bioappearance after Coffee Consumption

open access: yesCzech Journal of Food Sciences, 2009
Besides caffeine, the betaine N-methyl nicotinic acid, also known as trigonelline, is commonly reported as the second most abundant alkaloid in raw coffee beans.
R. Lang, T. Hofmann
doaj   +1 more source

Cytotoxicity of 19 Pesticides in Rainbow Trout Gill, Liver, and Intestinal Cell Lines

open access: yesEnvironmental Toxicology and Chemistry, EarlyView.
Abstract The rainbow trout gill cell line (RTgill‐W1), via test guideline 249 of the Organisation for Economic Co‐operation and Development, has been established as a promising New Approach Methodology, although to advance confidence in the method more case studies are needed that: 1) expand our understanding of applicability domains (chemicals with ...
Sophie Emberley‐Korkmaz   +4 more
wiley   +1 more source

Pyridine nucleotide synthesis by rat adipose tissue in vitro

open access: yesJournal of Lipid Research, 1967
The synthesis of NAD and NADP by rat adipose tissue was measured in vitro. Nicotinamide-7-14C and NaH232PO4 were incorporated together into NAD with a 32P/14C ratio of 1.82 and nicotinic-7-14C acid and NaH232PO4 with a ratio of 1.94.
Richard W. Hanson, Zigmund Z. Ziporin
doaj   +1 more source

Body‐integrated photonic biosensors: Illuminating the path to active healthcare

open access: yesFlexMat, EarlyView.
Body‐integrated photonic biosensors are promising tools for active healthcare. These optical devices can be worn, implanted, or swallowed to monitor health signals continuously. This review introduces key sensing modalities, including fluorescence, colorimetry, SPR, LSPR, SERS, and light‐modulating materials.
Jiayue Gu   +10 more
wiley   +1 more source

Nicotinic acid and the prevention of coronary artery disease.

open access: yes, 2009
PURPOSE OF REVIEW: Nicotinic acid is the most potent treatment clinically available for lowering LDL cholesterol and VLDL cholesterol and raising HDL cholesterol.
Lee, JM, Digby, JE, Choudhury, RP
core   +1 more source

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