Environmental Toxicology, EarlyView.ABSTRACT Malathion (MAL) is a widely used organophosphate pesticide associated with hepatotoxicity through oxidative stress and apoptosis. Morin, a naturally occurring flavonoid, exhibits potent antioxidant and anti‐inflammatory properties. This study investigated oxidative stress, inflammatory, and apoptotic alterations induced by acute and subacute ...
Seval Yılmaz +3 more
wiley +1 more source
pH-Responsive Inorganic/Organic Nanohybrids System for Controlled Nicotinic Acid Drug Release. [PDF]
Molecules, 2022 Yu S +5 more
europepmc +1 more source
Psychedelic‐assisted treatment for substance use disorder: A narrative systematic review
Addiction, EarlyView.Abstract Background and aims This is the first systematic review of the extant literature on all major psychedelic‐assisted treatment for alcohol use disorder (AUD), tobacco use disorder (TUD) and other substance use disorders (SUD). We aimed to summarise the evidence for efficacy of psychedelic‐assisted treatment for AUD, TUD, and SUD; to evaluate its
Theodore Piper +7 more
wiley +1 more source
Bacterial PncA improves diet-induced NAFLD in mice by enabling the transition from nicotinamide to nicotinic acid. [PDF]
Commun Biol, 2023 Feng S, Guo L, Wang H, Yang S, Liu H.
europepmc +1 more source
Addiction, EarlyView.Abstract Background and Aims Psychedelic drugs may help treat alcohol use disorder (AUD). This study evaluated BPL‐003, a novel intranasal powder formulation of 5‐methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT) benzoate salt, in people with moderate–severe AUD enrolled in a standard of care, 10‐week programme of relapse‐prevention oriented Cognitive ...
John Marsden +10 more
wiley +1 more source
The effects of NAD+ precursor (nicotinic acid and nicotinamide) supplementation on weight loss and related hormones: a systematic review and meta-regression analysis of randomized controlled trials. [PDF]
Front Nutr, 2023 Baichuan Y +5 more
europepmc +1 more source
Addiction, EarlyView.Abstract Aim Our primary aim was to conduct a network meta‐analysis (NMA) for the effectiveness, safety and acceptability of all psychosocial interventions and all pharmacotherapies for cannabis use disorder (CUD). Methods We conducted a NMA of studies identified from two completed systematic reviews examining the effectiveness, safety and ...
Monika Halicka +6 more
wiley +1 more source
An improved process for synthesis of nicotinic acid using hyper induced whole cell nitrilase of Gordonia terrae MTCC8139. [PDF]
3 Biotech, 2022 Monika, Sheetal, Thakur N, Bhalla TC.
europepmc +1 more source
Beyond abstinence: Redefining success in cannabis use disorder treatment
Addiction, EarlyView.Abstract Background Over two decades of pharmacotherapy research has yet to yield a consistently effective medication for cannabis use disorder (CUD), in part because clinical trials have frequently prioritized abstinence as a primary or key endpoint.
Tobias B. Atkin +3 more
wiley +1 more source
Synthesis and structure of a binuclear calcium nitrate coordination complex with bridging zwitterionic nicotinic acid. [PDF]
Acta Crystallogr E Crystallogr CommunBurkitbaeva G +7 more
europepmc +1 more source