Results 81 to 90 of about 61,560 (287)

Nicotinic acid transport via MCT4.

, 2015
(A) MCT4 cRNA-injected or water-injected oocytes were incubated for 5 min at 25°C with 10 nM nicotinic acid (0.5 μCi/ml) at pH 5.5 or 7.5. Data are presented as means±S.E. of three experiments.
Yuya Futagi (440139), Hiroaki Yamaguchi (440141), Jiro Ogura (440140), Shotaro Sasaki (440138), Masaki Kobayashi (262088), Ken Iseki (440142)   +5 more
core   +1 more source

Inclusion Complexations of Levamisole and Cocaine With Molecular Baskets. Fluorescence Displacement Assay for Detection of Cocaine and Its Adulterant Levamisole in Aqueous Media

Chemistry – A European Journal, EarlyView.
Levamisole is a common adulterant found in street‐distributed cocaine. Molecular baskets have been shown to form stable inclusion complexes with both substances. While levamisole inserts its benzene into the basket's cavity, cocaine utilizes its bicyclic ring for encapsulation.
Christopher T. Mortensen, Carson E. Ward, Nitesh Kumar, Logan Willemann, Ryan Lutz, Kailey Hughes, Zheng Zheng, Jovica D. Badjić   +7 more
wiley   +1 more source

Genomic Insights Into Risperidone Treatment Outcomes in Children and Adolescents: Experience From a Psychiatric Hospital Serving Rural Youth

Clinical Pharmacology &Therapeutics, EarlyView.
Risperidone is a commonly used antipsychotic for treating psychiatric illness in children and adolescents. There is a large variability in risperidone response and discontinuation rates remain high. Pharmacogenomics offers the opportunity to improve risperidone outcomes, yet studies in pediatric populations are limited.
Jack W. Staples, Shayna R. Killam, Karen E. Brown, Rachel Dalton, Elizabeth Sather, Qiang Chen, Joshua Loveland, Corbin Schwanke, Abdallah F. Elias, Kristin L. Bigos, Erica L. Woodahl   +10 more
wiley   +1 more source

Synthesis, Characterization, and Thermodynamic Study of the Solid State Coordination Compound Ni(Nic)2•H2O(s) (Nic = Nicotinic Acid)

, 2008
Synthesis, Characterization, and Thermodynamic Study of the Solid State Coordination Compound Ni(Nic)2•H2O(s) (Nic = Nicotinic ...
孙立贤, 谭志诚, 邸友莹
core  

Langerhans Cells Release Prostaglandin D2 in Response to Nicotinic Acid

, 2006
Nicotinic acid, used for atherosclerosis treatment, has an adverse effect of skin flushing. The flushing mechanism, thought to be caused by the release of prostaglandin D2 (PGD2), is not well understood.
Dominic P. Behan, Daniel T. Connolly, Hakak, Yaron, Gaidarov, Ibragim, Maciejewski-Lenoir, Dominique, Richman, Jeremy G., Behan, Dominic P., Jeremy G. Richman, Dominique Maciejewski-Lenoir, Yaron Hakak, Connolly, Daniel T., Ibragim Gaidarov   +11 more
core   +1 more source

Uncovering Coenzyme Q10‐Related Genetic Determinants of Statin‐Associated Muscle Symptoms: Evidence from the UK Biobank and the All of Us Research Program

Clinical Pharmacology &Therapeutics, EarlyView.
Statin‐associated muscle symptoms (SAMS) are frequent adverse effects of statin therapy and have been hypothesized to result from impaired coenzyme Q10 (CoQ10) biosynthesis. Although genetic determinants of CoQ10 levels have been reported, genome‐wide association studies (GWASs) conducted specifically in statin users are lacking. Moreover, direct CoQ10
Da Hoon Lee, Yoon‐A Park, Yubin Song, Ji‐Min Han, Kyung Hee Choi, Myeong Gyu Kim, Hye Sun Gwak   +6 more
wiley   +1 more source

Effects of the associations of morin - nicotinic acid and quercetin - nicotinic acid in the lipidic control.

, 1999
A aterosclerose pode ser considerada uma doença na circulação coronariana. O presente trabalho estuda a ação da quercetina, morina, ácido nicotínico de maneira isolada e em associação envolvendo quercetina + ácido nicotínico e morina + ácido nicotínico ...
Oliveira, Tânia Toledo de, Nagem, Tanus Jorge, Oliveira, Maria Goreti de Almeida, Santos, Ricardo K. F., Soares, José Francisco, Pinto, Aloísio da Silva   +5 more
core   +1 more source

Age-related increase of kynurenic acid in human cerebrospinal fluid-IgG and beta(2)-microglobulin changes

, 2005
Kynurenic acid (KYNA) is an endogenous metabolite in the kynurenine pathway of tryptophan degradation and is an antagonist at the glycine site of the N-methyl-D-aspartate as well as at the alpha 7 nicotinic cholinergic receptors. In the brain tissue KYNA
Newcombe, J, Kalina, P, Kepplinger, B, Baran, H, Ferraz-Leite, H, Kainz, A   +5 more
core  

Spectroscopic Characterization of Disulfiram and Nicotinic Acid after Biofield Treatment [PDF]

, 2015
Disulfiram is being used clinically as an aid in chronic alcoholism, while nicotinic acid is one of a B-complex vitamin that has cholesterol lowering activity.
Jana, Snehasis, Trivedi, Mahendra Kumar, Trivedi, Dahryn, Branton, Alice, Nayak, Gopal, Bairwa, Khemraj   +5 more
core   +1 more source

Investigation of the In Vitro and In Vivo Metabolism and μ‐Opioid Receptor Affinity of the Nitazene N‐Pyrrolidino Fluetonitazene

Drug Testing and Analysis, EarlyView.
Eight metabolites for N‐pyrrolidino fluetonitazene were identified in vitro, three of which (M2, M6 and M8) were present in an authentic urine sample. M2 was the most abundant in vivo metabolite and is a common marker metabolite of nitazepyne‐type substances.
Severin Zemp, Gaia Alluisetti, Wolfgang Weinmann, Bettina Schrag, Frank Sporkert, Maurine Leclerc, Katharina Elisabeth Grafinger   +6 more
wiley   +1 more source