Results 81 to 90 of about 106,501 (287)
British Journal of Clinical Pharmacology, EarlyView.Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale +5 more
wiley +1 more source
Trigonelline (-methylnicotinic acid) Biosynthesis and its Biological Role in Plants
Natural Product Communications, 2008 Trigonelline is synthesized from nicotinic acid in many plant species. This compound accumulates in seeds of leguminous plants and Coffea sp. The present article reviews the distribution of nicotinic acid conjugates and biosynthetic pathways of ...
Hiroshi Ashihara
doaj +1 more source
Sensing a Bacillis anthracis biomarker with well-known OLED emitter EuTta3Phen [PDF]
, 2016 Dipicolinic acid (DPA) is a distinctive biomarker for bacterial spores. Here, we present the successful demonstration of dramatic Switch-OFF sensing of DPA using an easily synthesised Eu(III) phosphor applied primarily in light-emitting devices.
Aspinall +18 more
core +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims Oral administration of (S)‐ketamine for treatment‐resistant depression (TRD), as alternative to the registered intranasal or off‐label intravenous administrations, has high potential. However, it is characterized by an extensive first‐pass metabolism, resulting in low (S)‐ketamine exposure and high levels of active metabolites, including (S ...
Marije E. Otto +5 more
wiley +1 more source
5-Trifluoromethoxy-substituted Nicotinic Acid, Nicotinamide and Related Compounds
Журнал органічної та фармацевтичної хіміїA practical and convenient method for synthesizing nicotinic acid and nicotinamide with the trifluoromethoxy group in position 5 of the ring has been developed.
Taras M. Sokolenko, Yurii L. Yagupolskii
doaj +1 more source
EFFECT OF NICOTINIC ACID ON PLASMA AND BODY PROTEINS AND LIPIDS IN BROILERS [PDF]
Journal of Veterinary and Animal Sciences, 2002 Numerous attempts were made to reduce carcass fat in broilers by genetic, nutritional and pharmacological manipulation in the past years, so as to reduce the incidence of coronary heart disease in consumers of broiler meat. In this study an attempt was
P. Hariharanl, B. Gowrishanker
doaj
PLoS ONE, 2019 Bordetella bacteria are respiratory pathogens of humans, birds, and livestock. Bordetella pertussis the causative agent of whopping cough remains a significant health issue.
William T Booth +3 more
doaj +1 more source
The effect of 3-indoleacetic acid on the response of Lactobacillus arabinosus 17-5 to nicotinamide [PDF]
, 1949 Lactobacillus arabinosus 17-5 has been widely used as an assay organism for nicotinic acid (NA) since the development of the method by Snell and Wright (1). Although it has been realized that other substances present in tissue extracts may interfere with
Galston, Arthur W., Hand, Margery E.
core
British Journal of Clinical Pharmacology, EarlyView.Aims While pregnancy‐related changes in phase I enzyme activity are well‐documented, less is known about the impact on phase II enzymes. This study aimed to test the hypothesis that changes in the pharmacokinetics (PK) of uridine 5′‐diphosphoglucuronosyltransferase (UGT) substrates during pregnancy result from altered enzyme expression or activity ...
William Saffaf +6 more
wiley +1 more source
Nicotinic acid and DP1 blockade: studies in mouse models of atherosclerosis[S]
Journal of Lipid Research, 2013 The use of nicotinic acid to treat dyslipidemia is limited by induction of a “flushing” response, mediated in part by the interaction of prostaglandin D2 (PGD2) with its G-protein coupled receptor, DP1 (Ptgdr).
Alison M. Strack +25 more
doaj +1 more source