Enzymatic approaches to nicotinic acid synthesis: recent advances and future prospects [PDF]
Biocatalyst-mediated reactions have led to revolutionary transformations in the organic synthesis of pharmaceuticals, drugs, and other chemicals.
Rahul Vikram Singh +5 more
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VALUE OF NICOTINIC ACID IN THE CURRENT CARDIOLOGY [PDF]
Statin intake is a standard in the treatment of patients with atherosclerosis nowadays. These drugs therapy associates with 30% risk reduction in mortality and coronary events.
E. P. Trukhacheva, M. V. Ezhov
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In silico prediction of some pharmacokinetic, safety, biological activity and molecular docking studies of 1-piperazine indole hybrid with nicotinic amide and nicotinic acid and their analogues [PDF]
Background: In silico predictions are now being utilized in drug discovery and design to assess the physicochemical, pharmacokinetics, and safety properties of compounds at the beginning of the drug discovery process.
Melese Legesse Mitku +7 more
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5-Trifluoromethoxy-substituted Nicotinic Acid, Nicotinamide and Related Compounds [PDF]
A practical and convenient method for synthesizing nicotinic acid and nicotinamide with the trifluoromethoxy group in position 5 of the ring has been developed.
Taras M. Sokolenko, Yurii L. Yagupolskii
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A fascinating class of nicotinic-acid-ornamented tetrameric rare-earth (RE)-substituted phospho(III)tungstates [NH2(CH3)2]10Na4H8[RE2(NA)(HNA)(H2O)6(W2O4)(β-H2P2IIIW13O49)(α-HPIIIW9O33)]2·22 H2O [RE = Nd3+ (1-Nd), Tb3+ (2-Tb), Dy3+ (3-Dy), Ho3+ (4 ...
Lijuan Chen +11 more
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Role of GPR109A Receptor in the Efficacy of Nicotinic Acid
Nicotinic acid is used to treat dyslipidemia from the past few decades. Nicotinic acid has the capability to increase plasma HDL cholesterol concentration, and so it is being used as a potential pharmacological agent.
Neeraj Kumar +5 more
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Scientific Opinion on the safety and efficacy of niacin (nicotinic acid and nicotinamide) as a feed additive for all animal species based on a dossier submitted by Vertellus Specialties Belgium BV [PDF]
<p>The term ‘niacin’ is used as a generic description of nicotinic acid and nicotinamide with pyridine as the basic structure. Nicotinic acid and nicotinamide function mainly as precursors of the co-enzymes NAD and NADP.
EFSA Panel on Additives and Products or Substances used in Animal Feed
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Cloning and characterization of the hamster and guinea pig nicotinic acid receptors
In this study, we present the identification and characterization of hamster and guinea pig nicotinic acid receptors. The hamster receptor shares ∼80–90% identity with the nucleotide and amino acid sequences of human, mouse, and rat receptors. The guinea
April Smith Torhan +3 more
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Effect of in ovo Injection of Nicotonic Acid, Pantothenic Acid or Folic Acid on Immune System and Growth of Broiler Chickens [PDF]
BACKGROUND: In ovo injection of nutrients as an early feeding method in birds directly supplies the nu- trients to the developing embryo. OBJECTIVES: This study was designed to evaluate the effects of in ovo injection of nicotonic acid, panto- thenic ...
Asaad Parnian +4 more
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The influence of exogenous growth regulators on the cannabinoid content and the main selection traits of hemp (Cannabis sativa L. ssp. Sativa) [PDF]
Hemp (Cannabis sativa L.) is a species sensitive to the influence of exogenous growth regulators, both in the treatment of vegetative plant tissues and in vitro culture. 1-naphthylacetic acid, indole-3-acetic acid, 2,4-dichlorophenoxyacetic acid, kinetin,
Mishchenko Serhii V. +5 more
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