Methods to Produce Nicotinic Acid with Potential Industrial Applications [PDF]
Materials, 2022 Nicotinic acid is a naturally occurring pyridine carboxylic acid, contained in vitamin PP, an essential nutrient for humans and animals, and used as an antipelagic agent. Nicotinic acid can be made from tryptophan by plants and animals but is usually not
Dawid Lisicki +2 more
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Enzymatic approaches to nicotinic acid synthesis: recent advances and future prospects [PDF]
Frontiers in Bioengineering and BiotechnologyBiocatalyst-mediated reactions have led to revolutionary transformations in the organic synthesis of pharmaceuticals, drugs, and other chemicals.
Rahul Vikram Singh +5 more
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Nicotinic acid: a lipid-lowering agent with unrealized potential
The Egyptian Journal of Internal Medicine, 2014 Nicotinic acid is a well-known treatment for dyslipidemia in adults. This review article explored not only the role of nicotinic acid in dyslipidemia but also its role in hypertension and as a cardioprotective agent.
Samar H. Aboulsoud
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In silico prediction of some pharmacokinetic, safety, biological activity and molecular docking studies of 1-piperazine indole hybrid with nicotinic amide and nicotinic acid and their analogues [PDF]
SAGE Open MedicineBackground: In silico predictions are now being utilized in drug discovery and design to assess the physicochemical, pharmacokinetics, and safety properties of compounds at the beginning of the drug discovery process.
Melese Legesse Mitku +7 more
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Nicotinic acid mononucleotide is an allosteric SARM1 inhibitor promoting axonal protection. [PDF]
Exp Neurol, 2021 SARM1 is an inducible NAD(+) hydrolase that is the central executioner of pathological axon loss. Recently, we elucidated the molecular mechanism of SARM1 activation, demonstrating that SARM1 is a metabolic sensor regulated by the levels of NAD(+) and ...
Sasaki Y +7 more
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Nicotinic acid in nanocontainers. Encapsulation and release from ion exchangers [PDF]
ADMET and DMPK, 2019 The paper is devoted to the study of the ion exchange encapsulation of nicotinic acid in nanocontainers on polymer matrices. Dowex-50 cation exchanger, sulphonated polymer based on metacyclophanoctol, polymer zirconium phosphate, and strongly basic Dowex-
Heinrich Altshuler +6 more
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Journal of Chemistry, 2020 The influence of altitude on caffeine, 5-caffeoylquinic acid (5-CQA), and nicotinic acid contents of Arabica coffee varieties grown in Southwest Ethiopia was investigated.
Bealu Girma, Abera Gure, Feyisa Wedajo
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VALUE OF NICOTINIC ACID IN THE CURRENT CARDIOLOGY
Рациональная фармакотерапия в кардиологии, 2016 Statin intake is a standard in the treatment of patients with atherosclerosis nowadays. These drugs therapy associates with 30% risk reduction in mortality and coronary events.
E. P. Trukhacheva, M. V. Ezhov
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5-Trifluoromethoxy-substituted Nicotinic Acid, Nicotinamide and Related Compounds
Журнал органічної та фармацевтичної хіміїA practical and convenient method for synthesizing nicotinic acid and nicotinamide with the trifluoromethoxy group in position 5 of the ring has been developed.
Taras M. Sokolenko, Yurii L. Yagupolskii
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Pharmacology Biochemistry and Behavior, 2012 Although in vitro studies have shown that nicotinic acid inhibits some aspects of the inflammatory response, a reduced number of in vivo studies have investigated this activity.
Marcio M Coelho
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