Results 151 to 160 of about 329,742 (333)

Modulating Neurotoxic Effects of Prenatal Chlorpyrifos Exposure Through Probiotic and Vitamin D Gestational Supplementation: Unexpected Effects on Neurodevelopment and Sociability

Food Frontiers, EarlyView.
This study investigates whether gestational probiotic and vitamin D supplementation can mitigate CPF effects in Wistar rats. While supplementation did not reverse CPF‐induced deficits, it induced notable neurodevelopmental changes in control animals, underscoring the need for further research on prenatal supplementation safety.
Mario Coca, Cristian Perez‐Fernandez, Ana C. Abreu, Ana M. Salmerón, Miguel Morales‐Navas, Diego Ruiz‐Sobremazas, Teresa Colomina, Ignacio Fernández, Fernando Sanchez‐Santed   +8 more
wiley   +1 more source

Vanillin Modulates the Sedative Effect of Diazepam, Possibly Through GABAergic Interaction Pathways in Thiopental Sodium‐Induced Sleeping Mice

Food Safety and Health, EarlyView.
Vanillin showed moderate sedative and modulatory synergistic activities on diazepam in thiopental sodium‐induced sleeping mice. These effects are implicated with GABAergic intervention. ABSTRACT Insomnia is a common sleep disorder affecting approximately 10% of adults.
Salehin Sheikh, Md. Shimul Bhuia, Raihan Chowdhury, Md. Sakib Al Hasan, Most. Israt Jahan Oni, Imam Hossen Rakib, Mir Imran Alim, Jakia Sultana, Muhammad Torequl Islam   +8 more
wiley   +1 more source

The Role of Loneliness and Ostracism in Adolescents’ Psychological Well‐Being and Substance Use: Family and Teacher Support as Moderators

Journal of Adolescence, EarlyView.
ABSTRACT Introduction This study examined the role of loneliness (social and emotional) and ostracism in adolescents’ psychological well‐being (positive mental health and psychological symptoms) and substance use. Perceived teacher and family support and grade level were examined as moderators in these associations.
Mari Tunkkari, Noona Kiuru, Niina Junttila, Leena Paakkari, Nelli Lyyra   +4 more
wiley   +1 more source

Structural and temporal basis for agonism in the α4β2 nicotinic acetylcholine receptor [PDF]

, 2022
A. Sofia F. Oliveira, Isabel Bermúdez, Timothy Gallagher, Susan Wonnacott, Giovanni Ciccotti, Richard B. Sessions, Adrian J. Mulholland   +6 more
openalex   +1 more source

Assessment of the Effects of Cigarette Smoke on the Renal Morphology of WISTAR Rats

Journal of Applied Toxicology, EarlyView.
ABSTRACT Smoking is a major public health concern worldwide. The toxic components of cigarettes, such as nicotine, can cause abuse, dependence, and tissue damage. This study aimed to evaluate the effects of exposure to cigarette smoke on the renal morphology of Wistar rats.
Cristiane Gomes Fernandes Freire, Luana Aparecida Cunha, Mateus Andrade Stecca, Isabele Masson de Brito, Rafaella Riccio da Silva, Thiago Donizeth da Silva, Margarida Pereira Santos, Márcia Cristina Bizinotto de Assunção, Geraldo José Medeiros Fernandes, Evelise Aline Soares   +9 more
wiley   +1 more source

Perinatal Exposure to the Neonicotinoid Thiacloprid Impacts Transcription of Neuroplasticity and Neuroendocrine Markers in Mice but Not in the Zebrafish Model

Journal of Applied Toxicology, EarlyView.
ABSTRACT Neonicotinoids are widely used insecticides in agriculture, aquaculture, pet care, and urban pest control. Initially developed to selectively target the insect cholinergic system, their extensive use has raised concerns about adverse effects on nontarget vertebrates.
Kirthana Kunikullaya U, Zuzanna M. Baran, Pascal Coumailleau, Laetitia Guillot, Harry W. M. Steinbusch, Fatima Smagulova, Thierry D. Charlier   +6 more
wiley   +1 more source

5-Trifluoromethoxy-substituted Nicotinic Acid, Nicotinamide and Related Compounds

Журнал органічної та фармацевтичної хімії
A practical and convenient method for synthesizing nicotinic acid and nicotinamide with the trifluoromethoxy group in position 5 of the ring has been developed.
Taras M. Sokolenko, Yurii L. Yagupolskii
doaj   +1 more source

Genetic polymorphisms in human CYP2A6 gene causing impaired nicotine metabolism [PDF]

, 2002
Ryoko Yoshida, Miki Nakajima, Yuki Watanabe, Jun‐Tack Kwon, Tsuyoshi Yokoi   +4 more
openalex   +1 more source

Evaluation of Acute Exposure to Combustible and Novel Tobacco Products Using an In Vitro Human Airway Organ Tissue Equivalent Model

Journal of Applied Toxicology, EarlyView.
ABSTRACT Despite the well‐known risks of tobacco use, tobacco exposure remains a major contributor to morbidity and mortality worldwide. Although cigarette use has declined, the popularity of novel tobacco products (NTPs), such as electronic cigarettes (ECs) and heated tobacco products (HTPs), has increased.
Timothy S. Leach, Steven Albertson, Phillip W. Clapp, Vikram Surendran, Trang Simon, Eric C. Donny, Stephen J. Walker, Anthony Atala, Sean V. Murphy   +8 more
wiley   +1 more source

Nicotinic acetylcholine receptors in neuropathic and inflammatory pain

FEBS Letters, 2018
Arik J. Hone, J. M. McIntosh
semanticscholar   +1 more source