Results 131 to 140 of about 156,732 (304)

Brain Cholinergic Mechanisms

open access: yesFrontiers in Synaptic Neuroscience, 2015
Sukumar eVijayaraghavan, Geeta eSharma
doaj   +1 more source

Nicotine as Therapy

open access: yesPLoS Biology, 2004
In daily use for centuries by hundreds of millions of people, nicotine has only lately been investigated for its therapeutic potential in a long list of common ...
openaire   +4 more sources

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

open access: yesEpilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang   +3 more
wiley   +1 more source

Long‐Term Effectiveness of Inpatient and Day‐Hospital Treatment of Eating Disorders in Departments of Psychosomatic Medicine and Psychotherapy in Germany

open access: yesEuropean Eating Disorders Review, EarlyView.
ABSTRACT Background There is ample evidence on the efficacy of different therapeutic approaches in treating eating disorders. Yet, studies on the effectiveness of inpatient/day‐hospital treatment of eating disorders are rare. Method Data were retrieved from a naturalistic multi‐center effectiveness study of inpatient and day‐hospital treatment in ...
Magdalena Pape   +42 more
wiley   +1 more source

Cytotoxicity of 19 Pesticides in Rainbow Trout Gill, Liver, and Intestinal Cell Lines

open access: yesEnvironmental Toxicology and Chemistry, EarlyView.
Abstract The rainbow trout gill cell line (RTgill‐W1), via test guideline 249 of the Organisation for Economic Co‐operation and Development, has been established as a promising New Approach Methodology, although to advance confidence in the method more case studies are needed that: 1) expand our understanding of applicability domains (chemicals with ...
Sophie Emberley‐Korkmaz   +4 more
wiley   +1 more source

5-Trifluoromethoxy-substituted Nicotinic Acid, Nicotinamide and Related Compounds

open access: yesЖурнал органічної та фармацевтичної хімії
A practical and convenient method for synthesizing nicotinic acid and nicotinamide with the trifluoromethoxy group in position 5 of the ring has been developed.
Taras M. Sokolenko, Yurii L. Yagupolskii
doaj   +1 more source

Effects of inhalation of Freon 113 on laboratory animals [PDF]

open access: yes
Four monkeys, 8 dogs, 40 mice, and 50 rats were exposed continuously to 2000 ppm Freon 113 in a Thomas Dome for 14 days. This exposure produced no mortalities nor adverse symptomology.
Back, K. C.   +3 more
core   +1 more source

Body‐integrated photonic biosensors: Illuminating the path to active healthcare

open access: yesFlexMat, EarlyView.
Body‐integrated photonic biosensors are promising tools for active healthcare. These optical devices can be worn, implanted, or swallowed to monitor health signals continuously. This review introduces key sensing modalities, including fluorescence, colorimetry, SPR, LSPR, SERS, and light‐modulating materials.
Jiayue Gu   +10 more
wiley   +1 more source

Beyond Gut Modulation: A Critical Review of the Therapeutic Potential, Safety, and Clinical Prospects of Natural Polysaccharides for IBD

open access: yesFood Safety and Health, EarlyView.
In this review, we critically summarized the application of natural polysaccharides (NPs) for the treatment of IBD. This approach combines, in a unique way (right), the basic structure–activity relationships of NPs from different origins (left) with their multipronged mode of action, which involves modulation of the gut microbiota and other ...
Felix Danso   +3 more
wiley   +1 more source

How do US Adults Who Vape Choose Among Different E‐Cigarette (EC) Models and Cigarettes in Response to Prices and Taxes

open access: yesHealth Economics, EarlyView.
ABSTRACT States continue to impose E‐Cigarette (EC) taxes without clear evidence of the cross‐price elasticities between multiple EC types and between ECs and cigarettes. Moreover, existing literature focused on EC sales or prevalence outcomes instead of consumption units of various EC types.
Shaoying Ma   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy