Results 161 to 170 of about 329,742 (333)

Reversal of Fentanyl‐Induced Respiratory Depression in Healthy Subjects by Intramuscular Nalmefene Administered by Auto‐Injector Versus Intranasal Naloxone

The Journal of Clinical Pharmacology, EarlyView.
Abstract As illegally made fentanyl and congeners continue to drive overdose deaths in the US, experts have called for stronger and longer‐lasting antagonists. A randomized, 4‐period, 2‐treatment crossover replicate‐design study in healthy moderately‐experienced opioid users (n = 24) evaluated the reversal of opioid‐induced respiratory depression (OIRD)
Alessandra Cipriano, Ellie He, Manjunath Shet, Glen Apseloff, Stephen C. Harris   +4 more
wiley   +1 more source

Nicotinic Receptor-Mediated Reduction in l-DOPA-Induced Dyskinesias May Occur via Desensitization [PDF]

, 2010
Tanuja Bordia, Carla Cristian Campos, J. Michael McIntosh, Maryka Quik   +3 more
openalex   +1 more source

A Randomized Crossover Clinical Study to Assess the Effect of Oral Nicotine Pouches Used for Different Durations on Plasma Nicotine Pharmacokinetics in Healthy Oral Pouch Consumers

The Journal of Clinical Pharmacology, EarlyView.
Abstract Oral nicotine pouches (NPs), although addictive and not risk‐free, have potential application for a tobacco harm reduction approach. This study aims to further characterize their ability to deliver nicotine effectively. This randomized seven‐way crossover PK study in healthy oral pouch consumers evaluated 11 and 20 mg NPs used for 10, 20, and ...
David Azzopardi, Elaine Brown, Filimon Meichanetzidis, Stacy Fiebelkorn, Linsey E. Haswell, George Hardie, Michael McEwan   +6 more
wiley   +1 more source

Evaluation of the protective effects of icariin on nicotine-induced reproductive toxicity in male mouse –a pilot study [PDF]

, 2020
Guochao Ni, Xuhui Zhang, Seth Yaw Afedo, Rui Rong   +3 more
openalex   +1 more source

Prognostic Factors for Complications Following Ultrasound‐Guided Percutaneous Kidney Biopsy: A 7‐Year Retrospective Study

Journal of Clinical Ultrasound, EarlyView.
Complications were common but mostly minor following ultrasound‐guided percutaneous kidney biopsy. Older age, obesity, and smoking were independently associated with a reduced risk of complications, including hematoma. These findings highlight the overall safety of the procedure and support individualized risk assessment based on patient ...
Sehyun Jung, Seunghye Lee, Hyejin Jeon, Hani Jang, Se‐Ho Chang, Hyun‐Jung Kim   +5 more
wiley   +1 more source

Stress Management for Students in Dental Education: a Scoping Review

Journal of Dental Education, EarlyView.
ABSTRACT Stress in the university setting is well‐reported. This scoping review aims to synthesize and evaluate the current literature on stress in dental education to understand stress and stress‐management interventions that have been trialed with dental students.
Gillian D. Boehm, Jessica R. L. Lieffers, Sheryl Mills, Amrinderbir Singh   +3 more
wiley   +1 more source

Economic demand analysis of within-session dose-reduction during nicotine self-administration

, 2019
Gregory L. Powell, Gabriella Cabrera-Brown, Mark D. Namba, Janet L. Neisewander, Julie A. Marusich, Joshua S. Beckmann, Cassandra D. Gipson   +6 more
openalex   +2 more sources

Safety and Efficacy of Nicotine Replacement Therapy in the Perioperative Period: A Narrative Review [PDF]

, 2015
Margaret Nolan, David O. Warner
openalex   +1 more source

A “One‐Pot” Metal‐Free Synthesis and Evaluation of Antiproliferative Activity of Diversely Functionalized Pyrrolidine‐2‐Ones

Journal of Heterocyclic Chemistry, EarlyView.
A new “one‐pot” metal‐free stereoselective method for the synthesis of novel diversely functionalized pyrrolidine‐2‐ones from N‐alkyl‐ or N‐arylsulfonamidoacetophenones was developed. The majority of obtained compounds possess low micromolar antiproliferative activities.
Samuel Dick, Matija Bekic, David Meuter, Gary Angles, Victoria Sena, Tatiana Timofeeva, Arturo Lopez Villalobos, Liliya V. Frolova   +7 more
wiley   +1 more source

Hippocampal and Insular Response to Smoking-Related Environments: Neuroimaging Evidence for Drug-Context Effects in Nicotine Dependence [PDF]

, 2015
F. Joseph McClernon, Cynthia A. Conklin, Rachel V. Kozink, R. Alison Adcock, Maggie M. Sweitzer, Merideth A. Addicott, Ying‐hui Chou, Nan‐kuei Chen, Matthew Hallyburton, Anthony M DeVito   +9 more
openalex   +1 more source