Results 181 to 190 of about 156,732 (304)

Multi‐Targeting Ligands as Prospective Therapeutics for Alzheimer's Disease, a Prevalent Neurodegenerative Disorder: Mechanistic Insights, Emerging Targets and Drug Discovery Campaigns

Medicinal Research Reviews, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur, Mandeep Rana, Sakshi Vanjani, Kei‐Chi Liou, Rajeev Taliyan, Kunal Nepali, Chih‐Hao Yang   +6 more
wiley   +1 more source

Canal Cholesteatoma Presentation and Management: A Systematic Review and Meta‐Analysis

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To evaluate current understanding of external auditory canal cholesteatoma (EACC), its symptomatic burden, clinical features, diagnostic approach, and management strategies to reduce delays in diagnosis. Data Sources PubMed, CINAHL, COCHRANE Library, and SCOPUS.
Angelica M. Walker, Matthew Cheung, Shaun A. Nguyen, Kate Bonham, Erin A. Harvey, Robert F. Labadie, Ted A. Meyer   +6 more
wiley   +1 more source

Paired associates learning performance in rats requires the nucleus reuniens. [PDF]

Behav Neurosci
Besosa C, Baksh A, Braden R, Tomczak S, Lovett S, Maurer AP, Burke SN.   +6 more
europepmc   +1 more source

Pituri and Nicotin

The Journal of Physiology, 1890
J N, Langley, W L, Dickinson
openaire   +3 more sources

Perioperative Opioid Use and Risk of Persistent Use After Common Otolaryngologic Procedures

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective The objective of this study was to evaluate the incidence of perioperative opioid prescription and the development of new persistent opioid usage in patients prescribed perioperative opioids for common otolaryngological procedures. Study Design Retrospective cohort study. Setting TriNetX US Collaborative Research Network. Methods The
Michael Liu, Austin Lee, Salim Hayek, Shawn Li   +3 more
wiley   +1 more source

Nicotine Suppresses Human Memory Th Cell Subsets With Preferential Effects on Central Memory Th Cells in an α7 Nicotinic Acetylcholine Receptor-Dependent Manner. [PDF]

Eur J Immunol
Gholizadeh F, Hajiaghayi M, Rahbari N, Choi JS, Heidt S, Como A, Kazerouni M, Kargar M, Pinard-LaRoche A, Shih SCC, Darlington PJ.   +10 more
europepmc   +1 more source

Investigation of the Mechanism of Cinnamaldehyde in Irritable Bowel Syndrome Based via Network Pharmacology, Molecular Docking, and Animal Experiments

Pediatric Discovery, EarlyView.
Through network pharmacology and molecular docking, it has been discovered that CA can target MAOB, among other proteins, to exert a therapeutic effect in IBS. In vivo, CA lowered visceral hypersensitivity, anxiety and depression‐like behaviors, and fecal water content, highlighting its therapeutic potential for IBS via anti‐inflammatory pathways ...
Qingyang Yu, Boqing Xu, Chunfang Dai, Yayan Pang, Zhifang Dong   +4 more
wiley   +1 more source

Synthesis and structure of a binuclear calcium nitrate coordination complex with bridging zwitterionic nicotinic acid. [PDF]

Acta Crystallogr E Crystallogr Commun
Burkitbaeva G, Djumanazarova Z, Bektursinova A, Ashurov J, Kadirova S, Choriev O, Meldebekova S, Torambetov B.   +7 more
europepmc   +1 more source

When Fat Goes Astray: Your Liver and Pancreas Get Into Trouble

Portal Hypertension &Cirrhosis, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) and intrapancreatic fat deposition (IPFD) are both common manifestations of ectopic fat accumulation. Although they share multiple risk factors, they also show notable differences in pathological features, standardization of diagnosis, and research maturity.
Yuying Chen, Li Ding, Shan Zhao, Weihong Wang, Jing Zhong, Qiang Yan   +5 more
wiley   +1 more source

Impact of various types of heat treatment on the content of selected B vitamin and their profile in goose breast meat. [PDF]

Poult Sci
Goluch Z, Haraf G, Okruszek A, Stryjecka M, Wereńska M.   +4 more
europepmc   +1 more source