Results 231 to 240 of about 331,963 (334)

5‐Methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT) for alcohol use disorder: An open‐label, phase 2, proof‐of‐concept, clinical trial

Addiction, EarlyView.
Abstract Background and Aims Psychedelic drugs may help treat alcohol use disorder (AUD). This study evaluated BPL‐003, a novel intranasal powder formulation of 5‐methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT) benzoate salt, in people with moderate–severe AUD enrolled in a standard of care, 10‐week programme of relapse‐prevention oriented Cognitive ...
John Marsden, Michael Kelleher, Fiona Dunbar, Anna O. Ermakova, Luke Mitcheson, Claire Roberts, James J. Rucker, Gemma Scott, Ivan Saeger, Francesca Small, Mathieu Seynaeve   +10 more
wiley   +1 more source

Associations between county‐level e‐cigarette‐inclusive Tobacco 21 law population coverage and e‐cigarette use behaviors among United States adolescents in Monitoring the Future

Addiction, EarlyView.
Abstract Background and aims In the United States (US), Tobacco 21 (T21) laws set the minimum legal sale age for all tobacco products to 21 years. This study aimed to examine whether e‐cigarette‐inclusive T21 laws were associated with e‐cigarette use behaviors and related disparities among US adolescents.
James H. Buszkiewicz, Catherine A. Vander Woude, Yanmei Xie, Steven Cook, Bukola Usidame Peters, Megan E. Patrick, Michael R. Elliott, James F. Thrasher, Nancy L. Fleischer   +8 more
wiley   +1 more source

Outdated tools, underestimated harm: Modernizing cannabis surveillance in a post‐legalization era

Addiction, EarlyView.
Abstract Background Canada's 2018 legalization of non‐medical cannabis was positioned as a public health initiative, intended to shift cannabis use from criminalization to regulation. Since then, cannabis access and consumption have grown significantly but the systems used to monitor cannabis‐related harms have not kept pace.
Anees Bahji
wiley   +1 more source

Appetitive responses toward smoking‐related stimuli in abstinence‐motivated, non‐deprived individuals with chronic tobacco dependence: A multi‐methodological investigation

Addiction, EarlyView.
Abstract Background and aims Appetitive responses, such as approach biases, are thought to play a crucial role in smoking. This study aimed to compare responses toward smoking‐related stimuli with responses in control conditions (e.g. non‐approach or neutral stimuli) using a multi‐method approach. By examining associations between response measures and
Franziska Motka, Haoye Tan, Seth M. Levine, Sabine Vollstädt‐Klein, Sarah K. Danböck, Katja Bertsch, Markus H. Winkler, Charlotte E. Wittekind   +7 more
wiley   +1 more source

Trajectories of genetic risk across dimensions of alcohol use behaviors

Addiction, EarlyView.
Abstract Background and aims Alcohol use behaviors (AUBs) manifest in a variety of normative and problematic ways across the life course, all of which are heritable. Twin studies show that genetic influences on AUBs change across development, but this is usually not considered in research identifying and investigating the genes linked to AUBs ...
Jeanne E. Savage, Fazil Aliev, Peter B. Barr, Maia Choi, Gabin Drouard, Megan E. Cooke, Sally I. Kuo, Mallory Stephenson, Sarah J. Brislin, Zoe E. Neale, Spit for Science Working Group, Karen Chartier, Ananda Amstadter, Danielle M. Dick, Emily Lilley, Renolda Gelzinis, Anne Morris, Katie Bountress, Amy E. Adkins, Nathaniel Thomas, Zoe Neale, Kimberly Pedersen, Thomas Bannard, Seung B. Cho, Peter Barr, Holly Byers, Erin C. Berenz, Erin Caraway, James S. Clifford, Megan Cooke, Elizabeth Do, Alexis C. Edwards, Neeru Goyal, Laura M. Hack, Lisa J. Halberstadt, Sage Hawn, Sally Kuo, Emily Lasko, Jennifer Lend, Mackenzie Lind, Elizabeth Long, Alexandra Martelli, Jacquelyn L. Meyers, Kerry Mitchell, Ashlee Moore, Arden Moscati, Aashir Nasim, Jill Opalesky, Cassie Overstreet, A. Christian Pais, Tarah Raldiris, Jessica Salvatore, Jeanne Savage, Rebecca Smith, David Sosnowski, Jinni Su, Chloe Walker, Marcie Walsh, Teresa Willoughby, Madison Woodroof, Jia Yan, Cuie Sun, Brandon Wormley, Brien Riley, Fazil Aliev, Roseann Peterson, Bradley T. Webb, COGA Investigators, Bernice Porjesz, Victor Hesselbrock, Arpana Agrawal, Danielle Dick, Howard J. Edenberg, Tatiana Foroud, Yunlong Liu, Martin H. Plawecki, Samuel Kuperman, Allan Anderson, Jacquelyn Meyers, Laura Bierut, Sarah Hartz, Marc Schuckit, Ronald Hart, Jay Tischfield, Laura Almasy, Alison Goate, Paul Slesinger, Denise Scott, Cathryn Holzhauer, Michie Hesselbrock, Dongbing Lai, John Nurnberger Jr., Leah Wetherill, Xiaoling Xuei, Sean O'Connor, John Kramer, Grace Chan, Chella Kamarajan, Ashwini Pandey, David B. Chorlian, Sivan Kinreich, Gayathri Pandey, Chris Chatzinakos, Jian Zhang, Stacey Saenz deViteri, Christian Richard, Arjun Bingly, Gita Pathak, Andrey Anokhin, Kathleen Bucholz, Fanghong Dong, Alexander Hatoum, Emma Johnson, Vivia McCutcheon, John Rice, Scott Saccone, Zhiping Pang, Sarah Brislin, Jennifer Moore, Alison Merikangas, Miri Gitik, Antti Latvala, Richard J. Rose, Jaakko Kaprio, Danielle M. Dick, Jacquelyn Meyers, Jessica E. Salvatore, Danielle Posthuma   +127 more
wiley   +1 more source

Continuing use of e‐cigarettes after stopping smoking and relapse: Secondary analysis of a large randomised controlled trial

Addiction, EarlyView.
Abstract Background and aims Smokers quitting successfully with the help of e‐cigarettes often continue vaping. It is not known whether this promotes or prevents relapse back to smoking. This study aimed to determine whether use of e‐cigarettes after successful smoking cessation affects the probability of relapse later on.
Peter Hajek, Dunja Przulj, Katie Myers Smith, Jinshuo Li, Peter Sasieni, Louise Ross, Hayden McRobbie, Maciej Goniewicz, Francesca Pesola   +8 more
wiley   +1 more source

Varenicline for cannabis use disorder: A randomized controlled trial

Addiction, EarlyView.
Abstract Background and aims Although cannabis use is widespread and prevalence of cannabis use disorder (CUD) is increasing, limited advancements have been made in CUD medication development. The objective of this study was to test the efficacy of varenicline with medical management for reducing cannabis use in treatment‐seeking individuals with CUD ...
Aimee L. McRae‐Clark, Kevin M. Gray, Nathaniel L. Baker, Brian J. Sherman, Bryan Tolliver, Jessica Burt, Alonzo Steplight, Elizabeth Chapman, Amanda Wagner   +8 more
wiley   +1 more source

A meta‐analysis of sexual orientation inequities in substance use among youth

Addiction, EarlyView.
Abstract Background and Aims Sexual minority youth report significantly higher rates of substance use than heterosexual youth, yet a comprehensive and systematic evaluation and synthesis of the magnitude of this inequity has not been conducted. The purpose of this study was to conduct a meta‐analysis to assess the magnitude of overall inequities in ...
Ethan H. Mereish, Hyemin Lee, Jeremy T. Goldbach, Sophie Hathaway, Emily A. Hennessy   +4 more
wiley   +1 more source

Addiction‐related problems in Japan: A regional perspective

Addiction, EarlyView.
Abstract Japan's addiction landscape appears paradoxical. The lifetime use of illicit drugs is among the lowest in Organisation for Economic Cooperation and Development countries, but harm from alcohol, tobacco, and gambling ranks among the world's highest.
Soichiro Ide, Yoko Nishitani, Masahiko Sumitani, Masabumi Minami, Tadashi Isa, Masako Iseki, Michiko Ohkura, Hitoshi Okamoto, Tetsuro Kikuchi, Yuko Sekino, Hidehiko Takahashi, Kenji Takeuchi, Atsumi Nitta, Takeshi Honjo, Hiroshi Matsumoto, Tsuyoshi Miyakawa, Toshiya Murai, Toshihiko Matsumoto, Kazuyuki Nakagome, Kazutaka Ikeda   +19 more
wiley   +1 more source