Results 231 to 240 of about 329,742 (333)

The Brain Metabolite Kynurenic Acid Inhibits α7 Nicotinic Receptor Activity and Increases Non-α7 Nicotinic Receptor Expression: Physiopathological Implications

open access: yesJournal of Neuroscience, 2001
C. Hilmas   +5 more
semanticscholar   +1 more source

Neural mechanisms and clinical features of anti‐influenza drug‐related psychiatric adverse events

open access: yesVIEW, EarlyView.
Anti–influenza drugs, while essential, have been increasingly associated with psychiatric adverse events (pAEs). Our study systematically investigated these pAEs by utilizing large pharmacovigilance databases and animal models, thereby revealing key clinical features and underlying neural mechanisms.
Anqi Lin   +9 more
wiley   +1 more source

Silibinin‐driven microbial and metabolic reprogramming restores CD4+ T cell immunity in HIV immunological nonresponders

open access: yesVIEW, EarlyView.
Despite efficacious antiretroviral therapy, 10%–40% of HIV‐infected individuals exhibit inadequate immune reconstitution due to persistent inflammatory activation and NAD+ metabolic dysregulation—a critical cofactor in cellular bioenergetics. We administered silibinin to 53 HIV immunological non‐responders and elucidated its mechanism through selective
Wenli Liu   +13 more
wiley   +1 more source

The ATP-mediated cytokine release by macrophages is down-modulated by unconventional α9* nicotinic acetylcholine receptors. [PDF]

open access: yesFront Immunol
Wolf PMK   +16 more
europepmc   +1 more source

Management of Vocal Fold Leukoplakia

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Vocal fold leukoplakia (VFL) is a descriptive term for a white plaque in the true vocal folds (TVF). It is estimated at 10.2 cases per 100,000 males and 2.1 per 100,000 females. The most critical aspect of managing a VLF is achieving an accurate pathological diagnosis, since a white plaque in the TVF can have numerous differential diagnoses ...
Isabela H. Schettini, Thomas L. Carroll
wiley   +1 more source

Cholinergic system in schizophrenia: A systematic review and meta-analysis. [PDF]

open access: yesMol Psychiatry
Saint-Georges Z   +7 more
europepmc   +1 more source

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