Results 191 to 200 of about 145,182 (364)

Differential Effects of Quercetin and Quercetin Glycosides on Human α7 Nicotinic Acetylcholine Receptor-Mediated Ion Currents

, 2016
Byunghwan Lee, Sun-Hye Choi, Hyeon‐Joong Kim, Seokwon Jung, Sung‐Hee Hwang, Mi-Kyung Pyo, Hyewhon Rhim, Hyoung‐Chun Kim, Ho-Kyoung Kim, Sang‐Mok Lee, Seung‐Yeol Nah   +10 more
openalex   +2 more sources

Amyloid Beta in Alzheimer's Disease: Mechanisms, Biomarker Potential, and Therapeutic Targets

CNS Neuroscience &Therapeutics, Volume 31, Issue 12, December 2025.
The limited clinical efficacy of anti‐Aβ antibodies has challenged the Aβ hypothesis, compelling the integration of key mechanisms—including neuroinflammation, mitochondrial dysfunction, oxidative stress, and post‐translational modifications of Aβ—into a revised model of Alzheimer's disease.
Shamseddin Ahmadi, Shiler Khaledi, Kimia Ahmadi, Kambiz Hassanzadeh   +3 more
wiley   +1 more source

Novel 5-(quinuclidin-3-ylmethyl)-1,2,4-oxadiazoles to investigate the activation of the α7 nicotinic acetylcholine receptor subtype: Synthesis and electrophysiological evaluation

, 2018
Marta Quadri, Almin Silnović, Carlo Matera, Nicole A. Horenstein, Clare Stokes, Marco De Amici, Roger L. Papke, Clelia Dallanoce   +7 more
openalex   +2 more sources

Engineering exosomes for Alzheimer's disease: Multi‐target therapeutic strategies from pathogenesis to clinical translation

Clinical and Translational Medicine, Volume 15, Issue 12, December 2025.
Exosomes, modified through multidimensional approaches including physical, chemical and genetic means, and equipped with brain‐targeted peptides and therapeutic agents, are capable of crossing the blood‒brain barrier for precise delivery. They can simultaneously remove amyloid‐beta plaques and neurofibrillary tangle, inhibit neuroinflammation, and pave
Yuehan Zhang, Zhenyang Li, Haien Guan, Zhenhua Qiu, Chunlin Zou   +4 more
wiley   +1 more source

Cognitive correlates of α4β2 nicotinic acetylcholine receptors in mild Alzheimer’s dementia [PDF]

, 2018
Osama Sabri, Philipp Meyer, Susanne Gräf, Swen Hesse, Stephan Wilke, Georg‐Alexander Becker, Michael Rullmann, Marianne Patt, Julia Luthardt, Gudrun Wagenknecht, Alexander Hoepping, René Smits, Annegret Franke, Bernhard Sattler, Solveig Tiepolt, Steffen Fischer, Winnie Deuther‐Conrad, Ulrich Hegerl, Henryk Barthel, Peter Schönknecht, Peter Brust   +20 more
openalex   +1 more source

Cannabidiol as a Neuroprotective Agent in Acrylamide‐Induced Neurotoxicity: Effects on Oxidative Stress, Inflammation, and Cholinergic Function in Male Mice

Journal of Neuroscience Research, Volume 103, Issue 12, December 2025.
Cannabidiol (CBD) protects against acrylamide‐induced neurotoxicity in mice by reducing oxidative stress, inflammation, and cholinergic dysfunction, while restoring BDNF levels. These findings highlight CBD's potential as a therapeutic agent for preventing environmental neurotoxicity and supporting brain health.
Korina Atsopardi, Konstantinos Mesiakaris, Ioannis Sotiropoulos, Marigoula Margarity, Konstantinos Poulas   +4 more
wiley   +1 more source

The α7 Nicotinic Acetylcholine Receptor Agonist GTS-21 Improves Bacterial Clearance in Mice by Restoring Hyperoxia-Compromised Macrophage Function [PDF]

, 2014
Ravikumar Sitapara, Daniel J. Antoine, Lokesh Sharma, Vivek Patel, Charles R. Ashby, Samir Gorasiya, Huan Yang, Michelle Zur, Lin L. Mantell   +8 more
openalex   +1 more source

The Transgenerational Link: Breeder Gut Microbiota and Broiler Progeny Development

MicrobiologyOpen, Volume 14, Issue 6, December 2025.
The breeder hen gut microbiome, shaped by maternal factors and targeted nutrition, drives reproductive performance and transmits beneficial microbes that programme gut health, immunity, and growth in progeny. Microbiome‐focused interventions can optimise egg quality, hatchability, progeny performance, and sustainability in poultry production.
Gladys Maria Pangga, Stephen Bamford, Anne Richmond, Nicolae Corcionivoschi, Umer Zeeshan Ijaz, Ozan Gundogdu   +5 more
wiley   +1 more source

Stimulation of the α7 Nicotinic Acetylcholine Receptor Protects against Neuroinflammation after Tibia Fracture and Endotoxemia in Mice [PDF]

, 2014
Niccolò Terrando, Ting Yang, Jae Kyu Ryu, Phillip T. Newton, Claudia Monaco, Marc Feldmann, Daqing Ma, Katerina Akassoglou, Mervyn Maze   +8 more
openalex   +1 more source

The phenolic monoterpenoid carvacrol inhibits the binding of nicotine to the housefly nicotinic acetylcholine receptor.

Pest Management Science, 2013
F. Tong, A. Gross, M. Dolan, J. Coats
semanticscholar   +1 more source