Results 191 to 200 of about 78,616 (322)

Management of Anxiety in Parkinson's Disease

Movement Disorders Clinical Practice, Volume 12, Issue 10, Page 1490-1501, October 2025.
ABSTRACT Background Anxiety is a common, distressing, hard‐to‐diagnose and hard‐to‐treat symptom in Parkinson's disease. No formal guidelines exist to assist management. Objective We provide a pragmatic guide to detecting and managing anxiety in Parkinson's disease.
Alex J. Berry, Harry Costello, Silvia Jesús, Gary Price, Ashwani Jha   +4 more
wiley   +1 more source

Induction of Na⁺/K⁺‐ATPase activity by long‐term stimulation of nicotinic acetylcholine receptors in C2C12 myotubes [PDF]

, 1994
Robert H. Henning, S.Adriaan Nelemans, Jan van den Akker, A. den Hertog   +3 more
openalex   +1 more source

Antifibrotic Effects of an α7 Nicotinic Acetylcholine Receptor Agonist in Keloid Fibroblasts and a Rat Scar Model. [PDF]

Int J Mol Sci
Roh H, Kim YH, Heo KJ, Hong JW, Lee WJ.
europepmc   +1 more source

Proteolytic stabilization of a spider venom peptide results in an orally active bioinsecticide

Pest Management Science, Volume 81, Issue 10, Page 6404-6415, October 2025.
Selective editing out of an insect gut protease cleavage site renders a spider‐derived insecticidal peptide active by ingestion by insect pests. Abstract BACKGROUND The toxin peptide U1‐AGTX‐Ta1b from the Hobo spider, Eratigena agrestis (Walckenaer, 1802), was studied to determine its potential to serve as a bioinsecticide.
Breck R. Davis, Alexandra M. Haase, Joseph S. Tourtois, Daniel L. Hulbert, Rachel E. Cornell, Brian T. DeVree, Cadence J. Flohrschutz, Lucille M. Bell, Daniel C. Peck, Trang T. Nguyen, Lin Bao, Robert M. Kennedy, Kyle D. Schneider   +12 more
wiley   +1 more source

Structural insights into the progressive recovery of α7 nicotinic acetylcholine receptor from nicotine-induced desensitization. [PDF]

Sci Adv
Liu S, Chen H, Zhu X, Ye F, Zhao Y, Qin J, Zheng Y, Wang X, Zhang L, Chen H, Li X, Mu W, Fu Y, Luo C, Hou H, Bai C, Liu L, Tian C.   +17 more
europepmc   +1 more source

KYNA Ameliorates Hepatic Ischemia–Reperfusion Injury by Activating the Hippo Signalling Pathway via FTO‐Dependent m6A Demethylation of LATS1

Cell Proliferation, Volume 58, Issue 10, October 2025.
Our study elucidates the cellular and molecular mechanisms underlying KYNA's protective effects against HIRI. It emphasises that KYNA modulates the methylation status of the Hippo signalling pathway through the activation of AHR, thereby mitigating damage by promoting LATS1 degradation and facilitating the nuclear translocation of YAP. ABSTRACT Hepatic
Wenjie Zheng, Xiaowen Wang, Haoqi Chen, Kaiming He, Xijing Yan, Yuan Zhang, Yang Yang, Peng Zhang, Wenfeng Zhu, Shuguang Zhu, Hua Li   +10 more
wiley   +1 more source

Nicotine in e-cigarette aerosol reduces GABA neuron migration via the α7 nicotinic acetylcholine receptor. [PDF]

Sci Rep
Parnell AA, McCarthy DM, Trupiano MX, Schatschneider C, Bhide PG.   +4 more
europepmc   +1 more source

Astrocytes as Active Participants in Memory

Journal of Neurochemistry, Volume 169, Issue 10, October 2025.
This review explores how astrocytes support memory by modulating neurotransmitters, interacting with biomolecules, and taking part in synaptic plasticity. We discuss their role across various brain regions and spotlight cutting‐edge methods—such as Ca2+ imaging, optogenetics, chemogenetics, and engram analysis—that have revolutionized our ability to ...
Shay Meron Asher, Inbal Goshen
wiley   +1 more source

Triphenylmethylphosphonium is an ion channel ligand of the nicotinic acetylcholine receptor.

, 1982
L Lauffer, Ferdinand Hucho
openalex   +1 more source

Targeting Neuronal Alpha7 Nicotinic Acetylcholine Receptor Upregulation in Age-Related Neurological Disorders. [PDF]

Cell Mol Neurobiol
Abraham SM, Suresh S, Komal P.
europepmc   +1 more source