Results 211 to 220 of about 79,918 (320)

Nicotine Regulates LPS‐Induced Inflammatory Responses in HMC3 Microglia and Exerts Neuronal Protection

open access: yesMediators of Inflammation, Volume 2026, Issue 1, 2026.
Microglia‐mediated neuroimmune responses have been implicated in central nervous system injury and disease pathogenesis. The α7 nicotinic acetylcholine receptor (α7 nAChR), which is expressed on microglia and participates in microenvironment interactions, is a key mediator of the cholinergic anti‐inflammatory pathway.
Yuhan Qin   +9 more
wiley   +1 more source

α7 nicotinic acetylcholine receptor agonist attenuates lipopolysaccharide-induced acute kidney injury in mice by reducing CCL2 expression in macrophages. [PDF]

open access: yesSci Rep
Matsuo S   +9 more
europepmc   +1 more source

Characterization of a Bovine Serum Albumin‐Derived Pro‐Cognitive Peptide (bSAPP): An Orally Active Peptide Alleviates Cognitive Decline in HFD‐Fed Mice via CCK Signaling Through the Gut‐Brain Axis

open access: yesThe FASEB Journal, Volume 39, Issue 24, 31 December 2025.
The popularity of the Western diet has increased the prevalence of dementia in addition to aging. We found that the digest of bovine serum albumin and a peptide derived from the digest showed an oral pro‐cognitive effect in mice fed a high‐fat diet (HFD). We named the peptide bSAPP (EC50 = 0.01 mg/kg BW). The oral effect of bSAPP was modulated by CCK1R
Biyun Zhang   +5 more
wiley   +1 more source

Impact of white matter hyperintensities on α4β2 nicotinic acetylcholine receptor binding in the human brain. [PDF]

open access: yesEur J Nucl Med Mol Imaging
Rullmann M   +5 more
europepmc   +1 more source

Stimulation of the α7 Nicotinic Acetylcholine Receptor Protects against Neuroinflammation after Tibia Fracture and Endotoxemia in Mice [PDF]

open access: gold, 2014
Niccolò Terrando   +8 more
openalex   +1 more source

Molecular insights into the α6β4 nicotinic acetylcholine receptor function and ligand recognition. [PDF]

open access: yesNat Commun
Su J   +10 more
europepmc   +1 more source

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