Results 131 to 140 of about 29,145 (307)

Impact of severe periodontitis and diabetes mellitus on recurrent cardiovascular outcomes

Journal of Periodontology, EarlyView.
Abstract Background This post hoc analysis of the Periodontitis and Coronary Heart Disease study (ClinicalTrials.gov Identifier: NCT01045070) aimed to determine the association between diabetes and recurrent cardiovascular events (CVEs) in patients with cardiovascular disease (CVD) and severe periodontitis.
Stefan Reichert, Axel Schlitt, Selina Rehm, Susanne Schulz   +3 more
wiley   +1 more source

Mapping the subgingival HerBiome and HisBiome over the human healthspan

Journal of Periodontology, EarlyView.
Abstract Background Understanding the intricate relationship between sex, age, and the oral microbiome is crucial for deciphering the onset and progression of numerous age‐related oral and systemic diseases. Methods Subgingival plaque was collected from 781 periodontally and systemically healthy females and 160 males spanning 0 to 80 years.
Rahul Nikam, Kazune Pax, Michelle Lee‐Scott Beverly, Purnima S. Kumar   +3 more
wiley   +1 more source

Investigation of the Mechanism of Cinnamaldehyde in Irritable Bowel Syndrome Based via Network Pharmacology, Molecular Docking, and Animal Experiments

Pediatric Discovery, EarlyView.
Through network pharmacology and molecular docking, it has been discovered that CA can target MAOB, among other proteins, to exert a therapeutic effect in IBS. In vivo, CA lowered visceral hypersensitivity, anxiety and depression‐like behaviors, and fecal water content, highlighting its therapeutic potential for IBS via anti‐inflammatory pathways ...
Qingyang Yu, Boqing Xu, Chunfang Dai, Yayan Pang, Zhifang Dong   +4 more
wiley   +1 more source

A tight coupling between β\u3csub\u3e2\u3c/sub\u3eY97 and β\u3csub\u3e2\u3c/sub\u3eF200 of the GABA\u3csub\u3eA\u3c/sub\u3e receptor mediates GABA binding [PDF]

, 2011
The GABAA receptor is an oligopentameric chloride channel that is activated via conformation changes induced upon the binding of the endogenous ligand, GABA, to the extracellular inter-subunit interfaces. Although dozens of amino acid residues at the α/β
Laha, Kurt T., Tran, Phu N., Wagner, David A.   +2 more
core   +1 more source

Effects of bioinsecticide exposure route on aphids and their natural enemies in oilseed rape

Pest Management Science, EarlyView.
Fatty acids, silicone polymers and surfactants reduced aphid numbers but caused natural enemy mortality under direct exposure, while minimal residual activity suggests potential for targeted, compatible use in integrated pest management. Abstract BACKGROUND Myzus persicae Sulzer and Brevicoryne brassicae L.
Aimee J. Tonks, Tom W. Pope, Simon Cooper, Joe M. Roberts   +3 more
wiley   +1 more source

Seedling resistance and chemical defenses against Psylliodes chrysocephala: the roles of seed age and sinapinic acid in Sinapis alba and Brassica napus

Pest Management Science, EarlyView.
The cabbage stem flea beetle (Psylliodes chrysocephala) is a major pest of winter oilseed rape (Brassica napus). We tested B. napus and Sinapis alba seedlings for feeding resistance and underlying chemical defenses. S. alba was least damaged, while metabolite profiles revealed resistance‐linked compounds, highlighting breeding potential for insect ...
Daniel Rüde, Samantha M Cook, Bernd Ulber, Tobias Pöhnl, Michael Rostás   +4 more
wiley   +1 more source

Exploring the Impact of Polystyrene Microplastic Beads on Male Gonads of the Marine Mussel, Mytilus galloprovincialis

Environmental Toxicology, EarlyView.
ABSTRACT Plastic, with its remarkable versatility and numerous applications, has greatly benefited humanity. However, its extreme resistance to natural degradation means it persists in the environment for long periods, causing global environmental problems.
Teresa Chianese, Mariachiara Galati, Tiziana Cappello, Maria Maisano, Gennaro Lettieri, Carmela Marinaro, Marina Piscopo, Gianluca Fasciolo, Carlos Gravato, Gaetana Napolitano, Giulia Paolella, Annamaria Locascio, Rosaria Scudiero, Luigi Rosati   +13 more
wiley   +1 more source

Toxicity of Four Common Environmental Chemicals Across Caenorhabditis elegans Life Stages Supporting the One Health Concept

Environmental Toxicology, EarlyView.
ABSTRACT Pesticides and pharmaceuticals are among the most common chemical groups in waterbodies and soils, and their universal distribution raises concerns about potential adverse effects on nontarget organisms and humans. Reproductive output disruption is of particular concern, as it transposes effects from the individual to the next generations at ...
Fábio Campos, Maria D. Pavlaki, Amadeu M. V. M. Soares, Susana Loureiro   +3 more
wiley   +1 more source

Synergistic and Antagonistic Effects of Chemical Pollutants and Parasitic Fungi on Cyanobacterial Metabolism

Environmental Toxicology, EarlyView.
ABSTRACT Freshwater ecosystems are increasingly impacted by anthropogenic pollutants, including the widely used herbicide metolachlor (MET) and cigarette butt (CB) litter. Parasites represent an additional biotic stressor that can modulate pollutant effects on their hosts.
Erika Berenice Martínez‐Ruiz, Jutta Fastner, Stephanie Spahr, Justyna Wolinska   +3 more
wiley   +1 more source

Chrysin Mitigates Acetamiprid‐Induced Testicular Injury in Mice via Suppression of Endoplasmic Reticulum Stress and Inflammation

Environmental Toxicology, EarlyView.
ABSTRACT Acetamiprid (ACP) is a neonicotinoid pesticide that is extensively utilized for the management of insect populations, but its toxic effects on the male reproductive system have become a source of concern. Chrysin (CHR) is a natural flavone found in many plants and bee products, including honey and propolis.
Selim Demir, Nihal Turkmen Alemdar, Esin Yulug, Ali Kulaber, Elif Ayazoglu Demir, Nadire Sevdenur Erdogan, Ahmet Mentese, Yuksel Aliyazicioglu   +7 more
wiley   +1 more source