Results 251 to 260 of about 29,145 (307)

Activating Muscarinic Receptor Signaling in Intrapancreatic Neurons Is Required for Parasympathetic Cholinergic Control of Pancreatic Cell Function. [PDF]

Diabetes
Levi NJ, Tamayo Garcia A, Sokolov M, Barro-Soria R, Caicedo A.   +4 more
europepmc   +1 more source

Regulation of Melanogenesis in Skin Epidermal Keratinocytes via Activation of α7 Nicotinic Acetylcholine Receptor on the Expression of α-Melanocyte-Stimulating Hormone. [PDF]

FASEB J
Guo MS, Wang X, Xia Y, Wu J, Dilidaer A, Gao J, Dong TT, Tsim KWK.   +7 more
europepmc   +1 more source

Light-Activated Pharmacological Tools for Exploring the Cholinergic System. [PDF]

Med Res Rev
Colleoni A, Galli G, Dallanoce C, De Amici M, Gorostiza P, Matera C.   +5 more
europepmc   +1 more source

Unlocking the Neurogenic Potential of Enteric Glial Cells for Hirschsprung Disease Therapy. [PDF]

Cell Mol Gastroenterol Hepatol
Van Mechelen K, Zhao J, Di Natale MR, Jiang L, Lai DK, Yu H, Oviedo Querejazu M, Furness JB, Vanden Berghe P, Hao MM, Stamp LA.   +10 more
europepmc   +1 more source

NICOTINIC ANTAGONIST EFFECTS ON FUNCTIONAL ATTENTION NETWORKS

, 2018
Thienel, Renate, Voss, B., Kellermann, Thilo, Reske, Martina, Halfter, Sarah, Sheldrick, A. J., Radenbach, Katrin E., Habel, Ute, Schneider, F., Shah, N. Jon, Schall, Ulrich, Kircher, Tilo T. J.   +11 more
openaire   +1 more source

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Nonclassical nicotine antagonists

Journal of Medicinal Chemistry, 1975
A series of "nonclassical" nicotine antagonists was synthesized and compared to the "classical" nicotine antagonist, hexamethonium, by means of the isolated guinea pig atria preparation. 2 was found to be the most potent, followed by hexamethonium and the other antagonists.
Charles F. Barfknecht, Clinton A. Taylor, Lawrence A. Peterson, Fouad M. Sharabi, John P. Long   +4 more
openaire   +2 more sources

Bupropion Is a Nicotinic Antagonist

The Journal of Pharmacology and Experimental Therapeutics, 2000
Neuronal nicotinic receptors are ligand-gated ion channels of the central and peripheral central nervous system that regulate synaptic activity from both pre- and postsynaptic sites. The present study establishes the acute interaction of bupropion, an antidepressant agent that is also effective in nicotine dependence, with nicotine and nicotinic ...
J E, Slemmer, B R, Martin, M I, Damaj
openaire   +2 more sources

Influencing cigarette smoking with nicotine antagonists

Psychopharmacologia, 1973
Antagonists of nicotine have been used in an attempt to resolve the continuing controversy about the role of nicotine as the primary reinforcer in cigarette smoking. Mecamylamine, an antagonist which readily penetrates to the central nervous system, increased the rate of cigarette smoking by about 30% in laboratory tests; this was accompanied by ...
I P, Stolerman, T, Goldfarb, R, Fink, M E, Jarvik   +3 more
openaire   +2 more sources

Methyl lycaconitine: A novel nicotinic antagonist

Molecular and Cellular Neuroscience, 1992
Methyllycaconitine (MLA), a natural toxin from Delphinium seeds, was investigated for its ability to antagonize nicotinic responses in several preparations representing different subtypes of neuronal nicotinic acetylcholine receptor. A presynaptic nicotinic receptor mediating dopamine release from rat striatal synaptosomes was blocked by 10 muM MLA, in
A, Drasdo, M, Caulfield, D, Bertrand, S, Bertrand, S, Wonnacott   +4 more
openaire   +2 more sources

Blockade of Nicotine Self-Administration with Nicotinic Antagonists in Rats

Pharmacology Biochemistry and Behavior, 1999
The reinforcing properties of a variety of drugs abused by humans have been investigated using the technique of intravenous self-administration in the rat. To examine the effect of nicotine dose on nicotine self-administration, Wistar rats were allowed to self-administer various doses of nicotine using a within-subjects Latin square design. An inverted
S S, Watkins, M P, Epping-Jordan, G F, Koob, A, Markou   +3 more
openaire   +2 more sources