Results 211 to 220 of about 57,977 (335)

Activation of Neuronal Nicotinic Receptors Inhibits Acetylcholine Release in the Neuromuscular Junction by Increasing Ca²⁺ Flux through Ca_v1 Channels. [PDF]

Int J Mol Sci, 2021
Zhilyakov N, Arkhipov A, Malomouzh A, Samigullin D.   +3 more
europepmc   +1 more source

Formation of the alpha-bungarotoxin binding site and assembly of the nicotinic acetylcholine receptor subunits occur in the endoplasmic reticulum.

, 1987
McHardy M. Smith, Jon Lindstrom, John P. Merlie   +2 more
openalex   +1 more source

d-Tubocurarine binding sites are located at alpha-gamma and alpha-delta subunit interfaces of the nicotinic acetylcholine receptor. [PDF]

, 1990
Steen E. Pedersen, Jonathan B. Cohen
openalex   +1 more source

Serum Proteomic and Metabolomic Signatures of High Versus Low Physical Function in Octogenarians

Aging Cell, EarlyView.
Circulating factors are strongly implicated in modulating biological aging. In this study we show that the serum proteomic and metabolomic profile of high functioning octogenarians suggests lower activation of SASP, preservation of the tryptophan‐kynurenic pathway, higher lipophosphatidyl cholines promoting mitochondrial function, and reduced ...
Ceereena Ubaida‐Mohien, Ruin Moaddel, Sally Spendiff, Norah J. MacMillan, Marie‐Eve Filion, Jose A. Morais, Julián Candia, Liam F. Fitzgerald, Tanja Taivassalo, Paul M. Coen, Luigi Ferrucci, Russell T. Hepple   +11 more
wiley   +1 more source

The potential effect of α7 nicotinic receptors modulation on palatable food-induced dependence-like behaviors. [PDF]

Saudi Pharm J
Alameen AA, AlSharari SD, Alshammari MA, Damaj MI, Sari Y.   +4 more
europepmc   +1 more source

Partial Agonist Activity of Neonicotinoids on Rat Nicotinic Receptors: Consequences over Epinephrine Secretion and In Vivo Blood Pressure. [PDF]

Int J Mol Sci, 2021
Park J, Taly A, Bourreau J, De Nardi F, Legendre C, Henrion D, Guérineau NC, Legros C, Mattei C, Tricoire-Leignel H.   +9 more
europepmc   +1 more source

Nicotinamide Riboside Supplementation Alleviates Testicular Aging Induced by Disruption of Qprt‐Dependent NAD+ De Novo Synthesis in Mice

Aging Cell, EarlyView.
In Qprt‐deficient mice, testicular NAD+ levels decline accelerated with age, leading to mitochondrial dysfunction, disrupted DSB repair, impaired meiotic sex chromosome inactivation, and germ cell loss. Nicotinamide riboside (NR) supplementation restores NAD+ levels and alleviates these defects, highlighting the importance of NAD+ de novo synthesis in ...
Yining Xu, Huan Wang, Hui Li, Chenlu Wei, Zhenye Zhu, Yanqing Zhao, Jiajia Zhu, Min Lei, Yingpu Sun, Qingling Yang   +9 more
wiley   +1 more source

The role of nicotinic receptors in SARS-CoV-2 receptor ACE2 expression in intestinal epithelia [PDF]

Bioelectron Med, 2020
Hove ASt, Brinkman DJ, Yim AYL, Verseijden C, Hakvoort TB, Admiraal I, Welting O, Hamersveld PHv, Sinniger V, Bonaz B, Luyer MD, de Jonge WJ.   +11 more
europepmc   +2 more sources

Nicotinic Receptors in Human Chromaffin Cells: Characterization, Functional and Physical Interactions between Subtypes and Regulation. [PDF]

Int J Mol Sci
Jiménez-Pompa A, Albillos A.
europepmc   +1 more source

Contingency management to promote treatment engagement in comorbid alcohol use disorder and alcohol‐related liver disease: Findings from a pilot randomized controlled trial

Alcohol, Clinical and Experimental Research, EarlyView.
This pilot trial explored the feasibility of contingency management to promote treatment engagement in patients with comorbid alcohol use disorder and alcohol‐related liver disease. Participants were offered integrated care, and those in the intervention arm were additionally offered a voucher‐based contingency management intervention.
Sofia Hemrage, Nicola Kalk, Naina Shah, Stephen Parkin, Paolo Deluca, Colin Drummond   +5 more
wiley   +1 more source